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一例重症传染性单核细胞增多症合并凝血功能障碍及腹泻患儿的护理 被引量:1
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作者 刘小艳 朱彩金 +1 位作者 宋宁玲 林银璇 《中国实用护理杂志》 2015年第z2期共1页
传染性单核细胞增多症是一种由EB病毒引起的以侵犯淋巴系统为主的急性感染性疾病,临床上多表现为不规则发热、咽痛、淋巴结肿大、肝脾肿大、皮疹、眼睑浮肿、周围血液单核细胞显著增多及头痛、谵妄等神经系统症状;重者可危及生命[1]... 传染性单核细胞增多症是一种由EB病毒引起的以侵犯淋巴系统为主的急性感染性疾病,临床上多表现为不规则发热、咽痛、淋巴结肿大、肝脾肿大、皮疹、眼睑浮肿、周围血液单核细胞显著增多及头痛、谵妄等神经系统症状;重者可危及生命[1]。我科2014年12月收治了1例传染性单核细胞增多症合并合并凝血功能障碍及腹泻的患儿,经积极对症支持治疗及护理,13 d后痊愈出院,现报道如下。 展开更多
螺旋CT肺动脉造影联合临床预测评分对肺动脉栓塞的诊断价值探讨 预览 被引量:2
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作者 王卫东 《临床研究》 2016年第9期171-172,共2页
目的:探讨多层(16层)螺旋CT肺动脉造影(CTPA)联合临床预测评分(Wells评分和修正的Geneva评分)对可疑肺血栓栓塞的预测价值,评价它们对可疑PTE患者的诊断及排除诊断意义。方法收集并分析126例疑似肺栓塞(PTE)患者的临床资料。... 目的:探讨多层(16层)螺旋CT肺动脉造影(CTPA)联合临床预测评分(Wells评分和修正的Geneva评分)对可疑肺血栓栓塞的预测价值,评价它们对可疑PTE患者的诊断及排除诊断意义。方法收集并分析126例疑似肺栓塞(PTE)患者的临床资料。选取76例确诊PTE患者作为诊断组,50例入院后经检查排除PTE的患者作为对照组,对每位可疑(PTE)患者进行临床症状评分(Wells评分和修正Geneva评分)及螺旋CT肺动脉造影检查(CTPA)。结果126例疑诊PTE患者中经CTPA检查确诊76例,排出50例。确诊率为60%(76/126);阳性预测值为88%,特异性92%;临床预测评分高度达到Wells评分>7.5分、Geneva评分>9分时对诊断PTE可能阳性预测值较高;阳性预测值为79%,特异性为63.8%。临床预测评分与CTPA联合后阳性预测值为95%,特异性达98%。结论1.16层螺旋CT肺血管造影是一种简便、无创伤的检查技术,对肺栓塞的诊断敏感性高。临床预测评分值较高时可能敏感性较高,特异性较差。2.三者联合均比单项检查的敏感性及特异性高,且差异均具有统计学意义(P<0.05);对确诊PTE有意义,且三者联合均为阴性时,对肺栓塞具有重要的排除价值。 展开更多
关键词 螺旋CT肺动脉造影 临床预测评分 肺动脉栓塞
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风湿性二尖瓣病变左心房内径与心房颤动触发点相关性研究 被引量:2
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作者 赵健 程兆云 +2 位作者 权晓强 乔刚 李建强 《中国循环杂志》 CSCD 北大核心 2016年第z1期共1页
目的:研究左心房内径与房颤的关系,探讨预测窦性心律二尖瓣病变患者发生房颤的左房内径的临界点。
基层医疗机构中宽QRS波心动过速的特点分析
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作者 刘霞 冯建刚 +2 位作者 裘向军 王金康 吕璧人 《中国循环杂志》 CSCD 北大核心 2016年第z1期共1页
目的:统计在远程心电诊断中心就诊的患者中,宽QRS波心动过速的发生率,并分析基层医疗机构中宽QRS波心动过速的特点。
2017年HRS/EHRA/ECAS/APHRS/SOLAECE心房颤动导管消融和外科消融专家共识解读
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作者 李梦梦 马长生 《中国循环杂志》 CSCD 北大核心 2017年第S2期7-10,共4页
心房颤动(房颤)是临床最常见的心律失常之一,全球房颤总人口已达到3300万以上 [1].历经20余年的探索与发展,房颤导管消融和外科消融技术得以在世界范围内推广应用,成为房颤主要的治疗方式之一.2017年5月在第38届美国心律学会(HRS)年会上... 心房颤动(房颤)是临床最常见的心律失常之一,全球房颤总人口已达到3300万以上 [1].历经20余年的探索与发展,房颤导管消融和外科消融技术得以在世界范围内推广应用,成为房颤主要的治疗方式之一.2017年5月在第38届美国心律学会(HRS)年会上,HRS联合欧洲心律协会(EHRA)、欧洲心律失常学会(ECAS)、亚太心脏节律协会(APHRS)及拉美心脏起搏与电生理协会(SOLAECE)共同颁布了2017版房颤导管和外科消融专家共识》(以下简称'共识').该共识以2012年版专家共识为基础,汇总了近年来的重要循证医学证据,就房颤导管和外科消融的机制、适应证、技术策略及围术期管理等方面进行了全面而深入的阐述,并对该领域的未来发展进行了展望,对临床工作具有重要指导意义.本文就新版共识中重点更新内容进行总结. 展开更多
关键词 指南 心房颤动 导管消融
骨髓间充质干细胞与软骨细胞共培养研究进展 被引量:5
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作者 崔小明(综述) 吴佳奇(审校) 《中国综合临床》 2015年第4期共3页
各种病因所致关节软骨细胞破坏、损伤临床多见,由于关节软骨细胞是增殖能力极弱的终末分化细胞,靠细胞自身增殖修复关节软骨面十分困难。国内外学者对软骨细胞组织工程进行了大量的实验研究,例如自体软骨细胞体外增殖,诱导干细胞向... 各种病因所致关节软骨细胞破坏、损伤临床多见,由于关节软骨细胞是增殖能力极弱的终末分化细胞,靠细胞自身增殖修复关节软骨面十分困难。国内外学者对软骨细胞组织工程进行了大量的实验研究,例如自体软骨细胞体外增殖,诱导干细胞向软骨细胞方向分化[1],体外培养软骨细胞修复关节软骨损伤,自体软骨移植修复关节软骨缺损[2]等,取得了很好的实验效果,但是也面临一些实际问题,如自体软骨细胞获取数量有限,体外软骨细胞去分化现象、老化、致瘤性[3];诱导干细胞向软骨细胞方向分化时,需大量使用生长因子,成本高,有可能引起机体不良反应;体外培养的软骨细胞难以形成成熟软骨细胞等。近年来,一些学者采用骨髓间充质干细胞( bone marrow mesenchymal stem cells BMSCs)和软骨细胞共培养的实验研究,显示了较突出的优势,如实验中尽量避免生长因子的使用,自体软骨细胞量消耗少,培养的软骨细胞分化成熟,增殖能力强等。现将BMSCs 与软骨细胞共培养的实验研究作一综述。 展开更多
