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Design of diamond-shape photonic crystal fiber polarization filter based on surface plasma resonance effect 认领
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作者 张永霞 苑金辉 +7 位作者 屈玉玮 周娴 颜玢玢 吴强 王葵如 桑新柱 隆克平 余重秀 《中国物理B:英文版》 SCIE EI CAS CSCD 2020年第3期232-237,共6页
A novel plasmonic polarization filter based on the diamond-shape photonic crystal fiber(PCF) is proposed. The resonant coupling characteristics of the PCF polarization filter are investigated by the full-vector finite... A novel plasmonic polarization filter based on the diamond-shape photonic crystal fiber(PCF) is proposed. The resonant coupling characteristics of the PCF polarization filter are investigated by the full-vector finite-element method. By optimizing the geometric parameters of the PCF, when the fiber length is 5 mm, the polarization filter has a bandwidth of 990 nm and an extinction ratio(ER) of lower than -20 dB. Moreover, a single wavelength polarization filter can also be achieved, along with an ER of -279.78 dB at wavelength 1.55 μm. It is believed that the proposed PCF polarization filter will be very useful in laser and optical communication systems. 展开更多
关键词 PHOTONIC crystal fiber POLARIZATION filter EXTINCTION ratio
焦炉气加氢脱硫催化剂的研究 认领
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作者 赵国强 张华西 +3 位作者 王光永 吴强 王莉 应理 《乙醛醋酸化工》 2019年第4期6-12,24共8页
以高浓度CO、CO2焦炉气为原料,对催化剂CNDS-19分别进行了脱氧、脱烯烃、脱硫活性测试,并考察了催化剂抑制甲烷化副反应能力,确定了两段反应的实验条件,对催化剂CNDS-19进行了1000h寿命实验,结果表明:当一段反应温度260℃,空速2000h,二... 以高浓度CO、CO2焦炉气为原料,对催化剂CNDS-19分别进行了脱氧、脱烯烃、脱硫活性测试,并考察了催化剂抑制甲烷化副反应能力,确定了两段反应的实验条件,对催化剂CNDS-19进行了1000h寿命实验,结果表明:当一段反应温度260℃,空速2000h,二段反应温度360℃,空速1000h,压力2.5-2.8MPa时,催化剂加氢活性高,稳定性好,尾气噻吩含量始终维持在0.1ppm以下,总的碳基甲烷化率为1.94%。 展开更多
关键词 焦炉气 铁-钼 催化剂表征
P(VDF-TrFE)的铁电性能影响因素及研究现状 认领
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作者 吴强 宋玉洁 李俊 《高分子材料科学与工程》 EI CAS CSCD 北大核心 2019年第8期167-173,共7页
有机铁电聚合物P(VDF-TrFE)是聚偏氟乙烯(PVDF)的衍生物,因具有良好的铁电性能、光学性能、化学稳定性、柔性等优点,在电子器件领域有广阔的应用前景。文中综述了P(VDF-TrFE)的铁电性的根源以及一些影响铁电性能的因素——TrFE摩尔含量... 有机铁电聚合物P(VDF-TrFE)是聚偏氟乙烯(PVDF)的衍生物,因具有良好的铁电性能、光学性能、化学稳定性、柔性等优点,在电子器件领域有广阔的应用前景。文中综述了P(VDF-TrFE)的铁电性的根源以及一些影响铁电性能的因素——TrFE摩尔含量、薄膜厚度、退火温度、电极材料;综述了2种典型的薄膜制备方法和铁电薄膜在电子器件中的应用;最后根据其不足之处提出了有机铁电薄膜的研究方向和发展趋势。 展开更多
关键词 P(VDF-TrFE) 铁电薄膜 极化反转
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钴基纳米晶-氮掺杂碳纳米笼复合材料的构建与电化学储能性能研究 认领
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作者 麻青明 姚月坚 +6 位作者 闫明磊 赵杰 葛承宣 吴强 杨立军 王喜章 胡征 《中国科学:材料科学(英文版)》 SCIE EI CSCD 2019年第10期1393-1402,共10页
Co(OH)2、CoO和Co3O4等钴基化合物因具有高理论容量和赝电容性质而备受关注.但受限于活性表面积小、电荷传输缓慢等原因,钴基纳米材料的实际储能性能却有限.本文以我们前期开发的具有大比表面积、高导电性和微孔-介孔-大孔共存的分级结... Co(OH)2、CoO和Co3O4等钴基化合物因具有高理论容量和赝电容性质而备受关注.但受限于活性表面积小、电荷传输缓慢等原因,钴基纳米材料的实际储能性能却有限.本文以我们前期开发的具有大比表面积、高导电性和微孔-介孔-大孔共存的分级结构氮掺杂碳纳米笼(hNCNCs)为载体,成功构建了晶粒尺寸小、电荷转移快的系列钴基纳米晶-hNCNCs复合材料,有效地提高了活性材料的利用率.其中,Co(OH)2/hNCNCs在2 Ag ^-1下表现出1170 F g^-1的高比容量,基于活性物种Co(OH)2的比电容高达2214 Fg^-1,接近其理论值(2595 Fg^-1).研究发现,具有不同组成的Co(OH)2、CoO和Co3O4纳米晶通过相同的可逆氧化还原反应存储/释放电能.这种新的储能机理表明将碳基载体上的活性物种Co(OH)2转化为CoO或Co3O4的操作是非必要的,甚至可能损害其储能性能.本研究可为开发过渡金属化合物基高能量密度电极材料提供借鉴. 展开更多
