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Production of exotic neutron-deficient isotopes near N, Z=50 in multinucleon transfer reactions
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作者 许馨心 张根 +10 位作者 李静静 李冰 CheikhA.T.Sokhna 张欣蕊 杨秀秀 程诗慧 张钰海 葛志帅 李成 刘忠 张丰收 《中国物理C:英文版》 SCIE CAS CSCD 2019年第6期51-58,共8页
The multinucleon transfer reaction in the collisions of 40 Ca+^124 Sn at Ec.m.= 128.5 MeV is investigated using the improved quantum molecular dynamics model. The measured angular distributions and isotopic distributi... The multinucleon transfer reaction in the collisions of 40 Ca+^124 Sn at Ec.m.= 128.5 MeV is investigated using the improved quantum molecular dynamics model. The measured angular distributions and isotopic distributions of the products are reproduced reasonably well by the calculations. The multinucleon transfer reactions of 40 Ca+^112 Sn, 58 Ni+^112 Sn, 106 Cd+^112 Sn, and 48 Ca+^112 Sn are also studied. This demonstrates that the combinations of neutron-deficient projectile and target are advantageous for the production of exotic neutron-deficient nuclei near N,Z =50. The charged particles’ emission plays an important role at small impact parameters in the de-excitation processes of the system. The production cross sections of the exotic neutron-deficient nuclei in multinucleon transfer reactions are much larger than those measured in the fragmentation and fusion-evaporation reactions. Several new neutron-deficient nuclei can be produced in the 106 Cd+^112 Sn reaction. The corresponding production cross sections for the new neutron-deficient nuclei,101,112 Sb,103 Te,and 106,107) I,are 2.0 nb,4.1 nb,6.5 nb,0.4 μb and 1.0 μb,respectively. 展开更多
关键词 PRODUCTION CROSS-SECTIONS EXOTIC neutron-deficient NUCLEI PRODUCTION cross SECTIONS
电化学方法把铂丝转化到碳布上形成铂二十面体和纳米立方体并用于电催化产氢
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作者 罗志敏 谭超良 +11 位作者 赖壮钗 张晓 陈君泽 陈也 陈博 拱越 张志成 吴雪军 李冰 宗昀 谷林 张华 《中国科学:材料科学(英文版)》 CSCD 2019年第1期115-121,共7页
湿化学法可控合成贵金属纳米结构通常需要金属盐或金属配合物作为前体,并利用表面活性剂和配体来调节和稳定纳米结构的形貌.本文通过一种简单的电化学方法(线性扫描伏安法),在三电极体系中直接把铂线转化到碳布表面形成铂二十面体和纳... 湿化学法可控合成贵金属纳米结构通常需要金属盐或金属配合物作为前体,并利用表面活性剂和配体来调节和稳定纳米结构的形貌.本文通过一种简单的电化学方法(线性扫描伏安法),在三电极体系中直接把铂线转化到碳布表面形成铂二十面体和纳米立方体.在三电极体系中,铂线、碳布和Ag/AgCl(3mol L^-1KCl)分别作为对电极、工作电极和参比电极.与商业Pt/c催化剂相比,制备的铂二十面体和纳米立方体展现出优越的电催化活性.该方法简单、有效,可拓展到其他贵金属纳米结构的合成和应用研究.如通过这种电化学方法直接将Au、Pd等块体材料转化成具有各种潜在应用的Au、Pd等纳米结构. 展开更多
关键词 电化学方法 纳米结构 电催化活性 二十面体 立方体 铂丝 碳布 转化
高校计算机三维动画课程设计与教学改革研究
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作者 李冰 张淋江 《计算机产品与流通》 2018年第4期178-179,共2页
三维动画是近年来社会上人才紧缺的领域之一,而目前高校培养的三维动画人才和社会需求存在一定的差距。传统高校三维动画课程中存在多种问题,比如学生被动完成案例,无法对知识进行迁移,缺乏对三维动画整体的宏观认识等。根据存在的诸多... 三维动画是近年来社会上人才紧缺的领域之一,而目前高校培养的三维动画人才和社会需求存在一定的差距。传统高校三维动画课程中存在多种问题,比如学生被动完成案例,无法对知识进行迁移,缺乏对三维动画整体的宏观认识等。根据存在的诸多问题,本人从自身三维动画教学经验出发,提出多种教学改革措施,以促进三维动画教学效果的提升,培养符合社会需求的三维动画人才。 展开更多
关键词 三维动画教学 教学改革 项目教学 课程设计
长链非编码RNA HOTAIR对胃肠间质瘤细胞化疗敏感性的影响 预览 被引量:1
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作者 李冰 熊正方 郭亚民 《中国现代医学杂志》 2018年第27期15-21,共7页
