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基夫赛特熔炼过程中供氧方式的CFD模拟与优化 预览
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作者 李家栋 周萍 +3 位作者 廖舟 柴立元 Chenn Q.ZHOU 张岭 《中国有色金属学报:英文版》 SCIE EI CAS CSCD 2019年第7期1560-1568,共9页
通过数值模拟研究供氧方式对基夫赛特熔炼过程的影响。以中央喷射分配喷嘴的中央氧与侧氧质量流量比表示供氧方式,模拟质量流量比在 0.09~0.39 范围内的基夫赛特炉熔炼过程。结果表明,4 个中央喷射分配喷嘴下方区域为高效反应区。增大... 通过数值模拟研究供氧方式对基夫赛特熔炼过程的影响。以中央喷射分配喷嘴的中央氧与侧氧质量流量比表示供氧方式,模拟质量流量比在 0.09~0.39 范围内的基夫赛特炉熔炼过程。结果表明,4 个中央喷射分配喷嘴下方区域为高效反应区。增大中央氧流量可以改善颗粒与气体的混合状况,从而促进化学反应的进行,同时会缩短高效反应区;但是,由于喷嘴下颗粒柱的分散会使烟尘率增加。对于熔炼能力为 50000 kg/h 的基夫赛特炉,其最优的供氧方式为质量流量比取 0.31,在该工况下,炉料的化学反应可以充分进行,同时也保证较低的烟尘率。 展开更多
关键词 基夫赛特炉 中央喷射分散喷嘴 计算流体力学 中央氧 侧氧 最优化
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急性共同性内斜视的临床特点和非手术治疗的疗效评估
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作者 常枫 陈云辉 +3 位作者 陈晓 李梅 周萍 周和政 《中华眼视光学与视觉科学杂志》 CAS CSCD 2019年第2期147-152,共6页
目的:探讨急性共同性内斜视的临床特点,并评估非手术治疗的临床疗效。方法:回顾性系列病例研究。收集2015年8月至2017年11月在中国人民解放军武汉总医院眼科确诊的急性共同性内斜视患者18例。收集完整的临床资料,包括患者基本资料、神... 目的:探讨急性共同性内斜视的临床特点,并评估非手术治疗的临床疗效。方法:回顾性系列病例研究。收集2015年8月至2017年11月在中国人民解放军武汉总医院眼科确诊的急性共同性内斜视患者18例。收集完整的临床资料,包括患者基本资料、神经内科会诊情况,眼前节及眼底、远近斜视度、双眼视觉状态、头颅影像学检查。随访2~8个月,平均3.9个月。采用配对t检验进行统计分析。结果:患者年龄21~52(29.7±10.3)岁。戴镜看远斜视度为+9^△~+60^△(+36±13)^△;看近斜视度为+7^△~+45^△(+28±12)^△。看远斜视度大于看近,差异有统计学意义(t=6.32,P<0.001)。所有患者全身查体、中枢神经系统及内分泌系统检查均未见异常。在屈光矫正的基础上,使用底朝外三棱镜按照11的比例分别加到左右眼上。3例在随访期间不接受三棱镜矫正,改行斜视手术;其余患者均坚持戴镜,末次随访未诉戴镜看远复视明显,戴镜看远斜视度+6^△~+23^△,看近斜视度+4^△~+18^△。11例表示满意,4例认为一般,3例不满意。结论:急性共同性内斜视主要发生在近视人群,看远斜视度大于看近斜视度。三棱镜验配对于改善大部分急性共同性内斜视患者看远复视及斜视具有较好疗效,达到了治疗目的且避开了因患者处于发病早期斜视度数尚不稳定带来的手术治疗的风险,但长期疗效还需进一步观察。 展开更多
关键词 急性共同性内斜视 复视 三棱镜治疗
基于血栓弹力图抗栓治疗动脉粥样硬化性脑梗死的疗效分析 预览
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作者 葛中林 钱明月 +6 位作者 周萍 谭玉 伏兵 张照婷 张浩江 庄爱霞 陈皆春 《中国现代医学杂志》 CAS 2019年第11期78-83,共6页
目的探讨基于血栓弹力图(TEG)抗栓治疗急性动脉粥样硬化性脑梗死的疗效。方法选取连云港市第二人民医院收治的184例急性动脉粥样硬化性脑梗死(ACI)患者。随机分为:A组,阿司匹林抗栓治疗;B组,氯吡格雷抗栓治疗;C组,氯吡格雷联合阿司匹林... 目的探讨基于血栓弹力图(TEG)抗栓治疗急性动脉粥样硬化性脑梗死的疗效。方法选取连云港市第二人民医院收治的184例急性动脉粥样硬化性脑梗死(ACI)患者。随机分为:A组,阿司匹林抗栓治疗;B组,氯吡格雷抗栓治疗;C组,氯吡格雷联合阿司匹林抗栓治疗;D组,用血栓弹力图仪检测血小板抑制率,选择血小板抑制率高的抗栓药物治疗,每组46例。比较患者治疗前后神经功能缺损评分(NIHSS)、日常生活能力评分(ADL)、微栓子(MES)阳性率改善情况,统计卒中复发率及出血性事件的发生率。结果治疗后4组患者的NIHSS评分下降,而ADL评分提高(P<0.05),且治疗后C、D组NIHSS评分低于A、B组,ADL评分高于A、B组(P <0.05)。治疗后,C、D两组临床治疗有效率高于A组(P<0.0167)。治疗后,4组患者的MES阳性率均降低(P<0.05),且C组MES阳性率均低于A、B组(P<0.0167)。4组胃肠道不适、病死率比较,差异无统计学意义(P>0.05);治疗后C、D两组复发率低于A组(P <0.0167),但C、D两组间比较,差异无统计学意义(P>0.05)。出血事件B、D两组低于C组(P <0.0167)。结论采用基于血栓弹力图个体化治疗ACI的抗栓效果优于阿司匹林和氯吡格雷单用,同时能够有效降低双抗药物联合治疗带来的出血性事件风险。 展开更多
关键词 梗塞 大脑中动脉 血栓弹力图 氯吡格雷 阿司匹林 动脉粥样硬化 微栓子
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调节异常所致视力下降的临床分析
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作者 常枫 陈云辉 +3 位作者 陈晓 李梅 周萍 周和政 《中华眼视光学与视觉科学杂志》 CAS CSCD 2018年第9期541-545,共5页
