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Epidemiology, Clinical and Paraclinical Presentations of Pulmonary Embolism: A Cross-Sectional Study in a Sub-Saharan Africa Setting 预览
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作者 Bertrand Hugo Mbatchou Ngahane Félicité Kamdem +9 位作者 Silvain Raoul Simeni Njonnou Nina Chebou Anastase Dzudie Serge Arnold Ebongue Bruno Tengang Fernando Kemta Lekpa Yacouba Mapoure Njankouo Sidick Mouliom Henri Roger Ngote Henry Luma Namme 《呼吸病期刊(英文)》 2019年第3期89-99,共11页
Background: Venous thromboembolic (VTE) disease burden is increasing worldwide, representing a major cause of cardiovascular death and public health problem. Pulmonary embolism (PE) is the most serious clinical presen... Background: Venous thromboembolic (VTE) disease burden is increasing worldwide, representing a major cause of cardiovascular death and public health problem. Pulmonary embolism (PE) is the most serious clinical presentation of VTE. Epidemiological and clinical data on PE are still lacking in Africa, particularly in Cameroon. This study aimed at determining the clinical features as well as imaging presentation and outcome of pulmonary embolism. Methods: A cross-sectional study was carried out in three hospitals in Douala. We retrospectively reviewed patient records admitted for PE from January 2009 to May 2017. We collected data on epidemiology, clinical presentation, venous Doppler/pulmonary computed tomographic angiography (CTA), and outcome. Results: We included 103 patients (56 males) with PE. Their median age was 52 years. The main risk factors were obesity (49.5%), hypertension (35.0%), long trip (24.3%) and cancer (18.4%). The most frequent clinical presentations were dyspnoea (83.4%), chest pain (78.6%), and cough (40.8%). Additionally, pleural effusion (32.8%), atelectasis (25.7%) and pulmonary hyperlucency (20.0%) were the most frequent findings on chest X-ray. The main abnormalities found in electrocardiogram were sinus tachycardia (63.4%), S1Q3T3 aspect (37.6%) and right axial deviation (28.7%). Moreover, right cavities dilatation (26.0%), pulmonary artery hypertension (35.0%) and pulmonary artery dilatation (21.0%) were the main echocardiographic findings. Low-molecular-weight heparin (LMWH) was the initial anticoagulant in all cases. There were 19 (18.4%) in-hospital deaths, and the mean hospital stay was 8.5 ± 5 days. Conclusion: PE is not rare in our setting. Obesity, long trip and cancer are the main risk factors, while dyspnoea, chest pain and respiratory distress are the main clinical presentation for PE. LMWH remains the therapeutic agent of choice. Lastly, in-hospital mortality is very high. 展开更多
关键词 EPIDEMIOLOGY Africa VENOUS THROMBOEMBOLISM SYMPTOMS
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<i>Taenia solium</i>Cysticercosis in Sub-Saharan Africa: Perspectives for a Better Control 预览
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作者 Beda John Mwang’onde 《传染病进展(英文)》 2019年第2期105-121,共17页
For decades, Taenia solium cysticercosis (TSC) has remained an important constraint for public health and economic well being of the predisposed communities. Despite the fact that the disease is easily preventable, hu... For decades, Taenia solium cysticercosis (TSC) has remained an important constraint for public health and economic well being of the predisposed communities. Despite the fact that the disease is easily preventable, humans remain foci for transmission. They harbour the mature form of the parasite (Taenia solium) which may be curable at this stage and also easily prevented from contaminating pig feeds and environment with eggs of the parasite to break the cycle. Researchers, knowledgeable communities and international organisations such as the World Health Organisation work hard to make the disease a history. Nevertheless, persistence of the disease in endemic regions such as sub Saharan Africa is kept on increasing. While TSC in human may serve as a silent killer as it can go unnoticed for years, the immanent social cultural settings and lifestyles of the communities in endemic areas form the main concern on the epidemiology of the disease. Unless lifestyles change in endemic regions, front line research might rarely find its way into applications in an area of huge societal and economic impact, the TSC epidemiology. Sincerely, transmission