目的研究长链非编码RNA(lncRNA)HOTAIR对胃肠间质瘤细胞伊马替尼化疗敏感性的影响,并探讨其作用机制。方法首先在胃肠间质瘤组织中检测HOTAIR的表达水平。选择胃肠间质瘤细胞GIST-T1为研究对象,si干扰HOTAIR后,采用dUTP缺口末端标记测定... 目的研究长链非编码RNA(lncRNA)HOTAIR对胃肠间质瘤细胞伊马替尼化疗敏感性的影响,并探讨其作用机制。方法首先在胃肠间质瘤组织中检测HOTAIR的表达水平。选择胃肠间质瘤细胞GIST-T1为研究对象,si干扰HOTAIR后,采用dUTP缺口末端标记测定法(TUNEL)和半抑制浓度(IC50)法检测GIST-T1对伊马替尼化疗敏感性的变化。通过实时荧光定量聚合酶链反应(qRT-PCR)法、RNAhybird软件分析和荧光素酶报告法,筛选并验证与HOTAIR存在内源性竞争关系的miRNAs。最后将miRNA与HOTAIR共转染,观察HOTAIR与miRNA的竞争性结合能否改变GIST-T1细胞对伊马替尼的化疗敏感性。结果HOTAIR在胃肠间质瘤组织中表达含量高于正常组织(P<0.05)。伊马替尼药物作用下,si-HOTAIR组细胞IC50低于si-NC组(P<0.05);TUNEL阳性细胞比例高于si-NC组(P<0.05);差异有统计学意义。qRT-PCR结果显示,si-HOTAIR组细胞miRNA-21表达水平高于si-NC组(P<0.05);RNAhybird分析及荧光素酶验证结果显示HOTAIR与miR-21核心序列区存在碱基互补。将miRNA-21与HOTAIR共转染GIST-T1细胞后,与miRNA-21+HOTAIR-突变型组比较,miRNA-21+HOTAIR-野生型组细胞IC50增高(P<0.05);TUNEL阳性细胞比例降低,差异有统计学意义(P<0.05)。结论长链非编码RNAHOTAIR可通过内源性竞争结合miRNA-21,降低胃肠间质瘤细胞对伊马替尼的化疗敏感性。 展开更多
关键词 长链非编码RNA 胃肠间质瘤 化疗 MIRNAS
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Computed tomography-guided catheter drainage with urokinase and ozone in management of empyema 预览
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作者 Bing Li Chuan Liu +5 位作者 Yang Li Han-Feng Yang Yong Du Chuan Zhang Hou-Jun Zheng Xiao-Xue Xu 《世界放射学杂志:英文版(电子版)》 2017年第4期212-216,共5页
AIM To retrospectively compare the outcomes of catheter drainage,urokinase and ozone in management of empyema.METHODS Retrospective study included 209 patients(111 males and 98 females; age range 19 to 72 years) who w... AIM To retrospectively compare the outcomes of catheter drainage,urokinase and ozone in management of empyema.METHODS Retrospective study included 209 patients(111 males and 98 females; age range 19 to 72 years) who were diagnosed with empyema.The patients were divided into 3 groups based on the therapy instituted: catheter drainage only(group I); catheter drainage and urokinase(group II); catheter drainage,urokinase and ozone(group III).Drainage was considered successful if empyema was resolved with closure of cavity,clinical symptoms were resolved,and need for any further surgical procedure was avoided.Success rate,length of stay(LOS),need for further surgery and hospital costs were compared between the three groups using the Kruskall-Wallis nonparametric test,with P < 0.05 considered significant.RESULTS Of the 209 patients with empyema,all catheters were placed successfully under CT guidance.Sixty-three patients were treated with catheters alone(group I),64 with catheters and urokinase(group II),and 82 with catheters,urokinase and ozone(group III).Group I,group II and group III had success rates of 62%,83% and 95% respectively(P < 0.05).Group I and groupII had statistically longer LOS(P < 0.05) and higher hospital costs(P < 0.05) compared to group III.There were statistically significant differences between the three groups when comparing patients who converted into further surgery.CONCLUSION The combination of chest tube drainage,urokinase and ozone is a safe and effective therapeutic modality in thoracic empyema. 展开更多
关键词 计算指导断层摄影术 导管排水 尿激 臭氧 蓄脓症
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The role of immune abnormality in depression and cardiovascular disease 预览