目的:观察调节异常所致远或近视力下降的临床特点及临床疗效。方法:回顾性系列病例研究。收集2014年2月至2016年2月因视力下降在中国人民解放军武汉总医院眼科就诊,经验光和视功能检查确诊的因调节异常导致视力下降的25例患者的临床资料... 目的:观察调节异常所致远或近视力下降的临床特点及临床疗效。方法:回顾性系列病例研究。收集2014年2月至2016年2月因视力下降在中国人民解放军武汉总医院眼科就诊,经验光和视功能检查确诊的因调节异常导致视力下降的25例患者的临床资料,在屈光矫正的基础上联合睫状肌麻痹剂并行反转拍、调节交替训练和Brock线等视功能训练,分析其临床特点及治疗效果。采用配对t检验和Wilcoxon秩和检验进行统计分析。结果:①25例患者初诊时年龄6~24岁。4例外院诊断为“球后视神经炎”,1例外院配戴角膜塑形镜后效果欠佳就诊,2例准分子激光治疗近视术后视力下降,11例用眼过度后视力下降,7例仅因视力下降就诊。②疗效:基线裸眼远视力为4.19±0.34、等效球镜度(SE)为(-7.95±3.10)D、最佳矫正视力(BCVA)为4.28±0.32;21例给予托吡卡胺后SE为(-0.06±0.86)D、BCVA为4.43±0.15;14例应用阿托品凝胶后SE为(+1.24±0.84)D、BCVA为4.93±0.14。给予视功能训练3个月12次后,视功能项目指标较前改善,负相对调节(NRA)训练前后分别是+1.76±0.61、+2.49±0.15(t=-3.780,P<0.001),正相对调节(PRA)训练前后分别是-1.26±0.76、-2.43±0.34(t=3.977,P<0.001),调节灵敏度(Flipper拍)训练前后分别是0周/分(cpm)(负片通过困难)和10.6cpm(Z=-4.012,P<0.001)。随访中矫正视力及屈光度未见变化。结论:对于排除眼部器质性疾病的视力下降患者,要重视视功能检查;对调节异常所致视力下降患者,在传统治疗的基础上,加用视功能训练,可使视力恢复并稳定。 展开更多
关键词 调节异常 视功能检查 视功能训练
Effect of substrate curvature on thickness distribution of polydimethylsiloxane thin film in spin coating process
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作者 闫英 周平 +2 位作者 张尚雄 郭晓光 郭东明 《中国物理B:英文版》 SCIE EI CAS CSCD 2018年第6期479-487,共9页
卧龙河气田石炭系黄龙组储层分布特征研究 预览
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作者 周平 廖义沙 +2 位作者 刘冬玺 陈守春 陈智雍 《地球科学前沿(汉斯)》 2018年第2期295-302,共8页
石炭系黄龙组作为川东地区卧龙河气田最重要的产层之一,进行石炭系储层分布特征的研究对卧龙河气田的进一步勘探具有重要的指导意义。首先,通过卧龙河气田石炭系储层剖面对比分析可知:I类储层发育少且分布范围窄,II、III类储层纵向发育... 石炭系黄龙组作为川东地区卧龙河气田最重要的产层之一,进行石炭系储层分布特征的研究对卧龙河气田的进一步勘探具有重要的指导意义。首先,通过卧龙河气田石炭系储层剖面对比分析可知:I类储层发育少且分布范围窄,II、III类储层纵向发育厚度较大;其次,绘制的储层孔隙度及渗透率的等值线图分析表明,卧龙河气田石炭系黄龙组储层孔隙度主要介于4.5%~6.5%,渗透率主要在0.05~1.0 &#215;10?3 μm2之间变化,以低孔低渗为主,且储层孔隙度和渗透率均由构造轴部、陡带、高部位向边翼部逐渐减小;最后,研究和分析卧龙河气田石炭系不同级别储层等厚图得,II类和III类储层为主要储层类型且横向上连续性好,储层总厚度主要在4~16 m之间变化,靠近构造轴部和陡带部位的储层厚度在10 m以上,而离背斜轴部较远的各井储层厚度低于8 m。 展开更多
关键词 卧龙河气田 石炭系黄龙组 储层物性 储层级别 储层分布特征
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Anti-steatotic and anti-fibrotic effects of the KCa3.1 channel inhibitor, Senicapoc, in non-alcoholic liver disease 预览
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作者 Latha Paka David E Smith +10 位作者 Dawoon Jung Siobhan McCormack Ping Zhou Bin Duan Jing-Song Li Jiaqi Shi Yong-Jie Hao Kai Jiang Michael Yamin Itzhak D Goldberg Prakash Narayan 《世界胃肠病学杂志:英文版》 SCIE CAS 2017年第23期4181-4190,共10页
AIM To evaluate a calcium activated potassium channel(KCa3.1) inhibitor attenuates liver disease in models of non-alcoholic fatty liver disease(NAFLD).METHODS We have performed a series of in vitro and in vivo studies... AIM To evaluate a calcium activated potassium channel(KCa3.1) inhibitor attenuates liver disease in models of non-alcoholic fatty liver disease(NAFLD).METHODS We have performed a series of in vitro and in vivo studies using the KCa3.1 channel inhibitor, Senicapoc. Efficacy studies of Senicapoc were conducted in toxin-, thioacetamide(TAA) and high fat diet(HFD)-induced models of liver fibrosis in rats. Efficacy and pharmacodynamic effects of Senicapoc was determined through biomarkers of apoptosis, inflammation, steatosis and fibrosis. RESULTS Upregulation of KCa3.1 expression was recorded in TAA-induced and high fat diet-induced liver disease. Treatment with Senicapoc decreased palmitic aciddriven Hep G2 cell death.