of TSC is favoured by poor sanitation and hygiene which is motivated by lifestyle and poverty. What is perhaps missing is the knowledge on “why is the communities involved ease indiscriminately while almost every member of the community in endemic areas knows that indiscriminate defecation may harm their health? What social drivers are behind this motive (bush defecation)? How best can the disease be controlled and monitored? This review recommends for developing and implementing an interdisciplinary OneHealth community-based control mechanism and monitoring (surveillance) programme as standpoints towards eliminating TSC in sub-Saharan Africa and the rest endemic regions. 展开更多
关键词 TAENIA solium CYSTICERCOSIS EPIDEMIOLOGY Sub Saharan AFRICA
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Epidemiological Features of Patients with Craniomaxillofacial Fractures: A Single Centre Study 预览
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作者 Mohamed Khallaf Mohammed S. Shahine 《现代神经外科学进展(英文)》 2019年第2期132-144,共13页
Purpose: It has been shown that cranial injuries associated with facial fractures may cause a great risk of mortality and neurological morbidity, which mainly occurs in young adults. Various studies have been carried ... Purpose: It has been shown that cranial injuries associated with facial fractures may cause a great risk of mortality and neurological morbidity, which mainly occurs in young adults. Various studies have been carried out in various countries to study the epidemiology of the cranio maxillofacial injuries but the studies from Egypt are few. The aim of this study was therefore to assess the prevelance, etiology, type of injury, and site of fractures among patient attending Assiut University Hospitals. Material and Methods: Retrospective hospital study was carried out at Trauma unit, Assiut University Hospitals (Single Tertiary Hospital) between January 2010 and December 2017. Radiographs and hospital data of 1745 patients with craniomaxillofacial trauma were gathered and analyzed. The identified fractures, such as, age, gender, etiology of injury, and anatomical sites of fractures were classified as: frontal/skull base, naso-orbital, maxilla, zygoma, and mandible. According to GCS, patients were classified into 3 grades: mild, moderate and severe. Gathered data was coded and entered into a computer and analyzed using SPSS version 22. Result: Overall prevalence of cranio maxillofacial injuries was 3%. Age ranged from 1 - 90 with mean ± SD 25.75 ± 15.5. The greatest number of the patients had 18 to 40 years old (48.4%) and most of them were male (M/F ratio was 7:1). The most prevalent causes of the trauma in this study were the road traffic accidents (67.7%) and accidental fall (15%), respectively. Firearm injuries accounted for fractures in 86 patients (4.9%). The most common bone fracture among the patients was the mandibular bone (47.7%). 837 patients (48%) required surgical intervention. Conclusions: This retrospective population study demonstrates an insight into the demographics and fracture patterns in craniomaxillofacial trauma patients. The most common etiology of craniomaxillofacial injury was road traffic accidents followed by falls and assaults, suggesting that interventions addressing the prevention of 展开更多
关键词 Cranio MAXILLOFACIAL TRAUMA EPIDEMIOLOGY Assiut
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Epidemiology of Venous Thrombo-Embolic Disease in Yaounde: A Cross-Sectional Study in Sub-Saharan Africa 预览
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作者 Sylvain Raoul Simeni Njonnou Chris Nadège Nganou-Ngnindjo +11 位作者 Ba Hamadou Bonaventure Jemea Ahmadou Musa Jingi Jerome Boombhi Aimée Tiodoung Timnou Marie-Josiane Ntsama Essomba Lydienne Alida Tonye Aicha Mefire Yap Murielle Florence Helles Lema Liliane Mfeukeu-Kuate Sylvie Ndongo Amougou Samuel Kingue 《心血管病(英文)》 2019年第5期360-369,共10页