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作者 Ru-Hui LIU Jiang-Qi PAN +3 位作者 Xian-E TANG Bing LI Shang-Feng LIU Wen-Lin MA 《老年心脏病学杂志:英文版》 SCIE CAS CSCD 2017年第11期703-710,共8页
消沉和心血管的疾病(CVD ) 两个都是高度流行的混乱,并且一些证据证明有一个邪恶周期,连接主要消沉和 CVD。有有免疫力的畸形支撑的也成长的证据 CVD 和主要消沉的普通 pathophysiology。畸形包括下列:煽动性的标记的反常层次例如 in... 消沉和心血管的疾病(CVD ) 两个都是高度流行的混乱,并且一些证据证明有一个邪恶周期,连接主要消沉和 CVD。有有免疫力的畸形支撑的也成长的证据 CVD 和主要消沉的普通 pathophysiology。畸形包括下列:煽动性的标记的反常层次例如 interleukin-6 (IL-6 ) , interleukin-1 (IL-1 ) ,肿瘤坏死因素(TNF-) 和 interleukin-12 (IL-12 ) ;增加了尖锐阶段蛋白质,例如 C 反应的蛋白质,纤维蛋白原和 haptoglobin;并且反常补充因素。主要消沉和 CVD 病人举办的调查结果表演更大的有免疫力的畸形,可以增加压抑的症状和心血管的病理学的变化,并且可以有一种双向关系,因此,更未来的研究被需要得出结论。 展开更多
关键词 免疫力 心血管 反常 疾病 纤维蛋白原 CVD 调查结果 蛋白质
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Study on Preparation Technology of Taurine in Rice Peptide Feed 预览
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作者 Liang PENG Bing LI +1 位作者 Hui WANG Jianzhou TANG 《亚洲农业研究:英文版》 2017年第4期72-73,76共3页
With rice as experimental material,the multi-strain solid-state fermentation method was used to study the preparation technology of taurine,and the analysis of variance was employed to determine the optimal process of... With rice as experimental material,the multi-strain solid-state fermentation method was used to study the preparation technology of taurine,and the analysis of variance was employed to determine the optimal process of taurine preparation as follows: fermentation time(72h); amount of cysteinyl acid( 2. 5 g),amount of methionine( 2. 5 g); ratio of Bacillus subtilis YS-45 to yeast S-78 to Aspergillus niger PL-39( 1 ∶ 2 ∶ 1). Under the optimal process,the taurine content reached 117. 8 mg/g. 展开更多
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有序介孔Sn-SBA-15负载铂催化剂上丙烷脱氢性能的提高 预览
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作者 李冰 徐振新 +2 位作者 储伟 罗仕忠 敬方梨 《催化学报》 SCIE EI CAS CSCD 北大核心 2017年第4期726-735,共10页
丙烷脱氢制丙烯能够将低级烷烃转变成烯烃,是有效扩大丙烯来源的生产工艺.铂锡催化剂用于丙烷催化脱氢的主要缺点是稳定性差、选择性低,通过稳定锡的氧化态可以大大改善催化剂的脱氢性能及稳定性.本文采用一锅水热合成法制备了一系列高... 丙烷脱氢制丙烯能够将低级烷烃转变成烯烃,是有效扩大丙烯来源的生产工艺.铂锡催化剂用于丙烷催化脱氢的主要缺点是稳定性差、选择性低,通过稳定锡的氧化态可以大大改善催化剂的脱氢性能及稳定性.本文采用一锅水热合成法制备了一系列高比表面积具有高度有序介孔结构的Sn掺杂的Sn-SBA-15材料,并作为载体负载铂催化剂用于丙烷脱氢反应.同时利用传统浸渍法(IM)合成了Sn/SBA-15-IM材料作为对比.结合X射线衍射(XRD)、BET比表面积和孔体积测试、红外光谱(FT-IR)、X射线光电子能谱、H2程序升温脱附(H2-TPD)、热重分析(TGA)、扫描电镜和透射电镜等多种物理化学表征手段研究了Sn-SBA-15材料和催化剂的结构性质及其丙烷脱氢反应性能.XRD和BET比表面积和孔体积测试结果表明,水热合成法原位引入助剂Sn不影响载体SBA-15的有序孔道结构,同时能够保持较大的比表面积.传统浸渍法引入Sn会堵塞载体孔道,载体比表面积及孔道有序度下降.Sn掺杂进入SBA-15骨架能够增强Sn物种与载体的相互作用,有利于Sn物种在反应过程中保持氧化态,提高催化剂丙烷脱氢反应的活性及选择性.当Sn掺杂量增至2.0wt%时,Pt,Sn组分与载体之间的相互作用减弱,催化剂中Sn0物种所占比例增多,导致催化剂丙烷脱氢性能下降.在丙烷脱氢反应过程中,一锅法引入Sn的催化剂上反应活性和稳定性明显优于浸渍法引入Sn的催化剂.其中,Pt/0.5Sn-SBA-15催化剂表现出最优的丙烷脱氢性能,丙烷转化率为43.8%,丙烯选择性为98.5%. 展开更多
关键词 丙烷脱氢 一锅水热合成 Sn掺杂SBA-15 铂基催化剂 构效关系
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肠黏液屏障在肠道中的作用 预览 被引量:4
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作者 李冰 于岩波 《世界华人消化杂志》 CAS 2017年第19期1764-1771,共8页
肠黏液屏障是覆盖在肠上皮表面的由黏蛋白构成的凝胶型网状结构.MUC2是黏蛋白的主要成分,其特殊结构能保障黏液屏障的结构稳定性和抗性.杯状细胞能通过基础及调节分泌途径生成黏蛋白来维持和更新肠黏液层,肠道菌群也是黏液的组成、厚度... 肠黏液屏障是覆盖在肠上皮表面的由黏蛋白构成的凝胶型网状结构.MUC2是黏蛋白的主要成分,其特殊结构能保障黏液屏障的结构稳定性和抗性.杯状细胞能通过基础及调节分泌途径生成黏蛋白来维持和更新肠黏液层,肠道菌群也是黏液的组成、厚度及黏液屏障通透性功能形成的关键因素.肠黏液屏障能防止腔内细菌接触上皮,发挥抗感染作用,调节肠道免疫与外来刺激之间的平衡.而黏液屏障的结构和功能受损在感染性疾病、炎症性肠病、囊性纤维化、肿瘤等多种肠道疾病的发生发展中也起重要作用,或许会成为疾病治疗的新靶点. 展开更多