关键词 CO(OH)2 过渡金属化合物 Co3O4 氧化还原反应 活性材料 高能量密度 活性物种 理论容量
Inflationary Cosmology with Quantum Gravitational Effects and Swampland Conjectures 认领
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作者 武强 朱涛 《理论物理通讯:英文版》 SCIE CAS CSCD 2019年第9期1115-1120,共6页
Recently proposed two swampland criteria that arising from string theory landscape leads to the important challenge of the realization of single-field inflationary models. Especially one of swampland criteria which im... Recently proposed two swampland criteria that arising from string theory landscape leads to the important challenge of the realization of single-field inflationary models. Especially one of swampland criteria which implies a large tensor-to-scalar ratio is strongly in tension with recent observational results. In this paper, we explore the possibility the swampland conjectures could be compatible with single-field inflationary scenarios if the effects due to the quantum theory of gravity are considered. We show that the quantum gravitational effects due to the nonlinear dispersion relation provides significant modifications on the amplitude of both the scalar and tensor perturbation spectra. Such modifications could be either raise or reduce the perturbation spectra depending on the values of the parameters in the nonlinear terms of the dispersion relations. Therefore, these effects can reduce the tensor-to-scalar ratio to a smaller value, which helps to relax the tension between the swampland conjecture and observational data. 展开更多
关键词 INFLATION QUANTUM GRAVITATIONAL effects swampland CONJECTURES uniform ASYMPTOTIC APPROXIMATION
我国发展面临能源与环境的双重约束分析及对策思考 认领 被引量:1
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作者 武强 涂坤 《科学通报》 EI CAS CSCD 北大核心 2019年第15期1535-1544,共10页
改革开放40年来,我国经济和社会发展取得了举世瞩目的成就,但经济社会高速发展与能源资源供给和生态环境的矛盾日益突出.随着能源生产与消费革命的推进,需要根据中国自身能源禀赋特征精准制定符合国情的能源战略,确保国家制定的宏伟发... 改革开放40年来,我国经济和社会发展取得了举世瞩目的成就,但经济社会高速发展与能源资源供给和生态环境的矛盾日益突出.随着能源生产与消费革命的推进,需要根据中国自身能源禀赋特征精准制定符合国情的能源战略,确保国家制定的宏伟发展目标所需求能源的有效供给和安全,保障经济社会可持续发展,满足人民日益增长的美好生活需要. 展开更多
关键词 能源与环境 经济社会可持续发展 社会发展 能源生产 生态环境 资源供给 能源战略 有效供给
The trend of change in catheter ablation versus antiarrhythmic drugs for the management of atrial fibrillation over time: a meta-analysis and meta-regression 认领
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作者 Wei LIU Qiang WU +1 位作者 Xiao-Jie YANG Jing Huang 《老年心脏病学杂志:英文版》 SCIE CAS CSCD 2018年第6期441-450,共10页
ObjectiveTo 在 time.MethodsThe 上与 atrial 纤维性颤动(AF ) 在病人为节奏控制与 antiarrhythmic 药治疗(ADT ) 相比在导管脱离的功效和安全评估变化的趋势联机数据库 PubMed 和 EMBASE 被在找相关研究。STATA 软件(版本 12.0 ) 被... ObjectiveTo 在 time.MethodsThe 上与 atrial 纤维性颤动(AF ) 在病人为节奏控制与 antiarrhythmic 药治疗(ADT ) 相比在导管脱离的功效和安全评估变化的趋势联机数据库 PubMed 和 EMBASE 被在找相关研究。STATA 软件(版本 12.0 ) 被用来执行元分析和 meta-regression.ResultsFifteen 包括有 AF 的 2249 个病人的使随机化的控制试用被识别。分享的结果证明那导管脱离与 ADT 相比在 AF 复发的风险与 52% 减小被联系[风险比率(RR )= 0.48, 95% 信心间隔(CI ) :0.40-0.57,我 <sup>2</sup>=70.7%) 。亚群分析证明那导管脱离在 2011 前与研究相比在 2011 以后在研究展出了更少的功效(RR = 0.61, 95% CI:0.54-0.68,我 <sup>2</sup>=9.3% 并且 RR = 0.34, 95% CI:0.24-0.47,我 <sup>2</sup>=69.9% ,分别地) ,并且安全结果更高显示出 1.08 褶层不利事件的发生(14.2% 对 7.3% ;RR = 1.08, 95% CI:1.04-1.13 ) 在在 2011 .ConclusionsCatheter 以后的研究,脱离看起来比为节奏控制的 ADT 优异。然而,更少的功效和不利事件的更高的率在 2011 前与研究相比在 2011 以后在研究被观察。 展开更多