(P < 0.05 vs control) supporting the finding that Senicapoc reduces lipiddriven apoptosis in Hep G2 cell cultures. In animals fed a HFD for 6 wk, co-treatment with Senicapoc,(1) reduced non-alcoholic fatty liver disease(NAFLD) activity score(NAS)(0-8 scale),(2) decreased steatosis and(3) decreased hepatic lipid content(Oil Red O, P < 0.05 vs vehicle). Randomization of TAA animals and HFD fed animals to Senicapoc was associated with a decrease in liver fibrosis as evidenced by hydroxyproline and Masson’s trichrome staining(P < 0.05 vs vehicle). These results demonstrated that Senicapoc mitigates both steatosis and fibrosis in liver fibrosis models.CONCLUSION These data suggest that Senicapoc interrupts more than one node in progressive fatty liver disease by its anti-steatotic and anti-fibrotic activities, serving as a double-edged therapeutic sword. 展开更多
关键词 高胖的饮食 脂肪变性 纤维变性 KCa3.1 隧道 Senicapoc 发炎
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Chemistry and environmental significance of aerosols collected in the eastern Tianshan 预览
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作者 XiaoYu Zhang ShengJie Wang +4 位作者 Xin Zhang Ping Zhou Shuang Jin ZhongQin Li Nozomu Takeuchi 《寒旱区科学:英文版》 CSCD 2017年第5期455-466,共12页
Aerosol samples were collected at altitudes from 584 m a.s.l. to 3,804 m a.s.l. at seven sites of the eastern Tianshan. The occurrence, distribution, and possible sources of 47 trace metals-including alkali metals and... Aerosol samples were collected at altitudes from 584 m a.s.l. to 3,804 m a.s.l. at seven sites of the eastern Tianshan. The occurrence, distribution, and possible sources of 47 trace metals-including alkali metals and alkali earth metals, transition metals, lanthanoids, and heavy metals-were investigated. It was found that four sampling sites (Shuinichang, 1,691 m a.s.l.; Urumqi City, 809 m a.s.l.; FuKang Station, 584 m a.s.l.; and Bogeda Glacier No. 4, 3,613 m a.s.l.) were contaminated mainly by heavy metals. Other three high-altitude sites (Urumqi Glacier No. 1, 3,804 m a.s.l.; WangFeng road-maintenance station, 3,039 m a.s.l.; and Tianshan Glaciology Station, 2,135 m a.s.l.) were not polluted. The aerosol particles were clustered into two dominant types: crust-originated particles and pollution-derived particles. Aerosols from UG1, WF, and TGS were characterized by crust-originated particles such as clay, plagioclase, dolomite, alkali feldspar, and biotite; while those from SNC, Urumqi, FK, and BG4 were characterized by high content of Cl-rich particles, S-rich particles, and soot. The backward-trajectories results indicated that air masses arriving at SNC, Urumqi, FK, and BG4 were identified as the more polluted source, when compared to the short-range air mass transport from the North to UGI and WF. Relatively lower altitude, as well as terrain blocking, might be another important reason for the gradient difference in pollution influence among these seven places in the Urumqi River Basin. 展开更多
关键词 HEAVY-METAL POLLUTION AEROSOLS central ASIA
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Clinical and imaging features of subependymal giant cell astrocytoma:report of 20 cases
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作者 GuangHai Mei XiaoXia Liu +1 位作者 Ping Zhou Ming Shen 《中华神经外科杂志(英文)》 CSCD 2017年第2期67-73,共7页