关键词 肠黏液屏障 黏蛋白 杯状细胞 肠道菌群
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Efficient removal of Co(Ⅱ) from aqueous solution by titanate sodium nanotubes 预览
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作者 Dong-Mei Li Fei-Ze Li +7 位作者 Jia-Li Liao Ji-Jun Yang Bing Li Yun-Ming Chen Yuan-You Yang Jin-Song Zhang Jun Tang Ning Liu 《核技术:英文版》 SCIE CAS CSCD 2016年第6期115-124,共10页
In this paper,a novel material for Co(Ⅱ)adsorption,titanate sodium nanotubes(Na2Ti2O5-NTs)were synthesized and characterized,and then they were used to remove Co(Ⅱ) from aqueous solution and compared with tita... In this paper,a novel material for Co(Ⅱ)adsorption,titanate sodium nanotubes(Na2Ti2O5-NTs)were synthesized and characterized,and then they were used to remove Co(Ⅱ) from aqueous solution and compared with titanic acid nanotubes(H2Ti2O5-NTs) and potassium hexatitanate whiskers(K2Ti6O13).The results showed that the adsorption of Co(Ⅱ) on the materials was dependent on p H values and was a spontaneous,endothermic process.Specifically,Na2Ti2O5-NTs exhibited much more efficient ability to adsorb Co(Ⅱ) from aqueous solution,with the maximum adsorption capacity of 85.25 mg/g.Furthermore,Na2Ti2O5-NTs could selectively adsorb Co(Ⅱ) from aqueous solution containing coexisting ions(Na+,K+,Mg2+,and Ca2+).The results suggested that Na2Ti2O5-NTs were potential effective adsorbents for removal of Co(Ⅱ) or cobalt-60 from wastewater. 展开更多
关键词 钛酸纳米管 钴(Ⅱ) 水溶液 CO(Ⅱ) 六钛酸钾晶须 新型材料 CO吸附
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Hydrocarbon Exploration in the South Yellow Sea Based on Airborne Gravity, China
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作者 Wenyong Li Yanxu Liu +1 位作者 Bing Li Feng Luo 《地球科学学刊:英文版》 SCIE CAS CSCD 2016年第4期686-698,共13页
Differences between the Cenozoic and pre-Cenozoic strata and structures in the middlesouth South Yellow Sea are analyzed using high-resolution airborne gravity data combined with data from offshore wells, seismic expl... Differences between the Cenozoic and pre-Cenozoic strata and structures in the middlesouth South Yellow Sea are analyzed using high-resolution airborne gravity data combined with data from offshore wells, seismic exploration and the regional geological background, using forward and inverse methods. We discuss why hydrocarbon exploration has so far failed in the South Yellow Sea, and put forward alternative future exploration plans. The results show that there are thick Cenozoic strata over Jurassic–Cretaceous continental strata in the southern basin of the South Yellow Sea, contrasted with thick Mid-Paleozoic marine strata preserved in the middle uplift area. In the mid-southern South Yellow Sea, airborne Bouguer gravity anomalies are fragmentized with scattered local anomalies. Many tensile normal faults and minor fault blocks occur in the Cenozoic strata. In contrast, reverse faults and nappe structures are found in