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The Error Analysis for the Remote Sensing of Water Vapor Data by Ground Based GPS in Tengchong, Yunnan Province 预览
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作者 Youlong Zhao Shunwu Zhou +2 位作者 Shuo Wang Jihua Sun Xin San 《地球科学和环境保护期刊(英文)》 2019年第9期231-245,共15页
Due to its special observation principle, GPS remote sensing atmospheric precipitation has the advantages of high time resolution and no weather conditions, and has been widely used in the research field of atmospheri... Due to its special observation principle, GPS remote sensing atmospheric precipitation has the advantages of high time resolution and no weather conditions, and has been widely used in the research field of atmospheric precipitation. Using ground-based GPS precipitate water vapor data (GPS-PWV) and radiosonde-precipitate water vapor data (RS-PWV) that integrated by Radiosonde data, the error between GPS-PWV and RS-PWV in Tengchong is analyzed on its distribution of wet and dry seasons, also the difference between 00:00 UTC and 12:00 UTC. Results show that the RMSE of GPS-PWV and RS-PWV on both 00:00 UTC and 12:00 UTC are less than 5 mm, they correspond with each other well and their correlation coefficient is above 0.95, additionally, GPS-PWV value is stable than RS-PWV value. On the whole, the value of GPS-PWV is slightly larger than RS-PWV. And the mean absolute error between them has higher values, 4.5 mm in 2011 and 4.7 mm in 2012 from May to October (local rainy season) and lower values, 2.8 mm in 2011 and 3.1 mm in 2012 in November to April (local dry season). Besides, the mean absolute error in the morning seems has a difference with its component in the evening. Specifically, it is bigger on 12:00 UTC than on 00:00 UTC and the mean absolute errors on 12:00 UTC of two years are 27% and 11% larger than errors on 00:00 UTC respectively. The correlation of mean absolute error and surface vapor pressure, surface air temperature is examined in this study as well. We achieved that the correlation coefficient between mean absolute error and surface vapor pressure, surface air temperature equals 0.32, 0.37 separately. Diverse characters of mean absolute error under different precipitation conditions are also discussed. The outcome is that the mean absolute error has a higher value on rainy days and a lower value on clear days. However, during the precipitation periods, it appears that the mean absolute error and the rainfall situation don’t agree with each other well, it is likely to change randomly. 展开更多
关键词 GPS-Derived PRECIPITATE WATER Vapor Tengchong RADIOSONDE WATER Vapor Mean ABSOLUTE Error Seasonal Characteristics
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基于径向基函数的线方法求解热传导方程 预览
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作者 王羽 谢焕田 +1 位作者 王硕 徐石玮 《应用数学进展》 2019年第1期64-70,共7页
文章借助线方法求解热传导方程的初边值问题,该方法是基于径向基函数的真正无网格方法,数值实验的结果表明了该方法的可行性和有效性。
关键词 线方法 热方程 径向基函数 无网格方法
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外周血游离DNA的动态变化预测TKI治疗EGFR突变肺腺癌患者的疗效