不同进液方式下铜电解槽内电解液流动特性的评价 预览
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作者 周萍 马海博 +2 位作者 谢紫微 闫红杰 Chenn Q. ZHOU 《中国有色金属学报:英文版》 SCIE EI CAS CSCD 2017年第10期2282-2290,共9页
铜电解槽的进液口布置方式对极板间的流场有着显著的影响,而流场的分布决定电解过程中的电流分布。为了深入了解电解液在竖直极板间复杂的流动行为,以铜电解槽为研究对象,建立了针对“一端进液”、“底部中心进液”、“上侧交错进液... 铜电解槽的进液口布置方式对极板间的流场有着显著的影响,而流场的分布决定电解过程中的电流分布。为了深入了解电解液在竖直极板间复杂的流动行为,以铜电解槽为研究对象,建立了针对“一端进液”、“底部中心进液”、“上侧交错进液”和“底部交错进液”4种不同进液方式下电解槽内电解液的流动过程的三维计算流体动力学模型并进行数值模拟。结果表明:由于“底部中心进液”式电解槽中进液口的位置分布不均匀,其速度的极差较大,是交错进液时的4倍以上。另外,由于“底部交错进液”式电解槽内电解液的湍流强度较大,因此其体平均速度是“一端进液”式的4倍。综合来看,“底部交错进液”式电解槽能够将新鲜的电解液快速、均匀地补充到极板间,为提高电流密度和增加产能奠定了基础。 展开更多
关键词 铜电解精炼 进液口布置方式 流场均匀性 计算流体力学
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Microfocus small-angle X-ray scattering at SSRF BL16B1
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作者 滑文强 王玉柱 +4 位作者 周平 胡涛 李秀宏 边风刚 王劼 《中国物理C:英文版》 SCIE CAS CSCD 2017年第4期169-176,共8页
在测微计长度规模上提供高辉煌的 X 光检查横梁,在 SSRF BL16B1 的 SAXS 为学习小样品体积与一个 KB 镜子系统被建立了,或探查显微镜的形态学。萨克斯风管最小的 q 价值是有 1.5 牵椠 ? 桴 ? 湩整湲的流动的 0.1 nm <SUP>1</... 在测微计长度规模上提供高辉煌的 X 光检查横梁,在 SSRF BL16B1 的 SAXS 为学习小样品体积与一个 KB 镜子系统被建立了,或探查显微镜的形态学。萨克斯风管最小的 q 价值是有 1.5 牵椠 ? 桴 ? 湩整湲的流动的 0.1 nm <SUP>1</SUP> 展开更多
关键词 X射线小角散射 微焦点 SAXS 测试 X射线束 微米尺度 SSRF 微观形貌
Hepatocyte isolation from resected benign tissues: Results of a 5-year experience 预览
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作者 Fan-Ying Meng Li Liu +5 位作者 Jun Liu Chun-You Li Jian-Ping Wang Feng-Hui Yang Zhi-Shui Chen Ping Zhou 《世界胃肠病学杂志:英文版》 SCIE CAS 2016年第36期8178-8186,共9页
AIM To analyze retrospectively a 5-year experience of human hepatocyte isolation from resected liver tissues with benign disease.METHODS We established a method of modified four-step retrograde perfusion to isolate pr... AIM To analyze retrospectively a 5-year experience of human hepatocyte isolation from resected liver tissues with benign disease.METHODS We established a method of modified four-step retrograde perfusion to isolate primary human hepatocytes. Samples were collected from the resected livers of patients with intrahepatic duct calculi(n = 7) and liver hemangioma(n = 17). Only the samples weighing ≥ 15 g were considered suitable for hepatocyte isolation. By using the standard trypan blue exclusion technique, hepatocyte viability and yield were immediately determined after isolation.RESULTS Twenty-four liver specimens, weighing 15-42 g, were immediately taken from the margin of the removed samples and transferred to the laboratory for hepatocyte isolation. Warm ischemia time was 5-35 min and cold ischemia time was 15-45 min. For the 7 samples of intrahepatic duct calculi, the method resulted in a hepatocyte yield of 3.49 ± 2.31 × 10~6 hepatocytes/g liver, with 76.4% ± 10.7% viability. The 17 samples of liver hemangioma had significantly higher yield of cells(5.4 ± 1.71 × 10~6 cells/g vs 3.49 ± 2.31 × 10~6 cells/g, P < 0.05) than the samples of intrahepatic duct calculi. However, there seems to be no clear difference in cell viability(80.3% ± 9.67% vs 76.4% ± 10.7%, P > 0.05). We obtained a cell yield