pre-Cenozoic strata. The essential reasons for the lack of a breakthrough in hydrocarbon exploration are the complexity of geological structures, hydrocarbon accumulation environments, seismic-geologic conditions, and the difficulty of interpreting and understanding these features, rather than an imbalance of exploration framework. Hydrocarbon exploration should be targeted at Mid-Cenozoic continental strata, especially of Paleogene age, in the middle to southern parts of the South Yellow Sea. Special attention should be paid to the favorable structural belts SYI1, SYI2, SYI3 and SYI4 in the southern basin of the South Yellow Sea, where detailed seismic exploration or drilling should be carried out. Attention should also be given to Mid-Paleozoic marine strata in the middle uplift area of the South Yellow Sea. Key strategies that could lead to a hydrocarbon exploration breakthrough are improving exploration resolution, conducting detailed studies of fine structures, and accurately locating minor structures. 展开更多
关键词 南黄海南部盆地 油气勘探 重力数据 机载 新生代地层 区域地质背景 中国 布格重力异常
Improvement of catalytic stability for CO2 reforming of methane by copper promoted Ni-based catalyst derived from layered-double hydroxides 预览
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作者 Bing Li Zhenxin Xu +3 位作者 Fangli Jing Shizhong Luo Ning Wang Wei Chu 《能源化学:英文版》 SCIE EI CAS CSCD 2016年第6期1078-1085,
Copper-promoted nickel-based metal nanoparticles(NPs) with high dispersion and good thermal stability were derived from layered-double hydroxides(LDHs) precursors that were facilely developed by a coprecipitation ... Copper-promoted nickel-based metal nanoparticles(NPs) with high dispersion and good thermal stability were derived from layered-double hydroxides(LDHs) precursors that were facilely developed by a coprecipitation strategy.The copper-promoted Ni-based metal NPs catalysts were investigated for methane reforming with carbon dioxide to hydrogen and syngas.A series of characterization techniques including XRD,N2 adsorption and desorption,H2-TPR,XPS,CO2-TPD,TEM,TGA and in situ CH4-TPSR were utilized to determine the structure-function relationship for the obtained catalysts.The copper addition accelerated the catalyst reducibility as well as the methane activation,and made the Ni species form smaller NPs during both preparation and reaction by restricting the aggregation.However,with higher copper loading,the derived catalysts were less active during methane reforming with CO2 to syngas.It was confirmed that the catalyst with 1 wt%Cu additive gave the higher catalytic activity and remained stable during long time reaction with excellent resistance to coking and to sintering.Furthermore,the mean size of metal NPs changed minimally from 6.6 to 7.9 nm even after 80 h of time on stream at temperature as high as700℃ for this optimized catalyst.Therefore,this high dispersed anti-coking copper-promoted nickel catalyst derived from LDHs precursor could be prospective catalyst candidate for the efficient heterogeneous catalysis of sustainable CO2 conversion. 展开更多