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作者 宋雨光 王硕 +6 位作者 赵艳杰 姜妮 乔国良 赵静 邸岩 王小莉 任军 《中国肺癌杂志》 CAS CSCD 北大核心 2019年第9期568-573,共6页
背景与目的有表皮生长因子受体(epidermal growth factor receptor, EGFR)突变的非小细胞肺腺癌,患者在给予酪氨酸激酶抑制剂(tyrosine kinase inhibitors, TKIs)的治疗中获得非常好的疗效,但绝大多数患者都会出现耐药,使得发现出现耐... 背景与目的有表皮生长因子受体(epidermal growth factor receptor, EGFR)突变的非小细胞肺腺癌,患者在给予酪氨酸激酶抑制剂(tyrosine kinase inhibitors, TKIs)的治疗中获得非常好的疗效,但绝大多数患者都会出现耐药,使得发现出现耐药的时间及可能耐药机制的检测有着越来越大的意义,目前二代基因测序方法(next generation sequencing, NGS)的出现使其成为可能。本文拟通过研究靶向治疗前后有EGFR突变的非小细胞肺癌循环肿瘤DNA(circulating tumor DNA, ctDNA)突变频率及突变谱的变化来监测靶向治疗效果。方法本中心入组22例通过组织活检或外周血ctDNA检查出EGFR突变的患者,分别于治疗前、服用TKI后2个月及临床进展时收集患者的外周血8mL行ctDNA测序。结果 EGFR敏感突变患者应用靶向药物治疗效果显著,EGFR敏感突变的患者在用TKI治疗后,相比治疗前突变基因突变丰度明显降低(P=0.015,3);患者的中位无进展生存期较长(无进展生存时间=390 d)。同时我们发现伴随TP53基因突变时应用针对EGFR敏感突变的靶向药物治疗效果欠佳(中位无进展生存时间为120 d vs 630 d,P=0.000,2)。结论 EGFR敏感突变的患者在用TKI治疗后,突变基因突变丰度明显降低的患者的生存期更长(P<0.05),突变丰度减低不明显或伴有其他突变者预示着TKI耐药。 展开更多
关键词 肺肿瘤 表皮生长因子受体 酪氨酸激酶抑制剂 二代基因测序 循环肿瘤DNA
分离膜疏水化改性技术的研究进展 预览
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作者 李红宾 石文英 +3 位作者 王朔 杜启云 张海霞 覃小红 《高分子材料科学与工程》 EI CAS CSCD 北大核心 2019年第6期165-174,共10页
不同于常规亲水性分离膜,疏水性分离膜以其特殊的疏水性及选择分离特性而广泛应用于膜蒸馏、气液分离、气体分离以及一些特种分离领域,在膜分离技术中有不可替代的地位。如何赋予分离膜优异的疏水性能一直是疏水性分离膜研究的主要方向... 不同于常规亲水性分离膜,疏水性分离膜以其特殊的疏水性及选择分离特性而广泛应用于膜蒸馏、气液分离、气体分离以及一些特种分离领域,在膜分离技术中有不可替代的地位。如何赋予分离膜优异的疏水性能一直是疏水性分离膜研究的主要方向之一。文中对近十年来国内外分离膜疏水化改性技术进行了综述,并详细介绍了疏水性增强物质及各种疏水化改性方法的优缺点及研究现状。最后提出目前分离膜疏水化改性技术中需要解决的问题并对其发展前景进行了展望。 展开更多
关键词 疏水化改性 分离膜 化学接枝 共混 涂层
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The working road map in a neurosurgical Hybrid Angio-Surgical suite————development and practice of a neurosurgical Hybrid Angio-Surgical suite
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作者 Zeguang Ren Shuo Wang +8 位作者 Kaya Xu Maxim Mokin Yuanli Zhao Yong Cao Jia Wang Hancheng Qiu Siviero Agazzi Harry van Loveren Jizong Zhao 《中华神经外科杂志(英文)》 CSCD 2018年第2期94-99,共6页
Background: The concept of a Hybrid Angio-Surgical Suite (HASS) has emerged as a solution to the complexity of cerebrovascular surgery and the need for immediate intraoperative feedback. When to use it, what cases are... Background: The concept of a Hybrid Angio-Surgical Suite (HASS) has emerged as a solution to the complexity of cerebrovascular surgery and the need for immediate intraoperative feedback. When to use it, what cases are suitable for its use, who can use it and how to use it remain debatable. Objective: Provide the information regarding the application of the HASS for hospital, neurosurgeon and interventionalist. Methods: We review the literatures of case reports and studies on the use of the hybrid angio-sugical suite along with application of HASS in our own practice. Results: Indications for using HASS on different types of cerebral vascular disease, including cerebral aneurysm, AVM, DAVF, carotid and vertebral stenosis/occlusion, are addressed. The application of HASS for other non-cerebral vascular diseases, such as trauma, spine and skullbase cases, is reviewed and discussed. Conclusion: HASS has made many surgical procedures safer and many difficult or previously untreatable conditions much more tractable and cost-effective. Other than used in cerebral vascular disease, HASS has much more applications, such as trauma, spine and other neurosurgical diseases. 展开更多