Background: Venous thromboembolic disease (VTE) is one of the main causes of cardiovascular death and a public health problem worldwide. It is?one of the most complications in admitted patients, particularly inlow-inc... Background: Venous thromboembolic disease (VTE) is one of the main causes of cardiovascular death and a public health problem worldwide. It is?one of the most complications in admitted patients, particularly inlow-income settings. The epidemiological data on VTE are still lacking. Methods: We carried out a cross-sectional study in three hospitals in Yaoundé. We retrospectively reviewed records of patients admitted for VTE from January 2013 to December 2017. We collected data on socio-demography, clinical presentation, venous Doppler/pulmonary CT scan, and outcome. Results: We included 93 patients (43 males) with VTE. Their mean age was 53.3 ± 16.6 years. There were 46 (49.5%) cases of Deep Vein Thrombosis (DVT), 36 (38.7%) cases of Pulmonary Embolism (PE), and 11 (11.8%) cases of PE associated with DVT. The main risk factors were obesity/overweight (58.1%), immobility (43%), HIV infection (22.6%), prior admission (22.6%), and long trip (19.4%). The most frequent clinical presentation for PE was dyspnea (100%), tachypnea (87.2%), and chest pain (70.2%). For DVT, limb pain (93%), calf stiffness (86%), limb volume > 3 cm (82.4%) were the most common presentation. There were 9 (9.7%) in-hospital deaths. Mean hospital stay was 20.7 ± 30.8 days. Conclusion:VTE is underdiagnosed in our setting. Obesity and immobility were the main risk factors. Dyspnea and tachypnea were the main clinical presentation for PE whereas limb pain and calf stiffness were the main symptoms for DVT. In-hospital mortality is still high. 展开更多
关键词 VENOUS THROMBOEMBOLIC DISEASE EPIDEMIOLOGY Yaounde Sub-Saharan Africa
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Epidemiological Study and Optimal Control for Lumpy Skin Disease (LSD) in Ethiopia 预览
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作者 Okey Oseloka Onyejekwe Abebe Alemu +1 位作者 Biruk Ambachew Ayalnesh Tigabie 《传染病进展(英文)》 2019年第1期8-24,共17页
Lumpy skin disease (LSD) is an infectious, fatal skin disease of cattle caused by a virus of the family Poxviridae (genus Capripox). In addition, severely affected animals suffer from reduced weight, cessation of milk... Lumpy skin disease (LSD) is an infectious, fatal skin disease of cattle caused by a virus of the family Poxviridae (genus Capripox). In addition, severely affected animals suffer from reduced weight, cessation of milk production and infertility. The aim of this paper is to computationally apply epidemiological (SEIR) and optimal control (OC) techniques to study the transmission and the impact of vaccination on LSD. Based on our numerical experiments, we were able to deduce the overall impact of the optimal strategy adopted for this study on the cattle population for vaccination rates within the range of 0 ≤ v ≤ 0.85. It is shown that the vaccination as a control strategy significantly reduced the effects of LSD on the cattle population if properly managed and that an optimal performance of the control strategy adopted hererin is achieved at an approximate value of v = 0.6. 展开更多
关键词 Lumpy SKIN DISEASE LSD OPTIMAL Control EPIDEMIOLOGY SEIR
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Risk Factors of Renal Failure in HIV Patients at Initiation of ARV Treatment: Retrospective Study of 3118 Patients Followed in Infectious Diseases Department at Lom&#233;University Hospital 预览
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作者 Eyram Yoan Makafui Amekoudi Kossi Akomola Sabi +5 位作者 Badomta Dolaama Komlan Georges Tona fa Noto-Kadou-Kaza Epiphane Kola Bayaki Saka 《肾脏病(英文)》 2019年第3期55-64,共10页
HIV infection is a major cause of chronic kidney disease, associated with high morbidity and mortality in sub-Saharan Africa. The objective of this study is to assess the prevalence and risk factors of renal disease a... HIV infection is a major cause of chronic kidney disease, associated with high morbidity and mortality in sub-Saharan Africa. The objective of this study is to assess the prevalence and risk factors of renal disease at initiation of antiretroviral therapy. This was a descriptive and analytical retrospective study carried out in the infectious and tropical diseases department at Sylvanus Olympio University Hospital. The data have been extracted from the ESOPE software. Kidney disease was defined by a GFR, estimated by MDRD (Modification of Diet in Renal Disease) formula, less than 60 ml/min/1.73 m2. Risk factors associated with kidney disease were assessed using univariate and multivariate analysis. There were 3118 HIV-infected patients included in our study. The median estimated filtration rate was 94.7 ml/min/1.73 m2: 2.9% had an eGFR 2. 1303 had kidney disease (41.8%). Most patients (30.8%) were in the WHO clinical stage 1. The median CD4 count was 165/μL [IQR = 72 - 274/μL];the median hemoglobin level was 10.4 g/dL [IQR = 8.8 - 11.9 g/dL];all patients had thrombocytopenia less than 100.000/mm3;8.5% had leukocytosis greater than 10.000/mm3. Most of patients had HIV1. In the multivariate analysis, age greater than 40 years (p 3 were significantly associated with renal disease. The prevention of kidney disease must go through the identification of its risk factors in the target populations. 展开更多