关键词 纤维性 导管 回归 时间 颤动 管理 节奏控制 PUBMED
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现实核力Hartree-Fock Gamow基矢计算 认领
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作者 吴强 许甫荣 《科学通报》 EI CAS CSCD 北大核心 2018年第27期2876-2882,共7页
对远离稳定线弱束缚原子核性质的研究是当代核物理领域重要的热点之一.对于弱束缚核,如何自洽可靠地描述和处理束缚态和连续态之间的耦合是理论描述的关键问题,也是理论研究面临的一个挑战.一种较成功的方案是采用Gamow基,以相同的方式... 对远离稳定线弱束缚原子核性质的研究是当代核物理领域重要的热点之一.对于弱束缚核,如何自洽可靠地描述和处理束缚态和连续态之间的耦合是理论描述的关键问题,也是理论研究面临的一个挑战.一种较成功的方案是采用Gamow基,以相同的方式处理束缚态、共振态和散射态,来统一描述核结构和核反应性质.本文介绍了一种从现实核子-核子相互作用出发,从微观上自洽生成Hartree-Fock(HF)Gamow基的新方法.基于现实核力,首先在谐振子基下进行HF迭代,得到的HF势通过基转换解析延拓到复动量平面上,最后包含束缚态、共振态和散射态的Gamow基由求解复动量空间的HF方程得到.作为例子,基于手征核力N-3LO,核力利用V(low-k)方法重整化到动量截断Λ=2.1 fm^-1采用这种方法计算了-4He和^22O的HF单粒子共振态,并分析了计算的收敛性和有效性.还讨论了从散射态相移的计算得到共振态位置的方法,其得到^22O的单粒子共振态与复平面直接计算的结果一致.这种从现实核力得到HF Gamow基的方法计算量小,收敛快,得到的包含束缚态、共振态以及散射态的基,有望进一步应用于第一性原理的多体计算中来研究弱束缚核的性质. 展开更多
关键词 现实核力 共振态 连续谱 弱束缚
Boosting oxygen reduction activity of spinel CoFe2O4 by strong interaction with hierarchical nitrogen-doped carbon nanocages 认领
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作者 Hao Fan Lijun Yang +7 位作者 Yu Wang Xiali Zhang Qingsong Wu Renchao Che Meng Liu Qiang Wu Xizhang Wang Zheng Hu 《科学通报:英文版》 SCIE EI CSCD 2017年第20期1365-1372,共8页
The unique hierarchical nitrogen-doped carbon nanocages(h NCNC) are used as a new support to homogeneously immobilize spinel Co Fe_2O_4 nanoparticles by a facile solvothermal method. The so-constructed hierarchical Co... The unique hierarchical nitrogen-doped carbon nanocages(h NCNC) are used as a new support to homogeneously immobilize spinel Co Fe_2O_4 nanoparticles by a facile solvothermal method. The so-constructed hierarchical Co Fe_2O_4/h NCNC catalyst exhibits a high oxygen reduction activity with an onset potential of0.966 V and half-wave potential of 0.819 V versus reversible hydrogen electrode, far superior to the corresponding 0.846 and 0.742 V for its counterpart of Co Fe_2O_4/h CNC with undoped hierarchical carbon nanocages(h CNC) as the support, which locates at the top level for spinel-based catalysts to date.Consequently, the Co Fe_2O_4/h NCNC displays the superior performance to the Co Fe_2O_4/h CNC, when used as the cathode catalysts in the home-made Al-air batteries. X-ray photoelectron spectroscopy characterizations reveal the more charge transfer from Co Fe_2O_4 to h NCNC than to h CNC, indicating the stronger interaction between Co Fe_2O_4 and h NCNC due to the nitrogen participation. The enhanced interaction and hierarchical morphology favor the high dispersion and modification of electronic states for the active species as well as the mass transport during the oxygen reduction process, which plays a significant role in boosting the electrocatalytic performances. In addition, we noticed the high sensitivity of O 1 s spectrum to the particle size and chemical environment for spinel oxides, which is used as an indicator to understand the evolution of ORR activities for all the Co Fe_2O_4-related contrast catalysts. Accordingly,the well-defined structure-performance relationship is demonstrated by the combination of experimental characterizations with theoretical calculations. This study provides a promising strategy to develop efficient, inexpensive and durable oxygen reduction electrocatalysts by tuning the interaction between spinel metal oxides and the carbon-based supports. 展开更多