关键词 HYBRID ANGIOGRAM Operating room CEREBROVASCULAR
Context-Oriented Multi-RAT User Association and Resource Allocation with Triple Decision in 5G Heterogeneous Networks 预览
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《中国通信:英文版》 SCIE CSCD 2018年第4期72-85,共14页
关键词 资源分配策略 上下文 老鼠 网络 用户 协会 异构 存取技术
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Deep cleaning of a metallurgical zinc leaching residue and recovery of valuable metals 预览
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作者 Peng Xing Bao-zhong Ma +6 位作者 Peng Zeng Cheng-yan Wang Ling Wang Yong-lu Zhang Yong-qiang Chen Shuo Wang Qiu-yin Wang 《矿物冶金与材料学报:英文版》 SCIE EI CAS CSCD 2017年第11期1217-1227,共11页
Huge quantities of zinc leaching residues (ZLRs) generated from zinc production are dumped continuously around the world and pose a potential environmental threat because of their considerable amounts of entrained hea... Huge quantities of zinc leaching residues (ZLRs) generated from zinc production are dumped continuously around the world and pose a potential environmental threat because of their considerable amounts of entrained heavy metals (mainly lead). Most ZLRs have not been properly treated and the valuable metals in them have not yet been effectively recovered. Herein, the deep cleaning of a ZLR and recovery of valuable metals via a hydrometallurgical route were investigated. The cleaning process consists of two essential stages: acid leaching followed by calcium chloride leaching. The optimum conditions for extracting zinc, copper, and indium by acid leaching were a sulfuric acid concentration of 200 g·L?1, a liquid/solid ratio of 4:1 (mL/g), a leaching time of 2 h, and a temperature of 90°C. For lead and silver extractions, the optimum conditions were a calcium chloride concentration of 400 g·L?1, a pH value of 1.0, a leaching time of 1 h, and a temperature of 30°C. After calcium chloride leaching, silver and lead were extracted out and the lead was finally recovered as electrolytic lead by electrowinning. The anglesite phase, which poses the greatest potential environmental hazard, was removed from the ZLR after deep cleaning, thus reducing the cost of environmental management of ZLRs. The treatment of chlorine and spent electrolyte generated in the process was discussed. 展开更多
关键词 DEEP CLEANING ZINC LEACHING RESIDUE ZINC lead LEACHING ELECTROWINNING
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A catalogue of Burmite inclusions
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作者 Mingxia Guo Lida Xing +4 位作者 Bo Wang Weiwei Zhang Shuo Wang Aimin Shi Ming Bai 《动物分类学报:英文版》 CSCD 2017年第3期249-379,共131页