关键词 HIV Chronic Kidney Disease Epidemiology TOGO
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Epidemiological Pattern of Closed Femoral Shaft Fractures in a Regional Tertiary Hospital in Enugu, Nigeria 预览
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作者 E. C. Iyidobi R. T. Ekwunife +3 位作者 U. M. Enweani C. U. Nwadinigwe I. C. Okwesili H. C. Ekwedigwe 《生物科学与医学(英文)》 2019年第5期180-188,共9页
Background: The femur is the longest and strongest tubular bone in the human body. The femoral shaft is the portion of the bone between 5 cm distal to the lesser trochanter and 6 cm proximal to the most distal point o... Background: The femur is the longest and strongest tubular bone in the human body. The femoral shaft is the portion of the bone between 5 cm distal to the lesser trochanter and 6 cm proximal to the most distal point of the medial femoral condyle. Femoral shaft fractures often result from high energy forces. These fractures occur mostly among young adults. Objective: This was to determine the epidemiological pattern of closed femoral shaft fractures in a regional tertiary hospital in Enugu, Nigeria. Method: The study was a prospective study over a 12 month period (June 2015-May 2016) at National Orthopaedic Hospital, Enugu. Following ethical approval and written informed consent, patients were consecutively recruited. The patients were clinically and radiographically evaluated at presentation. The diagnosis of closed femoral shaft fractures were made from the physical examination finding of absent open wound communicating with the fracture hematoma in the thigh and anteroposterior (AP) and lateral x-rays of the affected thigh confirming the fracture pattern. The data collected included patients’ demographics, the cause of injury, the side of injury and anatomic site of the injury among other parameters. The data were collected using well designed and structured proforma. Results: A total of 52 femoral shaft fractures in 50 patients were included and analyzed using SPSS version 20.0. The age range of the patients is 18 - 85 years with a median age of 39.1 ± 14.9 years. The most commonly affected age group is 21 - 30 years. There was male preponderance with a male to female ratio of 2.3:1. Majority of the fractures (76.9%) resulted from road traffic crashes most commonly following motor vehicular accident (36.5%). Majority of the fractures (92.3%) are unilateral with right side to left side ratio of 1.2:1. Majority of the patients (51.9%) had Winquist Hansen grade III type of fracture. The most common associated injury is fractures of tibia/fibula followed by fracture of the neck of the ipsilateral femur. All the 展开更多
关键词 Epidemiology CLOSED FEMORAL SHAFT Fracture
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Profile of Patients Treated in Outpatient Vestibular Rehabilitation at a Hospital in S&atilde;o Paulo 预览
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作者 Bárbara Vieira Coró Miguel Angelo Hyppolito +1 位作者 Camila Giacomo Carneiro Barros Ana Paula do Rego André 《临床医学国际期刊(英文)》 2019年第1期9-15,共7页
Introduction: Currently it is very common that the search for diagnosis and treatment for curing diseases can cause vertigo or dizziness. Objective: This study sought to characterize the profile of patients seen in th... Introduction: Currently it is very common that the search for diagnosis and treatment for curing diseases can cause vertigo or dizziness. Objective: This study sought to characterize the profile of patients seen in the clinic for vestibular rehabilitation in a tertiary hospital in the last 10 years. Methods: Survey questionnaires of patients with dizziness. Results: The prevalence of treated subjects was female 65.3% (N = 439). The average age was 54.9 years old. Dizziness type roundabout