MiR-200a and miR-200b target PTEN to regulate the endometrial cancer cell growth in vitro 认领
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作者 Qiang Wu Ren-Lian Lu +1 位作者 Jing-Xiang Li Li-Jun Rong 《亚太热带医药杂志:英文版》 SCIE CAS 2017年第5期474-477,共4页
Objective:To study whether miR-200a and miR-200b target PTEN gene expression to regulate the endometrial cancer cell growth in vitro. Methods:Endometrial cancer cells ECC-1 were cultured and transfected with the miR-2... Objective:To study whether miR-200a and miR-200b target PTEN gene expression to regulate the endometrial cancer cell growth in vitro. Methods:Endometrial cancer cells ECC-1 were cultured and transfected with the miR-200a and miR-200b mimics and inhibitors as well as the negative control mimics and inhibitors,and then the cell proliferation activity as well as the expression of PTEN and downstream genes in cells was determined; after transfection of miR-200a and miR-200b mimics as well as PTEN-3’UTR luciferase report gene plasmids,the fluorescence activity of luciferase reporter gene was determined. Results:12 h,24 h and 48 h after transfection,the cell proliferation activity of miR-200a mimics group and miR-200b mimics group were significantly higher than those of NC mimics group while the cell proliferation activity of mi R-200 a inhibitor group and miR-200b inhibitor group were significantly lower than those of NC inhibitor group; 48 h after transfection,PTEN expression in cells and PTEN-3’UTR luciferase reporter gene fluorescence activity of miR-200 a mimics group and miR-200b mimics group were significantly lower than those of NC mimics group while p-PI3K and p-Akt expression were significantly higher than those of NC mimics group; PTEN expression in cells and PTEN-3’UTR luciferase reporter gene fluorescence activity of miR-200 inhibitor group and miR-200b inhibitor group were significantly higher than those of NC inhibitor group while p-PI3K and p-Akt expression were significantly lower than those of NC inhibitor group. Conclusion:miR-200 a and miR-200b can promote the endometrial cancer cell growth in vitro by targeted inhibition of PTEN gene expression. 展开更多
Banking deregulation and corporate tax avoidance 认领
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作者 Bill B.Francis Ning Ren Qiang Wu 《中国会计学刊:英文版》 2017年第2期87-104,共18页
We investigate whether tax avoidance substitutes for external financing. We exploit interstate banking deregulation as a quasi-external shock to examine whether firms engage in less tax avoidance after banking deregul... We investigate whether tax avoidance substitutes for external financing. We exploit interstate banking deregulation as a quasi-external shock to examine whether firms engage in less tax avoidance after banking deregulation, because of cheaper and easier access to credit from banks. We find no empirical evidence to support this substitutive relation, even for firms with higher financial constraints or firms with higher external financing dependence. 展开更多