关键词 骨髓间充质干细胞 软骨细胞 微环境 三维培养技术
被动血凝抑制试验检测乙型肝炎核心抗体 预览
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作者 郭恒昌 周景筠 +4 位作者 胡宗汉 宋珍珠 顾珮雯 蒋小平 赵曼英 《中华传染病杂志》 CAS 1986年第1期13-16,共4页
乙型肝炎核心抗体(HBcAb)的检测方法有:微量补体结合试验[1]、免疫粘连血凝试验(IAHA)[2,3]、对流免疫电泳[4]、固相放射免疫[5]、酶联免疫吸附试验[6]等,目前国内以后者应用最广.但其不足处为:实验全程影响因素甚多,如载体差异、酶标... 乙型肝炎核心抗体(HBcAb)的检测方法有:微量补体结合试验[1]、免疫粘连血凝试验(IAHA)[2,3]、对流免疫电泳[4]、固相放射免疫[5]、酶联免疫吸附试验[6]等,目前国内以后者应用最广.但其不足处为:实验全程影响因素甚多,如载体差异、酶标记物的降解、酶触反应的动力学各异、底物的自身氧化等,而且要耗用较多的HBcAg及接触有致癌作用的底物. 展开更多
关键词 血凝抑制 试验检测 乙型 肝炎核心抗体 微量补体结合试验 酶联免疫吸附试验 固相放射免疫 对流免疫电泳 自身氧化 致癌作用 影响因素 血凝试验 酶标记物 检测方法 底物 动力学 粘连 载体 应用 实验
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流行性乙型脑炎并发成人呼吸窘迫综合征(附3例报告) 预览
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作者 徐克沂 蔡皓东 《中华传染病杂志》 CAS 1987年第2期111-111,共1页
近年来我院观察到流行性乙型脑炎(乙脑)并发成人呼吸窘迫综合征(ARD8)3例,现报告如下. [例1]男20岁.因发热、头痛5天,嗜睡2天,诊为乙脑,于1982年8月14日入院.入院时T38.9℃.P 80,R 16,BP 120/70,神志清楚,呼吸循环尚好,脑膜刺激征阳性... 近年来我院观察到流行性乙型脑炎(乙脑)并发成人呼吸窘迫综合征(ARD8)3例,现报告如下. [例1]男20岁.因发热、头痛5天,嗜睡2天,诊为乙脑,于1982年8月14日入院.入院时T38.9℃.P 80,R 16,BP 120/70,神志清楚,呼吸循环尚好,脑膜刺激征阳性,病理反射存在.入院第3天出现紫绀,呼吸困难,肺部听诊出现干鸣音及少量中小水泡音,胸部X片示肺纹理增粗,模糊,提示早期肺水肿.血气分析:在吸氧情况下PaO263.8mmHg,PaCO231.2mmHg,吸纯氧30min后Pa02 21OmmHg,A-aDO2 49.5lmmHg,Qs/Qt26.3%,诊为ARDS,给予地塞米松60 mg/d,东莨菪碱,氨茶硷及利尿强心剂,并通过人工呼吸器进行间歇正压呼吸.第2天拍胸片肺水肿消失,缺氧改善.第1O天停用呼吸器,住院28天痊愈出院. 展开更多
关键词 流行性乙型脑炎 成人呼吸窘迫 人工呼吸器 肺水肿 现报告如下 脑膜刺激征 正压呼吸 乙脑 血气分析 呼吸循环 呼吸困难 肺部听诊 东莨菪碱 地塞米松 病理反射 强心剂 肺纹理 氨茶硷 住院 阳性
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血液灌流治疗严重药物或毒物急性中毒 预览 被引量:1
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作者 林康 洪锡祥 +2 位作者 姜国琛 朱美镕 谈佩敏 《中华器官移植杂志》 CAS 1985年第1期8-9,共2页
关键词 血液灌流治疗 药物 毒物 急性中毒
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肺吸虫囊蚴不同方法检出的比较 预览
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作者 李友松 《中国公共卫生学报》 1982年第1期31-33,共3页
众多资料表明,我国之肺吸虫病不但发现早、虫种多、分布广泛,是农村、林区的常见病、多发病,而且由于临床表现复杂,易造成错诊误治,因此,本病的防治研究包括对肺吸虫囊蚴的检查方法,日益
关键词 吸虫 囊蚴 肺吸虫病 福建华溪蟹 沉渣镜检法 消化法 蟹体 流行病学调查 压片法 陈心陶
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Core promoter: A critical region where the hepatitis B virus makes decisions 被引量:2
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作者 Jorge Quarleri 《世界胃肠病学杂志:英文版(电子版)》 SCIE CAS 2014年第2期425-435,共11页
The core promoter(CP)of the viral genome plays an important role for hepatitis B virus(HBV)replication as it directs initiation of transcription for the synthesis of both the precore and pregenomic(pg)RNAs.The CP cons... The core promoter(CP)of the viral genome plays an important role for hepatitis B virus(HBV)replication as it directs initiation of transcription for the synthesis of both the precore and pregenomic(pg)RNAs.The CP consists of the upper regulatory region and the basal core promoter(BCP).The CP overlaps with the 3’-end of the X open reading frames and the 5’-end of the precore region,and contains cis-acting elements that can independently direct transcription of the precore mRNA and pgRNA.Its transcription regulation is under strict control of viral and cellular factors.Even though this regulatory region exhibits high sequence conservation,when variations appear,they may contribute to the persistence of HBV within the host,leading to chronic infection and cirrhosis,and eventually,hepatocellular carcinoma.Among CP sequence variations,those occurring at BCP may dysregulate viral gene expression with emphasis in the hepatitis B e antigen,and contribute to disease progression.In this review these molecular aspects and pathologic topics of core promoter are deeply evaluated. 展开更多