was more prevalent 33.04% (N = 222). Tinnitus occurred in 58.33% of the population. The time of most observed dizziness was less than 5 years 70.68% (N = 475). Neurovegetative symptoms appeared in 63.98% (N = 430) of the population. The bilateral normal hearing was more standard 35.26% (N = 237). The topographic diagnosis of peripheral origin was the most usual 65.47% (N = 440). Conclusion: The peripheral otoneurologic involvement was more prevalent in this population, affecting more women at an average age of 54.9 years old. The most prevalent symptoms were vertigo, nausea, tachycardia, sweating, vomiting and tinnitus, characterizing the peripheral vestibular impairment. The time of dizziness was less than five years. Audiological standard normal curve was predominant and the symptom of tinnitus was the most reported. The most prevalent comorbidity was Hypertension. 展开更多
关键词 DIZZINESS EPIDEMIOLOGY REHABILITATION
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Buruli Ulcer: Epidemiological, Clinical and Biological Profile of Patients in the Centre de Depistage et de Traitement d’Allada (Benin) from 2010 to 2014 预览
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作者 Bérénice Dégboé Christiane Koudoukpo +6 位作者 Mouhaéminath Alimi Ghislain Emmanuel Sopoh Fabrice Akpadjan Roch Christian Johnson Nadège Agbéssi Hugues Adégbidi Félix Atadokpèdé 《化妆品、皮肤病及应用期刊(英文)》 2019年第2期67-82,共16页
Introduction: The objective of our work was to describe the epidemiological, clinical and biological profile of Buruli ulcer in “Centre de Dépistage et de traitement de l’ulcère de Buruli” (CDTUB) in Alla... Introduction: The objective of our work was to describe the epidemiological, clinical and biological profile of Buruli ulcer in “Centre de Dépistage et de traitement de l’ulcère de Buruli” (CDTUB) in Allada. Methods: A descriptive and retrospective study focused on new cases of Buruli ulcer received in the CDTUB of Allada from 2010 to 2014. The diagnosis of Buruli ulcer was based on epidemiological, clinical and biological arguments. Results: Over 5 years, 274 new cases of Buruli ulcer have been diagnosed. The average age of the patients was 12 years and the sex ratio was 0.8. The average time to first consultation was 45 days. Clinically, 61% had a joint functional limitation. Lesions were ulcerated in 69% of cases, category I (26%), category II (53%), category III (21%) and were present on the lower limbs in 57% of cases. Microscopy was positive in 65.7% of cases and PCR in 78.1% of cases. Microscopy supplemented by PCR confirmed the diagnosis in 81% of cases. Conclusion: The epidemiological, clinical and biological profile of Buruli ulcer in Allada was characterized by a predominant disease in children, a predominance of ulcerated forms and a decisive contribution of PCR to the diagnosis. 展开更多
关键词 Buruli Ulcer Epidemiology CLINICAL PROFILE BIOLOGICAL CONFIRMATION BENIN
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Epidemiological and Clinical Profile of Breast Cancer at Bamako Radiotherapy Center 预览
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作者 A. S. Kone A. Diakite +4 位作者 I. M. Diarra K. Diabate M. A. Camara Y. L. Diallo S. Sidibe 《癌症治疗(英文)》 2019年第9期739-746,共8页
Breast cancer is a major public health problem because of its incidence and mortality. Purpose: To establish the epidemiological and clinical characteristics of breast cancer seen at the radiotherapy center at the Mal... Breast cancer is a major public health problem because of its incidence and mortality. Purpose: To establish the epidemiological and clinical characteristics of breast cancer seen at the radiotherapy center at the Mali Hospital of Bamako. Patients and methods: It was a retrospective, descriptive study of data from patients seen for breast cancer at the Center of Radiotherapy of Mali Hospital between April 2014 and December 2016. The parameters studied were: age, sex, family history of breast cancer, menopausal status, parity, breast tumor location, histological type, histological grade, cancer classification stage. Results: 134 cases of breast cancer were collected, with a frequency of 15%. The sex ratio (H/F) of 0.007. The patient’s mean age was 47 ± 11 years old. The most represented age groups were 33 - 47 years old with 45.5% and 48 - 62 years old with 39%. Three percent (3%) of patients had a family history