Burmite(Burmese amber) from the Hukawng Valley in northern Myanmar is a remarkable valuable and obviously the most important amber for studying terrestrial diversity in the mid-Cretaceous. The diversity of Burmite inc... Burmite(Burmese amber) from the Hukawng Valley in northern Myanmar is a remarkable valuable and obviously the most important amber for studying terrestrial diversity in the mid-Cretaceous. The diversity of Burmite inclusions is very high and many new taxa were found, including new order, new family/subfamily, and new genus. Till the end of 2016, 14 phyla, 21 classes, 65 orders, 279 families, 515 genera and 643 species of organisms are recorded, which are summized and complied in this catalogue. Among them, 587 species are arthropods. In addtion, the specimens which can not be identified into species are also listed in the paper. The information on type specimens, other materials, host and deposition of types are provided. 展开更多
关键词 缅甸 琥珀 目录 沉积类型 白垩纪中期 节肢动物 多样性 内含物
Analysis of gene expression in intracranial aneurysms
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作者 Jia Wang Lanbing Yu +2 位作者 Dong Zhang Shuo Wang Jizong Zhao 《中华神经外科杂志(英文)》 CSCD 2017年第4期219-223,共5页
Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-κB/MLCK pathway in a mouse endotoxemia model 预览
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作者 Jie Han Ji-Hong Li +5 位作者 Guang Bai Guo-Shun Shen Jing Chen Jia-Nan Liu Shuo Wang Xian-Jun Liu 《世界胃肠病学杂志:英文版》 SCIE CAS 2017年第12期2175-2184,共10页
AIM To examine the effects of Acanthopanax senticosus polysaccharides(ASPS) on intestinal tight junction(TJ) disruption and nuclear factor-kappa B(NF-κB)/myosin light chain kinase(MLCK) activation in endotoxemia.METH... AIM To examine the effects of Acanthopanax senticosus polysaccharides(ASPS) on intestinal tight junction(TJ) disruption and nuclear factor-kappa B(NF-κB)/myosin light chain kinase(MLCK) activation in endotoxemia.METHODS BALB/C mice(6-8-weeks-old) received continuous intragastric gavage of ASPS for 7 d before injection of lipopolysaccharide(LPS), or received ASPS once after LPS injection. Blood and intestinal mucosal samples were collected 6 h after LPS challenge. Clinical symptoms, histological injury, intestinal permeability,TJ ultrastructure, and TJ protein expression were determined.RESULTS Compared with mice in the LPS group, pretreatment with ASPS improved clinical and histological scores by 390.9%(P < 0.05) and 57.89%(P < 0.05), respectively, and gut permeability change in endotoxemic mice was shown by a 61.93% reduction in reduced leakage of fluorescein isothiocyanate-dextran 6 h after LPS injection(P < 0.05). ASPS pretreatment also prevented LPS-induced TJ ultrastructure breakdown supported by increased electron dense materials between adjoining cells, sustained redistribution and expression of occludin(0.597 ± 0.027 vs 0.103 ± 0.009, P < 0.05) and zonula occludens-1(0.507 ± 0.032 vs 0.125 ± 0.019, P < 0.05), and suppressed activation of the NF-κB/MLCK pathway indicated by reduced expression of NF-κB, phospho-inhibitor kappa B-alpha, MLCK and phospho-myosin light-chain-2 by 16.06%(P < 0.05), 54.31%(P < 0.05), 66.10%(P < 0.05) and 64.82%(P < 0.05), respectively. CONCLUSION ASPS pretreatment may be associated with inhibition of the NF-κB/MLCK pathway and concomitant amelioration of LPS-induced TJ dysfunction of intestinal epithelium in endotoxemia. 展开更多