关键词 Hepatitis B virus Core PROMOTER VARIANTS BASAL COR
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####Editorial Board
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《世界胃肠病学杂志:英文版(电子版)》 SCIE CAS 2014年第45期16780-16788,共6页
【正】2014-2017 The World Journal of Gastroenterology Editorial Board consists of 1362 members,representing a team of worldwide experts in gastroenterology and hepatology.They are from 67 countries,including Algeria(2... 【正】2014-2017 The World Journal of Gastroenterology Editorial Board consists of 1362 members,representing a team of worldwide experts in gastroenterology and hepatology.They are from 67 countries,including Algeria(2),Argentina(7),Australia(31),Austria(9),Belgium(11),Brazil(20),Brunei Darussalam(1),Bulgaria(2),Cambodia(1),Canada 展开更多
关键词 representing AUSTRALIA Brazil HEPATOLOGY CANADA ME
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Inflammatory bowel disease: A descriptive study of 716 local Chilean patients
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作者 Daniela Simian Daniela Fluxá +7 位作者 Lilian Flores Jaime Lubascher Patricio Ibánez Carolina Figueroa Udo Kronberg Raúl Acuna Mauricio Moreno Rodrigo Quera 《世界胃肠病学杂志:英文版》 SCIE CAS 2016年第22期5267-5275,共9页
AIM: To demographically and clinically characterize inflammatory bowel disease(IBD) from the local registry and update data previously published by our group.METHODS: A descriptive study of a cohort based on a registr... AIM: To demographically and clinically characterize inflammatory bowel disease(IBD) from the local registry and update data previously published by our group.METHODS: A descriptive study of a cohort based on a registry of patients aged 15 years or older who were diagnosed with IBD and attended the IBD program at Clínica Las Condes in Santiago, Chile. The registry was created in April 2012 and includes patients registered up to October 2015. The information was anonymously downloaded in a monthly report, and the information on patients with more than one visit was updated. The registry includes demographic, clinical and disease characteristics, including the Montreal Classification, medical treatment, surgeries and hospitalizations for crisis. Data regarding infection with Clostridium difficile(C. difficile) were incorporated in the registry in 2014. Data for patients who received consultations as second opinions and continued treatment at this institution were also analyzed. RESULTS: The study included 716 patients with IBD: 508 patients(71%) were diagnosed with ulcerative colitis(UC), 196 patients(27%) were diagnosed with Crohn’s disease(CD) and 12 patients(2%) were diagnosed with unclassifiable IBD. The UC/CD ratio was 2.6/1. The