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The scaling behavior of the second virial coefficient of linear and ring polymer
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作者 Bing Li Zhaoyan Sun +1 位作者 Lijia An Zhen-Gang Wang 《中国科学:化学英文版》 SCIE EI CAS CSCD 2016年第5期619-623,共5页
在相应线性聚合物的 theta 温度的戒指聚合物的第二个 virial 系数的可伸缩的行为(<sub > L </sub>) 被离开格子蒙特卡罗模拟调查。溶剂的效果被在聚合物单体之间的 pairwise 相互作用在这条途径建模。用伞采样,我们计算... 在相应线性聚合物的 theta 温度的戒指聚合物的第二个 virial 系数的可伸缩的行为(<sub > L </sub>) 被离开格子蒙特卡罗模拟调查。溶剂的效果被在聚合物单体之间的 pairwise 相互作用在这条途径建模。用伞采样,我们计算在二戒指聚合物以及第二 virial 系数 A 之间的有效潜在的 U (r) 在 <sub 的戒指聚合物的 <sub>2</sub>> 源于 3 身体相互作用和拓扑的限制的联合的 L </sub>, 。在关于链长度的有效潜力的力量的趋势显示出非单调的行为,不同地从仅仅由拓扑的限制引起了那。我们的模拟建议关于在 <sub 的戒指聚合物的 <sub>2</sub> 的可伸缩的行为有三政体 > L </sub> :统治政体,转线路政体,和统治政体的拓扑的限制的 3 身体相互作用。 展开更多
关键词 环状聚合物 线性聚合物 标度行为 维里系数 三体相互作用 拓扑约束 聚合物单体 约束控制
低分子肝素对肺癌的化疗增效及减少转移的临床研究 预览
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作者 李鹏 李冰 孙培龙 《中华临床医师杂志(电子版)》 CAS 2016年第4期127-128,共2页
目的 探讨低分子肝素对肺癌的化疗增效及减少转移的临床意义.方法 选取2010年12月至2012年5月我院收治的100例肺癌患者,随机分成两组,每组50例,分别是对照组和实验组,两组病例均采用DAE化疗方案,对照组仅行单纯的化疗治疗,而实验组在每... 目的 探讨低分子肝素对肺癌的化疗增效及减少转移的临床意义.方法 选取2010年12月至2012年5月我院收治的100例肺癌患者,随机分成两组,每组50例,分别是对照组和实验组,两组病例均采用DAE化疗方案,对照组仅行单纯的化疗治疗,而实验组在每1个化疗周期开始前1天起每天皮下注射1次低分子肝素.结果 实验组的1年整体生存率(66%)、2年整体生存率(24%)均大于对照组(38%、10%),具有较为明显的差异(P〈0.01);实验组与对照组总有效率不存在着统计学意义(P〉0.01);实验组在治疗后的D-二聚体水平出现了较为明显的降低(P〈0.01),而对照组在治疗后的D-二聚体水平降低不明显(P〉0.05).实验组的肺转移、腹壁转移、肝转移抑制作用明显好于对照组(P〈0.05).结论 低分子肝素既可提高肺癌患者的化疗效果,又可抑制减少肿瘤细胞转移. 展开更多
关键词 低分子肝素 肺癌 化疗增效 转移抑制
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血清环氧合酶2、单核细胞趋化蛋白-1与糖尿病足发生、发展的相关性研究 预览 被引量:4
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作者 杨岳 房辉 +4 位作者 张雅中 田金莉 孙雪玲 李冰 安彩霞 《中国现代医学杂志》 CAS 北大核心 2016年第21期104-108,共5页
目的 研究血清环氧合酶2(COX-2)和单核细胞趋化蛋白-1(MCP-1)与糖尿病足发生、发展的相关性。方法 筛选160例2型糖尿病患者,分为糖尿病足(DF)组,非糖尿病足(NDF)组,同期体检健康者60例为正常对照(NC)组,依据Wagner分级将DF组... 目的 研究血清环氧合酶2(COX-2)和单核细胞趋化蛋白-1(MCP-1)与糖尿病足发生、发展的相关性。方法 筛选160例2型糖尿病患者,分为糖尿病足(DF)组,非糖尿病足(NDF)组,同期体检健康者60例为正常对照(NC)组,依据Wagner分级将DF组分为轻型糖尿病足(LDF)组,重型糖尿病足(SDF)组,测定各组血清COX-2和MCP-1水平,并研究COX-2和MCP-1的相关性。结果 1NDF、LDF和SDF组血清COX-2水平均高于NC组(〈0.05),且LDF、SDF组高于NDF组(〈0.05),SDF组高于LDF组(〈0.001);2NDF、LDF和SDF组血清MCP-1水平均高于NC组(〈0.001),且LDF、SDF组高于NDF组(〈0.05);SDF组与LDF组比较,差异无统计学意义(〉0.05);3血清COX-2与MCP-1水平呈正相关(〈0.05);4多因素Logistic回归分析显示,COX-2、MCP-1、白细胞计数为DF发生、发展的独立危险因素(〈0.05)。结论 血清COX-2、MCP-1水平升高在DF发生、发展中发挥重要作用。 展开更多
关键词 糖尿病足 环氧合酶2 单核细胞趋化蛋白-1
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动物抗寄生虫药物的研究与应用进展 预览
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作者 张吉丽 司鸿飞 +2 位作者 李冰 周旭正 张继瑜 《农业科学与技术:英文版》 CAS 2016年第9期2127-2132,2156共7页
寄生虫病是目前危害人类和动物的最严重疾病之一。动物抗寄生虫类药物主要用于杀灭、驱除和预防动物寄生虫.主要分为抗蠕虫药、抗原虫药和杀虫药等。动物抗寄生虫药物对动物寄生虫病防控、畜牧业健康发展和公共卫生安全具有重要保障作... 寄生虫病是目前危害人类和动物的最严重疾病之一。动物抗寄生虫类药物主要用于杀灭、驱除和预防动物寄生虫.主要分为抗蠕虫药、抗原虫药和杀虫药等。动物抗寄生虫药物对动物寄生虫病防控、畜牧业健康发展和公共卫生安全具有重要保障作用。近年来,随着人们对寄生虫病重视程度的提升,抗寄生虫药物研发工作进展较快。掌握抗寄生虫药物的研究与应用进展对临床用药及基础研究具有重要意义。从抗寄生虫药物的研究与应用历史、现状、最新进展和今后的发展方向进行综述。 展开更多
关键词 动物 抗原虫药 抗蠕虫药 杀虫药 研究应用 展望
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光照对分蘖期水稻叶际及根系-培养液体系N2O和NOX(NO,NO2)排放的影响 预览