of 5.31 ± 1.87 × 10~6 hepatocytes/g liver when the samples weighed > 20 g. However, for the tissues weighing ≤ 20 g, a reduction in yield was found(3.08 ± 1.86 × 10~6 cells/g vs 5.31 ± 1.87 × 10~6 cells/g, P < 0.05).CONCLUSION Benign diseased livers are valuable sources for largenumber hepatocyte isolation. Our study represents the largest number of primary human hepatocytes isolated from resected specimens from patients with benign liver disease. We evaluated the effect of donor liver characteristics on cell isolation, and we found that samples of liver hemangioma can provide better results than intrahepatic duct calculi, in terms of cell yield. Furthermore, the size of the tissues can affect the outcom 展开更多
关键词 Human HEPATOCYTE Primary HEPATOCYTE Cell ISOLATION BENIGN liver disease HEPATOCYTE ISOLATION
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Evaluation of Burden Descent Model for Burden Distribution in Blast Furnace
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作者 Ping ZHOU Peng-yu SHI +3 位作者 Yan-po SONG Kai-le TANG Dong FU Chenn Q.ZHOU 《钢铁研究学报:英文版》 SCIE CAS CSCD 2016年第8期765-771,共7页
Mathematical models for burden descending process have been applied to obtain whole burden structures in blast furnace,whereas the accuracy of those burden descent models has not been sufficiently investigated.Special... Mathematical models for burden descending process have been applied to obtain whole burden structures in blast furnace,whereas the accuracy of those burden descent models has not been sufficiently investigated.Special evaluation method based on timeline burden profiles was established to quantitatively evaluate the error between experimental and modeled burden structures.Four existing burden descent models were utilized to describe the burden structure of a 1/20 scaled warm blast furnace.Input modeling conditions including initial burden profile,descending volumes in each time interval,and normalized descending velocity distribution were determined via special image processing technology.Modeled burden structures were evaluated combined with the published experimental data.It is found that all the models caught the main profile of the burden structure.Furthermore,the improved nonuniform descent model(Model IV)shows the highest level of precision especially when burden descends with unstable velocity distribution tendency.Meanwhile,the traditional nonuniform descent model(Model III)may also be desirable to model the burden descending process when the burden descending velocity presents a linear tendency.Finally,the uniform descent model(Model I)might be the first option for roughly predicting burden structure. 展开更多
关键词 数学模型 评价方法 负荷分配 高炉 炉料结构 建模条件 图像处理技术 速度分布
双辊铸轧和热轧处理AZ31B镁合金的动态拉伸性能 预览
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作者 Ping ZHOU Elmar BEEH +1 位作者 Meng WANG Horst E. FRIEDRICH 《中国有色金属学报:英文版》 SCIE EI CAS CSCD 2016年第11期2846-2857,共12页