Clinical study inpatient-reported outcomes after binocular implantation of aspheric intraocular lens of different negative spherical aberrations 认领
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作者 Ze-Quan Xu Xu-Hua Song +2 位作者 Wen-Zhe Li Yan Dou Qiang Wu 《亚太热带医药杂志:英文版》 SCIE CAS 2017年第7期771-774,共4页
Objective: To compare patient-reported outcomes after implantation of the ZA9003 intraocular lens(IOLs), or the MCX11 ASP IOLs or the spherical IOLs(HQ-201HEP). Methods: Prospective nonrandomized controlled trial was ... Objective: To compare patient-reported outcomes after implantation of the ZA9003 intraocular lens(IOLs), or the MCX11 ASP IOLs or the spherical IOLs(HQ-201HEP). Methods: Prospective nonrandomized controlled trial was used. A total of 105 patients(210 eyes) were divided into three groups according to the type of IOLs: ZA9003(35 patients, 70 eyes), MCX11 ASP(35 patients, 70 eyes) or HQ-201HEP(35 patients, 70 eyes). The main outcome was scores of Catquest nine-item short-form questionnaire. Additional outcome was best corrected visual acuities, spherical aberration(SA) and total higher-order aberrations(HOAs). Results: The global score was significantly lower in the spherical IOL group than the aspherical IOL group of-020 μm SA(P < 0.05) and the aspherical IOL group of-027 μm SA(P < 0.05), and no significant difference was found in the global score between the aspherical IOL group of-020 μm SA than the aspherical IOL group of-027 μm SA(P > 0.05). Significant differences were also found in question 2, question 5, question 6 and question 8 between the spherical IOLs and the aspherical IOLs. Conclusion: Implantation of an aspherical IOL could improve vision-related quality of life compared with a spherical IOL. However, there were no statistically significant differences in vision-related quality of life between aspheric IOLs with different negative spherical aberrations. 展开更多
Low-grade slightly elevated and polypoid colorectal adenomas display differential β-catenin-TCF/LEF activity, c-Myc, and cyclin D1 expression 认领
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作者 Tian-wen Yang Yun-han Gao +2 位作者 Sha-Ying Ma Qiang wu Zhong-fu Li 《世界胃肠病学杂志:英文版》 SCIE CAS 2017年第17期3066-3076,共11页
AIM To comparatively investigate the cellular and molecular characteristics of low-grade slightly elevated adenomas and polypoid adenomas.METHODS Colorectal tumors were collected from 24 patients with slightly elevate... AIM To comparatively investigate the cellular and molecular characteristics of low-grade slightly elevated adenomas and polypoid adenomas.METHODS Colorectal tumors were collected from 24 patients with slightly elevated adenomas and 23 patients with polypoid adenomas. five commonly mutated