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作者 徐胜光 李冰 +5 位作者 刘佳妮 陈泽斌 余磊 赵凤 耿开友 王定康 《农业科学与技术:英文版》 CAS 2016年第3期633-641,共9页
[目的]该研究探讨光照对分蘖期水稻根、叶界面N2O和NOX排放的作用及其机制。[方法]试验在水培控氮、小型光控培养箱控光和同步测定条件下,探讨了不同光质、光强及光控处理对分蘖期水稻叶际及根系-培养液体系N_2O和NO_X排放的影响。[结果... [目的]该研究探讨光照对分蘖期水稻根、叶界面N2O和NOX排放的作用及其机制。[方法]试验在水培控氮、小型光控培养箱控光和同步测定条件下,探讨了不同光质、光强及光控处理对分蘖期水稻叶际及根系-培养液体系N_2O和NO_X排放的影响。[结果](1)在相同氮源(NH4NO3-N,90 mg/L)、日间光照为6 000、8 000lx条件下,分蘖期平均水稻叶际N_2O和NO排放速率分别为27.08、32.33μg/(pot·h)和0.114、0.057μg/(pot·h),分别占N2O和NO总排放的57.38%、58.65%和9.65%、4.52%,水稻叶际是N2O的重要排放源;(2)在光强(1 600 lx)一致条件下,LED黄、绿、白、红、蓝光处理的平均水稻叶际N2O排放速率分别为6.83、9.40、9.73、2.82和4.08μg/(pot·h),光X强较高的红(3 000 lx)、蓝光(2 500 lx)处理能同步抑制分蘖期水稻根、叶界面N2O的挥发(P〈0.01),LED红、白光有促进日间水稻叶际NO排放的作用,LED蓝光则有同步抑制水稻根、叶界面NO挥发的作用效果,但不同光控处理下水稻根、叶界面均无明显的NO2净排放作用;(3)0~8 000 lx范围内随着光照增强,水稻根部NO及根、叶界面N_2O排放同步增加,但高光强(6 000~8 000 lx)下水稻叶际NO排放显著大幅下降(P〈0.01)。[结论]水稻根、叶界面均以N_2O挥发为主;试验供氮水平下适度控制日间光强并同步增加红光、蓝光比例的技术,能同步抑制水稻根、叶界面氮氧化物的排放。 展开更多
关键词 光照 水稻 N2O NOX(NO、NO2) 排放
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Evaluation of the Effects of Standard Rescue Procedure on Severe Trauma Treatment in China
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作者 Xiao-Feng Yin Tian-Bing Wang +21 位作者 Pei-Xun Zhang Yu-Hui Kou Dian-Ying Zhang Kai Yu De-Cheng Lyu Mao-Zheng Liu Dong-Sheng Zhou Peng Zhang Jue-Hua Jing Wei-Wei Ge Li-Ying Cao Guo-Sheng Wang Shao-Jie Deng Weng-Hua Liu Mao Zhang Yong-An Xu Kun Zhang Bing Li Wei Wang Zhong-Li Gao Cheng-La Yi Bao-Guo Jiang 《中华医学杂志:英文版》 SCIE CAS CSCD 2015年第10期1301-1305,共5页
关键词 评估标准 标准程序 创伤 抢救 评价 救治 中国地理 响应时间
Ocular surface changes in type II diabetic patients with proliferative diabetic retinopathy
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作者 Yan Gao Yan Zhang +6 位作者 Yu-Sha Ru Xiao-Wu Wang Ji-Zhong Yang Chun-Hui Li Hong-Xing Wang Xiao-Rong Li Bing Li 《国际眼科杂志:英文版》 SCIE CAS 2015年第2期358-364,共7页
AIM: To detect and analyze the changes on ocular surface and tear function in type II diabetic patients with proliferative diabetic retinopathy(PDR), an advanced stage of diabetic retinopathy(DR), using conventional o... AIM: To detect and analyze the changes on ocular surface and tear function in type II diabetic patients with proliferative diabetic retinopathy(PDR), an advanced stage of diabetic retinopathy(DR), using conventional ophthalmic tests and the high-resolution laser scanning confocal microscopy.METHODS: Fifty-eight patients with type II diabetes were selected. Based on the diagnostic criteria and stage classification of DR, the patients were divided into the non-DR(NDR) group and the PDR group. Thirty-six patients with cataract but no other ocular and systemic disease were included as non-diabetic controls. All the patients were subjected to the conventional clinical tests of corneal sensitivity, Schirmer I test, and corneal fluorescein staining. The non-invasive tear film break-up time(NIBUT) and tear interferometry were conducted by a Tearscope Plus. The morphology of corneal epithelia and nerve fibers was examined using the high-resolution confocal microscopy.RESULTS: The NDR group exhibited significantly declined corneal