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Electraesalopsis beuteli gen. & sp. nov., the first lucanid beetle from the Cretaceous Burmese amber(Coleoptera: Scarabaeoidea)
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作者 Tengfei Qiu Yuanyuan Lu +3 位作者 Weiwei Zhang Shuo Wang Yuxia Yang Ming Bai 《动物分类学报:英文版》 CSCD 2017年第3期390-394,共5页
Absract The first stag beetle found in Cretaceous Myanmar amber, Electraesalopsis beuteli Bai, Zhang & Qiu gen. & sp. nov., is described and illustrated on the basis of one well-preserved specimen. This specim... Absract The first stag beetle found in Cretaceous Myanmar amber, Electraesalopsis beuteli Bai, Zhang & Qiu gen. & sp. nov., is described and illustrated on the basis of one well-preserved specimen. This specimen provides more detailed morphological characters compared with compression fossils, e.g. the highly setose antennae and the punctured elytra. However, the systematic position of the new genus is still questionable and we provisionally place it as Lucanidae incertae sedis. In addition, the discovery of Electraesalopsis Bai, Zhang & Qiu gen. nov. also indicates that there is very high biodiversity in Burmese amber. The new discoveries in future studies on Burmese amber will provide more information and improve our knowledge of biogeography and early evolution of the Lucanidae. 展开更多
关键词 鞘翅目 白垩纪 琥珀 缅甸 金龟总科 甲虫 分类位置 形态学特征
Human brain arteriovenous malformation:an analysis of differential expressed genes
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作者 Xing Liu Guolu Meng +7 位作者 Tengfei Yu Xiangjiang Lin Liwei Zhang Junting Zhang Zhen Wu Shengze Deng Shuo Wang Jizong Zhao 《中华神经外科杂志(英文)》 CSCD 2017年第1期21-26,共6页
^18F-FDG PET对睾丸生殖细胞肿瘤化疗后肿瘤残留的准确性判断 预览 被引量:2
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作者 王硕 杜鹏 +4 位作者 汤星星 安超 赵强 张宁 杨勇 《中国肿瘤临床》 CSCD 北大核心 2017年第12期608-611,共4页
目的:探讨睾丸生殖细胞肿瘤化疗后^18F-FDG PET对腹膜后残留病灶的准确性判断。方法:回顾性分析2014年2月至2016年12月北京大学肿瘤医院泌尿外科16例睾丸生殖肿瘤伴腹膜后淋巴结转移患者的资料,4-6个疗程的博来霉素+顺铂+依托泊苷(... 目的:探讨睾丸生殖细胞肿瘤化疗后^18F-FDG PET对腹膜后残留病灶的准确性判断。方法:回顾性分析2014年2月至2016年12月北京大学肿瘤医院泌尿外科16例睾丸生殖肿瘤伴腹膜后淋巴结转移患者的资料,4-6个疗程的博来霉素+顺铂+依托泊苷(BEP)化疗后行腹部CT检查,所有患者的腹膜后肿块直径〉2 cm。^18F-FDG PET检查后行腹膜后淋巴结清扫术,并进行术后病理与术前^18F-FDG PET结果比较。结果:16例患者中10例^18F-FDG PET结果阳性,其中5例术后病理存在肿瘤残留、5例无肿瘤残留组织;6例^18F-FDG PET结果为阴性,2例术后病理肿瘤残留患者均为成熟畸胎瘤、4例无肿瘤组织残留。^18F-FDG PET的准确率为56.25%(9/16),灵敏度为71.42%(5/7),特异度为44.44%(4/9),阳性预测率为50.00%(5/10),阴性预测率为66.67%(4/6)。结论:^18F-FDG PET灵敏度较高,但多种因素会影响^18F-FDG PET结果的准确性,成熟畸胎瘤易造成^18F-FDG PET的假阴性,大量炎性组织易造成^18F-FDG PET假阳性,需结合多种检查提高结果准确性。 展开更多
关键词 ^18F-FDG PET 睾丸生殖细胞肿瘤 腹膜后淋巴结清扫术
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扭矩作用下薄壁双闭室结构的隔板应力分析 预览
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作者 王硕 张铮 黄裕梁 《力学研究》 2017年第2期72-81,共10页
本文对薄壁双闭室结构隔板上的应力分布情况进行了研究。首先对结构型式进行简化,建立有限元模型,然后用ANSYS软件进行计算,揭示了多闭室结构隔板的应力分布状况,此结果对薄壁闭合结构多闭室的隔板应力分布问题具有共性,为隔板设计提供... 本文对薄壁双闭室结构隔板上的应力分布情况进行了研究。首先对结构型式进行简化,建立有限元模型,然后用ANSYS软件进行计算,揭示了多闭室结构隔板的应力分布状况,此结果对薄壁闭合结构多闭室的隔板应力分布问题具有共性,为隔板设计提供了借鉴。 展开更多