of breast cancer. Fifty (50%) of the patients were menopausal. The main clinical signs found were : mammary nodules (98%), mastodynia (65%), nodes (67%). Invasive ductal carcinomas were found in 94% of patients, followed by infiltrating lobular carcinomas with 3.7% and metaplastic carcinomas with 1.7%. SBR Grades II and III were mostly found with 37% and 23%. The average tumor size was 87 mm ± 43. Stage III was predominantly represented with 72%, followed by Stage II with 24% and Stages I and IV with 2% each. Conclusion: Breast cancer is common and reaches both before and after 50 years;the diagnosis is usually late;hence it is the importance of raising awareness and screening before the age of 50 and popularizing some complementary tests to better understand the prognosis of this disease and promote more targeted and conservative treatments that will improve survival. 展开更多
关键词 BREAST Cancer EPIDEMIOLOGY CLINIC
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Analogy between the Formulation of Ising-Glauber Model and Si Epidemiological Model 预览
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作者 Cristina Gabriela Aguilar Lara Eduardo Massad +1 位作者 Luis Fernandez Lopez Marcos Amaku 《应用数学与应用物理(英文)》 2019年第5期1052-1066,共15页
From the mathematical point of view, the modeling of epidemics—in other words, the spread of infectious diseases transmitted from individual to individual—is very similar to the modeling of the magnetic systems stud... From the mathematical point of view, the modeling of epidemics—in other words, the spread of infectious diseases transmitted from individual to individual—is very similar to the modeling of the magnetic systems studied by statistical physics. In this work, we use this analogy between mathematical epidemiology and statistical physics to study the classical mathematical model of epidemiology SI (Susceptible-Infected) approached through the Ising-Glauber model, in which individuals would be represented by atoms with spins -1 (susceptible) and 1 (infected). A Monte Carlo computational simulation was also performed for the Ising-Glauber model in a square network, where each network point represents an individual and the down and up spins represent susceptible and infected individuals. 展开更多
关键词 Ising-Glauber Model EPIDEMIOLOGY Computer Simulation
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Molecular Epidemiology of High-Risk Human Papilloma Virus Infection in Sexually Active Women at Bobo-Dioulasso University Teaching Hospital 预览
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作者 Souleymane Ouattara Der Adolphe Somé +6 位作者 Adama Dembélé Salif Sanfo Théodorat Zohoncon Abdoul-Karim Ouattara Moussa Bambara Blami Dao Jacque Simporé 《妇产科期刊(英文)》 2019年第8期1178-1188,共11页
The objective of this study was to determine the prevalence of HPV-HR genotypes in the population of sexually active women in Bobo-Dioulasso, Burkina Faso. Methods: This study took place at Souro Sanou Teaching Hospit... The objective of this study was to determine the prevalence of HPV-HR genotypes in the population of sexually active women in Bobo-Dioulasso, Burkina Faso. Methods: This study took place at Souro Sanou Teaching Hospital in Bobo-Dioulasso from September to June 2017. A total of 234 women in the gynecological period and also sexually active were enrolled after they gave an individual consent. Swabbing of the endocervical canal was done. From the sample stored at -20°C, the viral DNA was extracted using the “DNA-Sorb-A” kit from SACACE biotechnologies&reg. Amplification of the PCR of the extracted DNA was made, using the “HPV Genotypes 14 Real-TM Quant” V67-100 FRT kit. Data were analyzed with SPSS software version 17.0 and Epi Info 6. Chi-square and Fisher’s tests were used to compare proportions and averages;a link was significant when p 0.05. Results: The mean age was 30.7 ± 7.3 years (median: 30 years);84.5% of them were married, 43.5% had a socio-professional activity and 61% were schooled. A total of 20.6% of women were positive for at least one of the following HPV-HR genotypes: HPV 18, 31, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68. Genotypes the most frequently found were HPV 52 with 11 cases (17.2%) and 66 with 10 cases (15.6%). Conclusion: Our results show a predominance of HPV-HR genotypes not covered by available vaccines. Mapping genotypes are needed to fully understand viral ecology at the national level. But for instance, the nonavalent vaccine, which has a better coverage of the predominant genotypes, is to be promoted. 展开更多