sensitivity and Schirmer I test value, as compared to the non-diabetic controls(P 【0.001). The PDR group showed significantly reduced corneal sensitivity, Schirmer I test value, and NIBUT in comparison to the non-diabetic controls(P 【0.001).Corneal fluorescein staining revealed the progressively injured corneal epithelia in the PDR patients. Moreover,significant decrease in the corneal epithelial density andmorphological abnormalities in the corneal epithelia and nerve fibers were also observed in the PDR patients.CONCLUSION: Ocular surface changes, including blunted corneal sensitivity, reduced tear secretion, tear film dysfunction, progressive loss of corneal epithelia and degeneration of nerve fibers, are common in type II diabetic patients, particularly in the diabetic patients with PDR. The corneal sensitivity, fluorescein staining scores,and the density of corneal epithelial cells and nerve fibers in the diabetic patients correlate with the duration of diabetes. Therefore, ocular surf 展开更多
关键词 type II diabetes PROLIFERATIVE diabetic RETINOPATHY OCULAR surface corneal sensitivity CONFOCAL microscopy TEAR film BREAK-UP time
Greenhouse gas emission and its potential mitigation process from the waste sector in a large-scale exhibition 被引量:1
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作者 Ziyang Lou Bernd Bilitewski +4 位作者 Nanwen Zhu Xiaoli chai Bing Li Youcai Zhao Peter Otieno 《环境科学学报:英文版》 SCIE EI CAS CSCD 2015年第5期44-50,共7页
As one of the largest human activities, World Expo is an important source of anthropogenic Greenhouse Gas emission(GHG), and the GHG emission and other environmental impacts of the Expo Shanghai 2010, where around 59,... As one of the largest human activities, World Expo is an important source of anthropogenic Greenhouse Gas emission(GHG), and the GHG emission and other environmental impacts of the Expo Shanghai 2010, where around 59,397 tons of waste was generated during 184 Expo running days, were assessed by life cycle assessment(LCA). Two scenarios, i.e., the actual and expected figures of the waste sector, were assessed and compared, and 124.01 kg CO2-equivalent(CO2-eq.), 4.43 kg SO2-eq., 4.88 kg NO-3-eq., and 3509 m3 water per ton tourist waste were found to be released in terms of global warming(GW), acidification(AC),nutrient enrichment(NE) and spoiled groundwater resources(SGWR), respectively. The total GHG emission was around 3499 ton CO2-eq. from the waste sector in Expo Park, among which 86.47% was generated during the waste landfilling at the rate of 107.24 kg CO2-eq.,and CH4, CO and other hydrocarbons(HC) were the main contributors. If the waste sorting process had been implemented according to the plan scenario, around 497 ton CO2-eq.savings could have been attained. Unlike municipal solid waste, with more organic matter content, an incineration plant is more suitable for tourist waste disposal due to its high heating value, from the GHG reduction perspective.更多还原 展开更多
关键词 温室气体排放量 垃圾行业 城市固体废物 上海世博会 地下水资源 展览 生命周期评估 全球变暖问题
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