median age was 36 years(range 16-88), and 58% of the patients were female, with a median age at diagnosis of 29 years(range 5-76). In the past 15 years, a sustained increase in the number of patients diagnosed with IBD was observed, where 87% of the patients were diagnosed between the years 2001 and 2015. In the cohort examined in the present study, extensive colitis(50%) and colonic involvement(44%) predominated in the patients with UC and CD, respectively. In CD patients, nonstricturing/non-penetrating behavior was more frequent(80%), and perianal disease was observed in 28% of the patients. There were significant differences in treatment between UC and CD, with a higher use of corticosteroids, and immunosuppressive and biological therapies was observed in the patients with CD(P < 展开更多
关键词 Inflammatory bowel DISEASE Crohn’s DISEASE ULCERATIVE COLITIS South AMERICA LATIN AMERICA Chile EPID
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Diabetes mellitus may affect the long-term survival of hepatitis B virus-related hepatocellular carcinoma patients after liver transplantation
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作者 Qing Zhang Yong-Lin Deng +9 位作者 Chang Liu Li-Hong Huang Lei Shang Xin-Guo Chen Le-Tian Wang Jin-Zan Du Ying Wang Pei-Xiao Wang Hui Zhang Zhong-Yang Shen 《世界胃肠病学杂志:英文版》 SCIE CAS 2016年第43期9571-9585,共15页
AIM to determine whether diabetes mellitus(DM) affects prognosis/recurrence after liver transplantation(Lt) for hepatitis B virus(HBV)-related hepatocellular carcinoma(HCC). METHODS A retrospective study was conducted... AIM to determine whether diabetes mellitus(DM) affects prognosis/recurrence after liver transplantation(Lt) for hepatitis B virus(HBV)-related hepatocellular carcinoma(HCC). METHODS A retrospective study was conducted between January 2000 and August 2013 on 1631 patients with HBV-related HCC who underwent Lt with antiviral prophylaxis. Patient data were obtained from the China Liver transplant Registry(https://www.cltr.org/). to compare the outcomes and tumor recurrence in the HBV-related HCC patients with or without DM, statistical analyses were conducted using χ2 tests, Mann-Whitney tests, the Kaplan-Meier method, log-rank tests and multivariate step-wise Cox regression analysis. RESULTS Univariate analysis of 1631 patients who underwent Lt found overall 1-, 3- and 5-year survival rates of 79%, 73% and 71% respectively in the DM patients, and 84%, 78% and 76% in the non-DM patients respectively. Overall survival rate differences after Lt between the two groups were significant(P = 0.041), but recurrence-free survival rates were not(P = 0.096). By stratified analysis, the overall survival rates in DM patients for age > 50 years(P = 0.002), the presence of vascular invasion(P = 0.096), tumors ≤ 3 cm(P = 0.047), two to three tumor nodules(P = 0.007), Child-Pugh grade B(P = 0.018), and preLt alanine aminotransferase levels between 40 and 80 IU/L(P = 0.017) were significantly lower than in non-DM patients. Additionally, serum α-fetoprotein level > 2000 ng/m L(P = 0.052) was associated with a significant survival difference trend between DM and non-DM patients. Multivariate analysis showed that the presence of DM(P < 0.001, HR = 1.591; 95%CI: 1.239-2.041) was an independent predictor associated with poor survival after Lt. CONCLUSION HBV-related HCC patients with DM have decreased long-term overall survival and poor Lt outcomes. Prevention strategies for HCC patients with DM are recommended. 展开更多