genes(APC, BRAf, KRAS, NRAS, and PIK3CA) were selected for mutational analysis. Paraffin-embedded tumor sections were used to calculate the apoptotic index(AI) and Ki-67 labeling index(KLI). Two pure colorectal epithelial cell lines were created by pooling the slightly elevated and polypoid tumors. western blots, luciferase assays for β-catenin-T-cell factor protein/β-cateninlymphoid enhancer factor(β-catenin-TCf/LEf)-driven transcriptional activity, and caspase activity assays were conducted on the two cell lines.RESULTS Slightly elevated lesions showed a significantly lower APC mutational frequency and a significantly higher KRAS mutational frequency(both P < 0.05). Slightly elevated lesions showed a significantly lower AI(P < 0.05). β-catenin and β-catenin-TCf/LEf-driven transcriptional activity was significantly upregulated in slightly elevated lesions(both P < 0.05). In slightly elevated lesions, c-Myc was significantly downregulated, while cyclin D1 was significantly upregulated(both P < 0.05). β-catenin-TCf/LEf-driven transcriptional activity was negatively correlated with c-Myc(ρ =-0.78). Slightly elevated lesions displayed significant Bcl-2 and Bcl-x L upregulation(both P < 0.05) along with significant decreases in caspase-9 and caspase-3 activity(both P < 0.05). c-Myc was negatively correlated with Bcl-2 and Bcl-x L(ρ =-0.74 and-0.78, respectively).CONCLUSION The lower apoptotic activity of low-grade slightly elevated adenomas can be partly attributed to upregulated β-catenin pathway activity and downregulated c-Myc expression. 展开更多
关键词 癌症 Colorectal 腺瘤 -CATENIN 非水虫息似
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射频消融治疗符合米兰标准的早期肝癌疗效分析 认领 被引量:3
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作者 崔芒芒 朱晓琳 +7 位作者 张倜 武强 崔云龙 李慧锴 李强 房锋 张伟 宋天强 《中国肿瘤临床》 CSCD 北大核心 2017年第11期539-543,共5页
目的:探讨射频消融治疗符合米兰标准的早期肝癌的疗效及预后危险因素.方法:回顾性分析天津医科大学肿瘤医院72例行射频消融治疗的符合米兰标准的早期肝癌患者病例,评估其术后恢复情况,分析复发率、生存率及预后危险因素.结果:72例患... 目的:探讨射频消融治疗符合米兰标准的早期肝癌的疗效及预后危险因素.方法:回顾性分析天津医科大学肿瘤医院72例行射频消融治疗的符合米兰标准的早期肝癌患者病例,评估其术后恢复情况,分析复发率、生存率及预后危险因素.结果:72例患者术后并发症轻微且恢复迅速,术后1、2、3年累积复发率分别为12.50%、20.83%和33.33%;1、2、3年累积生存率分别为93.06%、87.50%、79.17%.多因素分析提示肿瘤大小与复发密切相关,肿瘤大小与术前白蛋白水平是影响总生存的独立危险因素.结论:射频消融术治疗符合米兰标准的早期肝癌,近远期效果良好.肿瘤大小是复发的独立危险因素,肿瘤大小与术前白蛋白水平是影响总生存的重要因素. 展开更多
关键词 射频消融 米兰标准 肝癌 预后 危险因素
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我国利率市场化影响商业银行利差的机理研究:竞争效应还是风险效应 认领
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作者 巫强 顾以诺 黄艳秋 《南大商学评论》 CSSCI 2017年第2期19-34,共16页
我国渐进式利率市场化改革能否促进商业银行之间的竞争并减少其利差,这对于能否真正实现利率完全由市场供求决定极为重要。借鉴代理商模型(Model of Dealership),本文证明利率市场化会通过"竞争效应"和"风险效应"这两种渠道影响... 我国渐进式利率市场化改革能否促进商业银行之间的竞争并减少其利差,这对于能否真正实现利率完全由市场供求决定极为重要。借鉴代理商模型(Model of Dealership),本文证明利率市场化会通过"竞争效应"和"风险效应"这两种渠道影响商业银行利差,利率市场化对商业银行利差的整体影响取决于这两种效应的比较。本文还利用我国16家上市商业银行2010年第二季度至2015年第一季度的面板数据,估计两次重要利率市场化事件对商业银行利差的实际影响。结果发现,总体上我国利率市场化进程导致商业银行利差缩小,竞争效应超过风险效应,该结论对中小型商业银行也成立;但由于其优势市场地位,我国国有大型商业银行利差并未受到利率市场化的显著影响。 展开更多
关键词 利率市场化 利差 商业银行
Optic 认领
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作者 Yu-Lin Tao Li-Ming Tao +6 位作者 Zheng-Xuan Jiang He-Ting Liu Kun Liang Mo-Han Li Xuan-Sheng Zhu Yan-Lin Ren Bing-Jie Cui 《国际眼科杂志:英文版》 SCIE CAS 2017年第12期1883-1888,共6页