研究双辊铸轧和热轧处理AZ31B 镁合金板材在室温和应变速率从0.001 s^-1 到375 s^-1 条件下的动态拉伸力学行为,以及力学性能与显微结构之间的关系.实验发现,该镁合金板材具有很强的初始基面纤维织构,并且在高应变速率条件下机械孪生成... 研究双辊铸轧和热轧处理AZ31B 镁合金板材在室温和应变速率从0.001 s^-1 到375 s^-1 条件下的动态拉伸力学行为,以及力学性能与显微结构之间的关系.实验发现,该镁合金板材具有很强的初始基面纤维织构,并且在高应变速率条件下机械孪生成为主要的变形机理.材料的屈服强度和拉伸极限强度随应变速率的提高而提高;然而,孪生诱导的软化效应导致应变强化指数随应变速率的提高而成比例地降低.在准静态拉伸条件下,断裂伸长率随应变速率的提高而明显地降低;而在动态拉伸条件下应变速率对断裂伸长率的影响却不明显.最后,应用扫描电镜对拉伸试样进行了断口形貌分析.分析结果表明,该加工状态下的AZ31B 镁合金板材的拉伸断裂是一种韧性与脆性混合断裂模式. 展开更多
关键词 镁合金 双辊铸轧 动态拉伸 应变速率敏感性 断口形貌
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Multivariable Dynamic Modeling for Molten Iron Quality Using Incremental Random Vector Functional-link Networks
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作者 Li ZHANG Ping ZHOU +2 位作者 He-da SONG Meng YUAN Tian-you CHAI 《钢铁研究学报:英文版》 SCIE EI CAS CSCD 2016年第11期1151-1159,共9页
Molten iron temperature as well as Si,P,and S contents is the most essential molten iron quality(MIQ)indices in the blast furnace(BF)ironmaking,which requires strict monitoring during the whole ironmaking production.H... Molten iron temperature as well as Si,P,and S contents is the most essential molten iron quality(MIQ)indices in the blast furnace(BF)ironmaking,which requires strict monitoring during the whole ironmaking production.However,these MIQ parameters are difficult to be directly measured online,and large-time delay exists in offline analysis through laboratory sampling.Focusing on the practical challenge,a data-driven modeling method was presented for the prediction of MIQ using the improved multivariable incremental random vector functional-link networks(M-I-RVFLNs).Compared with the conventional random vector functional-link networks(RVFLNs)and the online sequential RVFLNs,the M-I-RVFLNs have solved the problem of deciding the optimal number of hidden nodes and overcome the overfitting problems.Moreover,the proposed M-I-RVFLNs model has exhibited the potential for multivariable prediction of the MIQ and improved the terminal condition for the multiple-input multiple-output(MIMO)dynamic system,which is suitable for the BF ironmaking process in practice.Ultimately,industrial experiments and contrastive researches have been conducted on the BF No.2in Liuzhou Iron and Steel Group Co.Ltd.of China using the proposed method,and the results demonstrate that the established model produces better estimating accuracy than other MIQ modeling methods. 展开更多
Characteristics and source of aerosols at Shiyi Glacier,Qilian Mountains, China 预览
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作者 Zhang, XiaoYu Li, ZhongQin +1 位作者 Zhou, Ping Wang, ShengJie 《寒旱区科学:英文版》 CSCD 2016年第2期135-146,共12页
Aerosol samples were collected in the Shiyi Glacier, Qilian Mountains from July 24 to August 19, 2012 and analyzed formajor water-soluble ionic species (F^-, Cl^-, NO2^-, NO3^-, SO4^2-, Na^+, NH4^+, K^+, Mg^2+ an... Aerosol samples were collected in the Shiyi Glacier, Qilian Mountains from July 24 to August 19, 2012 and analyzed formajor water-soluble ionic species (F^-, Cl^-, NO2^-, NO3^-, SO4^2-, Na^+, NH4^+, K^+, Mg^2+ and Ca^2+) by ion chromatography.SO4^2- and NH4+ were the most abundant components of all the anions and cations, with average