关键词 糖尿病 mellitus Hepatocellular 肝炎 B 病毒 肝移植 幸存
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Gastrointestinal neuromuscular apparatus: An underestimated target of gut microbiota 被引量:1
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作者 Michele Pier Luca Guarino Michele Cicala +1 位作者 Lorenza Putignani Carola Severi 《世界胃肠病学杂志:英文版》 SCIE CAS 2016年第45期9871-9879,
Over the last few years, the importance of the resident intestinal microbiota in the pathogenesis of several gastrointestinal diseases has been largely investigated. Growing evidence suggest that microbiota can influe... Over the last few years, the importance of the resident intestinal microbiota in the pathogenesis of several gastrointestinal diseases has been largely investigated. Growing evidence suggest that microbiota can influence gastrointestinal motility. The current working hypothesis is that dysbiosis-driven mucosal alterations induce the production of several inflammatory/immune mediators which affect gut neuro-muscular functions. Besides these indirect mucosal-mediated effects, the present review highlights that recent evidence suggests that microbiota can directly affect enteric nerves and smooth muscle cells functions through its metabolic products or bacterial molecular components translocated from the intestinal lumen. Tolllike receptors, the bacterial recognition receptors, are expressed both on enteric nerves and smooth muscle and are emerging as potential mediators between microbiota and the enteric neuromuscular apparatus. Furthermore, the ongoing studies on probiotics support the hypothesis that the neuromuscular apparatus may represent a target of intervention, thus opening new physiopathological and therapeutic scenarios. 展开更多
关键词 MICROBIOTA 胃肠的活动性 光滑的肌肉 伤寒神经系统 PROBIOTICS 急躁的肠症候群
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Genotype specific peripheral lipid profile changes with hepatitis C therapy
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作者 Mark R Pedersen Amit Patel +2 位作者 David Backstedt Myunghan Choi Anil B Seetharam 《世界胃肠病学杂志:英文版》 SCIE CAS 2016年第46期10226-10231,
AIM To evaluate magnitude/direction of changes in peripheral lipid profiles in patients undergoing direct acting therapy for hepatitis C by genotype.METHODS Mono-infected patients with hepatitis C were treated with gu... AIM To evaluate magnitude/direction of changes in peripheral lipid profiles in patients undergoing direct acting therapy for hepatitis C by genotype.METHODS Mono-infected patients with hepatitis C were treated with guideline-based DAAs at a university-based liver clinic. Patient characteristics and laboratory values were collected before and