AIM: To evaluate the impact of spherical and aspherical intraocular lenses on the postoperative visual quality of age-related cataract patients using Optical Quality Analysis System(OQAS).METHODS: Seventy-four eyes wi... AIM: To evaluate the impact of spherical and aspherical intraocular lenses on the postoperative visual quality of age-related cataract patients using Optical Quality Analysis System(OQAS).METHODS: Seventy-four eyes with age-related cataracts were randomly divided into spherical and aspherical lens implantation groups. Best-corrected visual acuity(BCVA) was measured preoperatively, one day, one week, two weeks, one month and two months after surgery. A biometric systems analysis using the OQAS objective scattering index(OSI) was performed. RESULTS: There were no significant differences in visual acuity(P>0.05) before and after spherical and aspheric lens implantation. There was a negative linear correction between the OSI value and BCVA(r=-0.634, P=0.000), and positive corrections between the OSI value and the lens LOCUS III value of nucleus color(NC), nucleus opacity(NO), cortex(C) and posterior lens capsular(P)(r=0.704, P=0.000; r=0.514, P=0.000; r=0.276, P=0.020; r=0.417, P=0.000, respectively). OSI values of spherical vs aspherical lenses were 11.5±3.6 vs 11.8±3.4, 4.1±0.9 vs 3.3±0.8, 3.5±0.9 vs 2.7±0.7, 3.3±0.8 vs 2.6±0.7, 3.2±0.7 vs 2.5±0.8, and 3.2±0.8 vs 2.5±0.8 before and 1d, 1, 2wk, 1 and 2mo after surgery, respectively. All time points varied significantly(P<0.01) between the two groups.CONCLUSION: Aspherical IOLs does not significantly affect visual acuity compared with spherical IOLs. The OSI value, was significantly lower in the aspherical lens group compared with the spherical lens. This study shows that objective visual quality of aspheric IOLs is better than that of the spherical lens by means of OQAS biological measurement method. 展开更多
关键词 NERVE
Effect of hypoxia on expression of placental trophoblast cells SATB1 and β-catenin and its correlation with the pathogenesis of preeclampsia 认领
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作者 Qiang Wu Gang Wu Jing-Xiang Li 《亚太热带医药杂志:英文版》 SCIE CAS 2016年第6期548-552,共5页
Objective: To study the effect of hypoxia on the expression of placental trophoblast cells SATB1 and β-catenin and its correlation with the pathogenesis of preeclampsia. Methods: Trophoblastic cell lines HRT8/SVneo w... Objective: To study the effect of hypoxia on the expression of placental trophoblast cells SATB1 and β-catenin and its correlation with the pathogenesis of preeclampsia. Methods: Trophoblastic cell lines HRT8/SVneo were cultured, SATB1 and β-catenin expression and cell biological behavior were determined after hypoxia reoxygenation treatment; cell biological behavior and the expression of related genes were determined after the transfection of SATB1 and β-catenin siR NA; preeclampsia placenta and normal placenta tissues were collected and the expression of SATB1 and β-catenin were