concentrations of 94.72and 54.26 neq/m^3, respectively, accounting for 34% and 20% of the total water-soluble ions analyzed. These mean ionconcentrations were generally comparable with the background conditions in remote sites of the Qilian Mountains, butwere much lower than those in certain cities in China. The particles were grouped into two dominant types according totheir morphology and EDX signal: Si-rich particles and Fe-rich particles. Backward air mass trajectory analysis suggestedthat inland cities may contribute some anthropogenic pollution to this glacier, while the arid and semi-arid regions ofcentral Asia were the primary sources of the mineral particles. 展开更多
关键词 AEROSOL GLACIER particles scanning electron MICROSCOPY (SEM)
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HP-hMG在卵巢次高反应患者体外受精周期中的临床应用效果 被引量:2
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作者 邢琼 徐千花 +6 位作者 魏兆莲 周平 徐玉萍 贺小进 向卉芬 吴欢 曹云霞 《生殖与避孕》 CAS CSCD 北大核心 2016年第1期32-37,共6页
目的:探讨卵巢次高反应患者体外受精.胚胎移植(invitrofertilization.embryotransfer,IVF—ET)周期应用高纯度尿促性素(HP.hMG,贺美奇)与重组人卵泡刺激素(r-FSH,果纳芬)促排卵的临床结局。方法:选择IVF—ET助孕的卵巢次... 目的:探讨卵巢次高反应患者体外受精.胚胎移植(invitrofertilization.embryotransfer,IVF—ET)周期应用高纯度尿促性素(HP.hMG,贺美奇)与重组人卵泡刺激素(r-FSH,果纳芬)促排卵的临床结局。方法:选择IVF—ET助孕的卵巢次高反应患者310例,随机分为A组和B组,分别给予r—FsH+HP.hMG(A组,n=124)和r-FSH(B组,咒=186)促排卵,统计促性腺激素(GIm)总用量、Gn使用天数、获卵数、受精率、卵裂率、优质胚胎率、临床妊娠率以及因卵巢过度刺激综合征(OHSS)周期取消率及ET后OHSS发生率。结果:患者的基本情况组间无统计学差异(P〉0.05),B组Gn使用天数明显多于A组(P〈0.05),Gn总用量明显多于A组(P〈0.05),hCG注射日E2、LH组问无统计学差异(P〉0.05),B组hCG注射日孕酮(P)值显著高于A组(P〈0.05);获卵数B组显著多于A组旧〈0.05),受精率、卵裂率、移植胚胎数组间无统计学差异(尸〉0.05),但优质胚胎率B组却显著低于A组(P〈0.05),移植患者临床妊娠率组间差异无统计学意义(P〉0.05),A组仅稍高于B组。A组预防OHSS周期取消率较B组明显下降(P〈0.05),B组移植患者OHSS发生率略高于A组(尸〉0.05)。结论:在卵巢次高反应患者人群中从启动目添加HP—hMG能改善胚胎质量,增加子宫内膜容受性,降低OHSS发生率。 展开更多
关键词 体外受精(IVF) 次高反应 重组人卵泡刺激素(r-FSH) 高纯度尿促性素(HP-hMG)
炎症性肠病肠外临床表现及对应治疗策略的研究进展 预览 被引量:5
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作者 张夏璐 李冶夫 周平 《世界华人消化杂志》 CAS 2016年第6期894-901,共8页
炎症性肠病(inflammatory bowel disease,I B D)是由于自身免疫系统紊乱引起免疫系统过度反应的慢性炎症性疾病,包括克罗恩病(Crohn's disease,CD)和溃疡性结肠炎(ulcerative colitis,UC).其病因未完全明确,且多发的肠外表现加重... 炎症性肠病(inflammatory bowel disease,I B D)是由于自身免疫系统紊乱引起免疫系统过度反应的慢性炎症性疾病,包括克罗恩病(Crohn's disease,CD)和溃疡性结肠炎(ulcerative colitis,UC).其病因未完全明确,且多发的肠外表现加重了IBD治疗的复杂性.骨关节炎(osteoarthritis,OA)是IBD中最常见的肠外表现,因其也是一种炎性疾病,所以我们设想,在关节炎关节形成过程中的炎症反应是否可引起IBD的发生,或加剧I B D的进展.作者在哈佛大学电子数据库中的Pub Med使用关键词"Crohn's disease、ulcerative colitis、arthritis、treatment"搜索近5年来此领域的文献,并筛选出与本篇综述相关的文献进行阅读,在此对IBD的肠外表现及治疗进行全面综述,并对骨关节炎与IBD之间的关系进行总结与设想. 展开更多
关键词 克罗恩病 溃疡性结肠炎 肠外表现 治疗 骨关节炎
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Morphological and microscopic characterization of five commonly-used testacean traditional Chinese medicines
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作者 Ying Xu Wei Song +2 位作者 Ping Zhou Ping Li Huijun Li 《药学学报:英文版》 CSCD 2015年第4期358-366,共9页