关键词 薄壁闭合结构 扭转 有限元 应力分布
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The correlation between white matter hyperintensity and balance disorder and fall risk:An observational, prospective cohort study
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作者 Dong-Chao Shen Shuo-Lin Wu +3 位作者 Yu-Zhi Shi Shuo Wang Yu-Mei Zhang Chun-Xue Wang 《慢性疾病与转化医学:英文版》 2016年第3期共8页
Plasticity of motor function and surgical outcomes in patients with cerebral arteriovenous malformation involving primary motor area:insight from fMRI and DTI
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作者 Lijun Wang Fuxin Lin +4 位作者 Jun Wu Yuming Jiao Yong Cao Yuanli Zhao Shuo Wang 《中华神经外科杂志(英文)》 2016年第2期共9页
Electromagnetic transitions in multiple chiral doublet bands
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作者 贾慧 亓斌 +2 位作者 王守宇 王硕 刘晨 《中国物理C:英文版》 SCIE CAS CSCD 2016年第12期91-98,共8页
Multiple chiral doublet bands(M_χD) in the 80,130 and 190 mass regions are studied by the model ofγ=90° triaxial rotor coupled with identical symmetric proton-neutron configurations.By selecting a suitable basi... Multiple chiral doublet bands(M_χD) in the 80,130 and 190 mass regions are studied by the model ofγ=90° triaxial rotor coupled with identical symmetric proton-neutron configurations.By selecting a suitable basis,the calculated wave functions are explicitly exhibited to be symmetric under the operator A,which is defined as rotation by 90° about the 3-axis with the exchange of valance proton and neutron.We found that both M1 and E2 transitions are allowed between levels with different values of A,while they are forbidden between levels with same values of A.Such a selection rule holds true for M_χD in different mass regions. 展开更多
Does novel oral anticoagulant improve anticoagulation for non-valvular atrial fibrillation associated stroke: An inpatient registration study in Shanghai
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作者 Feng-Di Liu Rong Zhao +4 位作者 Xue-Mei Wang Shuo Wang Xiao-Lei Shen Xiao-Xiao Tao Bo Zheng 《慢性疾病与转化医学:英文版》 2015年第4期共7页
Involvement of the visual pathway is not a risk factor of visual field deficits in patients with occipital arteriovenous malformations:an fMRI study
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作者 Xianzeng Tong Jun Wu +4 位作者 Fuxin Lin Yong Cao Yuanli Zhao Zhen Jin Shuo Wang 《中华神经外科杂志(英文)》 2015年第1期共10页
抗金葡菌深海真菌的分离鉴定及抑菌谱研究 被引量:5
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作者 王硕 孟庆丽 +3 位作者 武天娇 赵胜楠 权春善 金黎明 《生物技术》 CAS CSCD 北大核心 2015年第2期169-172,共4页
[目的]从深海淤泥样品中分离筛选具有抗金葡菌特性的真菌菌株,对其进行鉴定,并研究其抑菌谱。[方法]采用稀释涂布平板法分离真菌菌株,对峙培养法初筛,琼脂扩散法复筛,将抑菌效果最好的菌株进行形态鉴定、镜检、26S r DNA鉴定,并研究其... [目的]从深海淤泥样品中分离筛选具有抗金葡菌特性的真菌菌株,对其进行鉴定,并研究其抑菌谱。[方法]采用稀释涂布平板法分离真菌菌株,对峙培养法初筛,琼脂扩散法复筛,将抑菌效果最好的菌株进行形态鉴定、镜检、26S r DNA鉴定,并研究其对产黄青霉、尖孢镰刀菌、黄瓜菌核、木霉、盘单毛孢、平头刺盘孢霉6种真菌和大肠埃希氏菌、单增李斯特菌、副溶血性弧菌、鼠伤寒沙门氏菌4种细菌的抑制作用。[结果]得到1株抑制金葡菌效果最佳的菌株,编号1B12,其抑菌圈直径为35.31 mm,鉴定结果为外瓶霉属(Exophiala),其对上述6种真菌和4种细菌都有一定的抑制作用。[结论]1B12是一株具有广谱抗菌性的海洋真菌。 展开更多
关键词 深海真菌 金黄色葡萄球菌 分离 筛选 26S rDNA鉴定 抑菌谱
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