determined. Results: OD value, cell migration rate, m RNA contents of SATB1 and β-catenin of H/R group were significantly lower than those of Nor group, cell apoptosis rate was higher than that of Nor group and the number of invasive cells was less than that of Nor group; OD value and bcl-2 mRNA content of SATB1-siRNA group were lower than those of NC group; cell apoptosis rate as well as Bax, Caspase-3, caspase-6 and caspase-9 mRNA contents were higher than those of NC group; cell migration rate as well as CTSB, CTSD, MMP2 and MMP9 mRNA contents of β-catenin-siRNA group were lower than those of NC group; the number of invasive cells was less than that of NC group; the expression levels of SATB1 and β-catenin in preeclampsia placenta tissue were significantly lower than those in normal placenta tissue. Conclusions: Hypoxia can inhibit the expression of SATB1 and β-catenin in the pathogenesis of preeclampsia, which can affect the proliferation, apoptosis, migration and invasion of cells. 展开更多
关键词 PREECLAMPSIA PLACENTAL TROPHOBLAST SATB1 BETA-CATENIN
CRISPR Double Cutting through the Labyrinthine Architecture of 3D Genomes 认领
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作者 Haiyan Huang Qiang Wu 《遗传学报:英文版》 SCIE CAS CSCD 2016年第5期273-288,共16页
染色体被组织成订并且在分裂期间原子核的层次拓扑的结构。在每个染色体的分离领土以内,拓扑地联系了域(男孩) 在象基因规定那样的各种各样的原子进程起重要作用。在相对组成的边界分开的男孩内,远侧的元素通过象长途的提高倡导者相... 染色体被组织成订并且在分裂期间原子核的层次拓扑的结构。在每个染色体的分离领土以内,拓扑地联系了域(男孩) 在象基因规定那样的各种各样的原子进程起重要作用。在相对组成的边界分开的男孩内,远侧的元素通过象长途的提高倡导者相互作用那样的特定的循环染色质的接触调整他们的基因目标。高产量的定序研究揭示了百万个潜在的规章的 DNA 元素,它比更丰富仅仅 20,000 基因他们控制。编辑技术的最近出现的 CRISPR-Cas9 染色体启用了有效、精确基因并且染色体的 epigenetic 操作。多路、高产量的 CRISPR 能力便于基因的发现和解剖规章的元素。这里,我们为编辑的染色体, epigenome,和 3D 染色体描述 CRISPR 的应用,集中于与调查染色质男孩和发展基因规定的拓扑的合拢的 Cas9 和一双 sgRNAs 编辑的 CRISPR DNA 碎片。 展开更多
关键词 基因组 三维 DNA片段 建筑 迷宫 拓扑结构 编辑技术 基因调控
PCI techniques to aid implantation of CRT-D in a senior patient with persistent left superior vena cava 认领
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作者 Qiang WU Sha YU +1 位作者 Ya-Ping AN Bao-Lin CHEN 《老年心脏病学杂志:英文版》 SCIE CAS CSCD 2016年第7期639-642,共4页
关键词 心脏的再同步治疗 心失败 培植 Left  优异静脉 cava
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阿托伐他汀联合通心络及脑超声波干预易损斑块治疗缺血性脑血管病用药量分析 认领
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作者 王焕君 李严 +3 位作者 吴强 徐成龙 田蕊 李雪艳 《现代电生理学杂志》 2016年第2期77-80,86共5页
目的:探讨阿托伐他汀联合通心络及脑超声波干预易损斑块治疗缺血性脑血管病用药剂量。方法:选择缺血性脑血管病患者183例,采用随机数字表法将其分为3组,治疗A组62例,口服通心络4粒,每日3次,阿托伐他汀10 mg,每日1次,同时常规给予脑超... 目的:探讨阿托伐他汀联合通心络及脑超声波干预易损斑块治疗缺血性脑血管病用药剂量。方法:选择缺血性脑血管病患者183例,采用随机数字表法将其分为3组,治疗A组62例,口服通心络4粒,每日3次,阿托伐他汀10 mg,每日1次,同时常规给予脑超声波SUT-800型,超声输出频率800 k HZ,声强0.75~1.25 w/cm2治疗每日一次,每次30min,10 d一个疗程,间隔1周再进行第二个疗程,6个月观察疗效;治疗B组60例,口服通心络4粒,每日3次,阿托伐他汀20 mg,每日1次,另加脑超声波治疗同治疗A组,6个月后观察疗效;对照组61例:仅给予口服普通降脂药心脑清及脑超声波治疗。观察3组患者治疗前后血脂变化及脂肪斑块情况。结果:与治疗前比较,治疗A组和B组,血清TC、TG、LDL-C浓度下降,HDL-C浓度升高,颈动脉IMT明显变小或消失,易损斑块减少,稳定斑块明显增加,斑块长径及厚度积分明显变小(P〈0.05),对照组治疗前后血脂水平及板块性质、数目差异无统计学意义;治疗后,与对照组比较,治疗A组和B组血脂水平下降,斑块长泾及厚度积分变小(P〈0.05);与治疗A组比较,B组血脂水平及斑块情况差异无统计学意义。结论:阿托伐他汀联合通心络、脑超声波治疗能明显降低血脂水平,干预颈动脉脂肪斑块疗效明显,而且可以减少阿托伐他汀的用药剂量。 展开更多
关键词 通心络 阿托伐他汀 脑超声波 缺血性脑血管病
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