after the treatment period. Baseline demographics included age, ethnicity, hypertension, diabetes, hyperlipidemia, treatment regimen, and fibrosis stage. Total cholesterol(TCHOL), high density lipoprotein(HDL), low density lipoprotein(LDL), triglycerides(TG), and liver function tests were measured prior to treatment and ETR. Changes in lipid and liver function were evaluated by subgroups with respect to genotype. Mean differences were calculated for each lipid profile and liver function component(direction/magnitude). The mean differences in lipid profiles were then compared between genotypes for differences in direction/magnitude. Lipid profile and liver function changes were evaluated with Levene’s test and student’s t test. Mean differences in lipid profiles were compared between genotypes using ANOVA, post hoc analysis via the Bonferroni correction or Dunnett T3.RESULTS Three hundred and seventy five patients enrolled with 321(85.6%) achieving sustained-viral response at 12 wk. 72.3% were genotype 1(GT1), 18.1% genotype 2(GT2), 9.7% genotype 3(GT3). Baseline demographics were similar. Significant change in lipid profiles were seen with GT1 and GT3(ΔGT1, p and ΔGT3, p), with TCHOL increasing(+5.3, P = 0.005 and +16.1, P < 0.001), HDL increasing(+12.5, P < 0.001 and +7.9, P = 0.038), LDL increasing(+7.4, P = 0.058 and +12.5, P < 0.001), and TG decreasing(-5.9, P = 0.044 and-9.80 P = 0.067). Among genotypes(ΔGT1 v. ΔGT2 v. ΔGT3, ANOVA), significant mean differences were seen with TCHOL(+5.3 v. +0.1 v. +16.1, P = 0.017) and HDL(+12.3 v. +2 v. +7.9, P = 0.040). Post-hoc, GT3 was associated with a greater increase in TCHOL than GT1 and GT2(P = 0.028 and P = 0.019).CONC 展开更多
关键词 丙肝遗传型 类脂化合物 新陈代谢的症候群
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Effects of Hemp seed soft capsule on colonic ion transport in rats
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作者 Xiao-Fang Lu Meng-Di Jia +1 位作者 Sheng-Sheng Zhang Lu-Qing Zhao 《世界胃肠病学杂志:英文版》 SCIE CAS 2017年第42期7563-7571,共9页
AIM To investigate the effect of Hemp seed soft capsule(HSCC) on colonic ion transport and its related mechanisms in constipation rats.METHODS Sprague-Dawley male rats were randomly divided into three groups: normal... AIM To investigate the effect of Hemp seed soft capsule(HSCC) on colonic ion transport and its related mechanisms in constipation rats.METHODS Sprague-Dawley male rats were randomly divided into three groups: normal group, constipation group and HSSC group. Rats in the constipation and HSSC groups were administrated loperamide 3 mg/kg per day orally for 12 d to induce the constipation model. Then, the HSSC group was given HSSC 0.126 g/kg per day by gavage for 7 d. The normal and constipation groups were treated with distilled water. After the treatment, the fecal wet weight and water content were measured. The basal short-circuit current(Isc) and resistance were measured by an Ussing Chamber. Besides the in vivo drug delivery experiment above, an in vitro drug application experiment was also conducted. The accumulative concentrations of HSSC(0.1 mg/m