Testacean traditional Chinese medicine(TTCM), derived from the outer shell of sea or freshwater mollusks, is a special and important category of Chinese medicinal materials. To ensure the effective use of TTCM, a comp... Testacean traditional Chinese medicine(TTCM), derived from the outer shell of sea or freshwater mollusks, is a special and important category of Chinese medicinal materials. To ensure the effective use of TTCM, a comparative identification study was performed on five commonly-used testacean drugs, including Haliotidis Concha, Arcae Concha, Meretricis Concha, Ostreae Concha and Margaritifera Concha(Shijueming, Walengzi, Geqiao, Muli and Zhenzhumu in Chinese, respectively).Typical morphological photographs of the crude drugs were acquired, and the key microscopic characteristics of the derived powders under normal light microscope and polarized light microscope were summarized. The major results can be concluded as follows:(1) the original species involved in the five TTCMs could be distinguished by their respective interspecies morphological characteristics;(2) the key identification characteristics of the five powdered crude drugs were mainly crystal fragments, with the fragment features under both normal light and polarized light microscope providing powerful points for differentiating the five commonly-used testacean drugs. This study demonstrated that it is feasible to provide authentication for these five kinds of TTCMs by the combination of morphology with microscopy. 展开更多
Proportions of acetyl-histone-positive hepatocytes indicatethe functional status and prognosis of cirrhotic patients 预览
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作者 Ping Zhou Jie Xia +5 位作者 Yong-Jie Zhou Jun Wan Li Li Ji Bao Yu-Jun Shi Hong Bu 《世界胃肠病学杂志:英文版(电子版)》 SCIE CAS 2015年第21期6665-6674,共10页
AIM To investigate whether the proportions of acetylhistone-positive hepatocytes could be used as markersof deteriorating liver function.METHODS: In total, 611 cirrhotic cases from 3701patients who were diagnosed dur... AIM To investigate whether the proportions of acetylhistone-positive hepatocytes could be used as markersof deteriorating liver function.METHODS: In total, 611 cirrhotic cases from 3701patients who were diagnosed during the past 15years were screened, and 152 follow-up cases wereselected. Paraffin tissue microarray was preparedfor immunohistochemistry to examine acetyl-histoneexpression. The proportions of positive hepatocyteswere recorded, and their correlations to clinical andlaboratory indicators were analyzed statistically.RESULTS: The proportions of H2AK5ac+, H3K9/K14ac+and H3K27ac+ hepatocytes gradually increased withdeteriorating liver function and with increasing levelsof serum markers of liver injury. In the follow-upcases, patients with 〉 70% H2AK5ac+, H3K9/K14ac+ orH3K27ac+ hepatocytes had statistically lower survivalrates (P 〈 0.05). Furthermore, 〉 70% H2AK5ac+or H3K27ac+ hepatocytes were strong independentpredictors of overall survival (P 〈 0.05).CONCLUSION: The proportions of acetyl-histonepositivehepatocytes are closely associated with theliver function and prognosis of cirrhotic patients. 展开更多
关键词 HISTONE ACETYLATION Cirrhosis Liver function PROGNOSIS
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