L, 0.5 mg/m L, 1.0 mg/m L, 2.5 mg/m L, 5.0 mg/m L, 10.0 mg/m L and 25.0 mg/m L) were added to the normal isolatedcolonic mucosa and the Isc was recorded. Further, after the application of either ion(Cl-or HCO3-) substitution, ion channel-related inhibitor(N-phenylanthranilic acid, glybenclamide, 4,4-diisothiocyano-2,2-stilbenedisulfonic acid or bumetanide) or neural pathway inhibitor [tetrodotoxin(TTX), atropine, or hexamethonium], the Isc induced by HSSC was also measured. RESULTS In the constipation group, the fecal wet weight and the water content were decreased in comparison with the normal group(P < 0.01). After the treatment with HSSC, the fecal wet weight and the water content in the HSSC group were increased, compared with the constipation group(P < 0.01). In the constipation group, the basal Isc was decreased and resistance was increased, in comparison with the normal group(P < 0.01). After the treatment with HSSC, the basal Isc was increased(P < 0.05) and resistance was decreased(P < 0.01) in the HSSC group compared with the constipation group. In the in vitro experiment, beginning with the concentration of 1.0 mg 展开更多
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Analysis of haplotype and linkage disequilibrium of PPARγ gene rs12490265,rs1797912,and rs1175543 in patients with metabolic syndrome in Kazakhs of Xinjiang
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作者 张眉 《中国医学文摘:内科学分册(英文版)》 2016年第2期3-4,共2页
<正>Objective To investigate the effect of haplotype and linkage disequilibrium of PPARγgene rs3856806,rs12490265,rs1797912,and rs1175543 in patients with metabolic syndrome(MS)in Kazakhs of Xinjiang.Methods MA... <正>Objective To investigate the effect of haplotype and linkage disequilibrium of PPARγgene rs3856806,rs12490265,rs1797912,and rs1175543 in patients with metabolic syndrome(MS)in Kazakhs of Xinjiang.Methods MALDI-TOF-MS was used to detect PPAPγgene rs3856806,rs12490265,rs1797912,and rs1175543 genotypes in 489 subjects(including 245 MS and 244 con- 展开更多
关键词 HAPLOTYPE LINKAGE PPAR ALLELE confer protective
变应原皮肤点刺试验380例临床分析
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作者 朱国军 王柳芳 《总装备部医学学报》 2015年第3期151-153,共3页
目的分析过敏性疾病的变应原皮肤点刺试验结果,为过敏性疾病的防治及皮肤点刺试验变应原的选择提供依据。方法 2012年4月~2014年4月我院门诊接诊过敏性疾病380例,采用30种变应原(由东莞劲芳生物医药孵化器有限公司提供),加生理盐水阴性... 目的分析过敏性疾病的变应原皮肤点刺试验结果,为过敏性疾病的防治及皮肤点刺试验变应原的选择提供依据。方法 2012年4月~2014年4月我院门诊接诊过敏性疾病380例,采用30种变应原(由东莞劲芳生物医药孵化器有限公司提供),加生理盐水阴性对照和0.1%盐酸组胺阳性对照分别进行皮肤点刺试验。结果本组中有1种变应原阳性312例,占82.1%。30种变应原中以屋尘螨阳性率最高,占72.8%;其次是粉尘螨占70.2%。吸入组动物毛、葎草、豚草分别为36.5%、34.3%、32.3%。食入组鲤鱼、蟹肉、芒果、羊肉、小虾的阳性率分别为15.7%、13.5%、12.2%、11.2%、10.3%。结论屋尘螨和粉尘螨是本组最常见最重要的变应原。变应原皮肤点刺试验安全、迅速、效果可靠、痛苦小,易被患者接受,值得推广使用。 展开更多
关键词 过敏性疾病 变应原 皮肤点刺试验
安眠药治好了“心绞痛”
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作者 朱迪燕 《家庭用药》 2004年第1期51-51,共1页
一年前,我在当地医院被诊断为“冠心病变异性心绞痛”,依据为有心前区疼痛,活动后加重,近期有频发、加重感,休息后减轻,夜间常感到胸闷、呼吸困难而惊醒,被迫坐起等症状,心电图运动负荷试验阳性。但此后一个月,药物治疗不但无... 一年前,我在当地医院被诊断为“冠心病变异性心绞痛”,依据为有心前区疼痛,活动后加重,近期有频发、加重感,休息后减轻,夜间常感到胸闷、呼吸困难而惊醒,被迫坐起等症状,心电图运动负荷试验阳性。但此后一个月,药物治疗不但无效,反而病 展开更多
关键词 安眠药 心绞痛 治疗 中药
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