关键词 HPV-HR EPIDEMIOLOGY GENOTYPES Bobo-Dioulasso
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Seroprevalence of Cryptosporidium and risks of cryptosporidiosis in residents of Sothern Egypt: A cross-sectional study
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作者 Ismail Elshahawy Fatma AbouElenien 《亚太热带医药杂志:英文版》 SCIE CAS 2019年第5期232-238,共7页
Objective: To identify the serological epidemiology of Cryptosporidium infections and to follow up on the changes in the infection profile in Southern Egypt in order to establish a suitable scheme for control and prev... Objective: To identify the serological epidemiology of Cryptosporidium infections and to follow up on the changes in the infection profile in Southern Egypt in order to establish a suitable scheme for control and prevention of cryptosporidiosis.Methods: A total of 1 912(960 from human and 952 from animals) stool specimens and sera were screened for Cryptosporidium species using modified Ziehl Neelsen technique and a newly-developed enzyme-linked immunosorbent assay(ELISA).Environmental risk factors and socioeconomic data were surveyed by questionnaire between September 2016 and December 2017.Results: Totally, 20.83% of the human subjects were positive for Cryptosporidium infection tested by ELISA.The seropositivity was positively correlated with age.The prevalence of Cryptosporidium infections in females was significantly higher than in males(P<0.05).The sensitivity and specificity of ELISA for Cryptosporidium were 99.06% and 88.88%, respectively.Furthermore, a high prevalence of Cryptosporidium in domestic animals(42.20%).Conclusions: The study observed that Cryptosporidium infections are common in the study area, with water sanitation, socioeconomic level;eating habits and hygienic status are considered the main risk factors for cryptosporidiosis.Therefore, environmental sanitation and health education will be useful in reducing the prevalence of infection. 展开更多
关键词 CRYPTOSPORIDIUM EPIDEMIOLOGY ELISA test Risk factors Serum EGYPT
Epidemiology and Management of Ectopic Pregnancy in Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Southeast, Nigeria 预览
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作者 Bridget Nkiruka Uche-Nwidagu Vitus Okwuchukwu Obi +4 位作者 Johnbosco Ifunanya Nwafor Assumpta Nnenna Nweke Chinwe Wendy Oliobi Malachy Chizoba Onyema Paschal Chijioke Okoye 《妇产科期刊(英文)》 2019年第8期1202-1211,共10页
Background: Ectopic pregnancy is a common cause of maternal morbidity and mortality in the 1st trimester of pregnancy;without timely diagnosis and intervention, ruptured ectopic pregnancy can become a life threatening... Background: Ectopic pregnancy is a common cause of maternal morbidity and mortality in the 1st trimester of pregnancy;without timely diagnosis and intervention, ruptured ectopic pregnancy can become a life threatening condition. Objective: This study aims to give baseline indices on the incidence, clinical presentation, risk factors and the management of cases of ectopic pregnancy that presented in Alex Ekwueme Federal University Teaching Hospital, Abakaliki over a 5-year period. Materials and Method: This is a 5-year retrospective study of patients who were diagnosed with ectopic pregnancy between January 1st 2012 and December 31st 2016. The statistical analysis was done using SPSS version 22. Result: During the study period, there were 11,932 deliveries while 7725 Gynaecology patients were admitted. Over the same period there were 156 patients diagnosed and managed for ectopic pregnancy, accounting for 1.31% of all deliveries and 2.0% of all Gynaecological admissions. The modal age group was 26 - 30 years 68 (43.6%), 122 (78.2%) were married, while 34 (21.7%) were single. Nulliparous were 41 (26.3%) and primiparous were 33 (21.2%). The commonest presenting complaints were lower abdominal pain and amenorrhea, and the commonest identified risk factor was previous pelvic inflammatory disease. Most of the cases were ruptured prior to presentation and partial salpingectomy was the management in all tubal pregnancy while two cases were unruptured and had salpingostomy and another case was abdominal pregnancy and had exploratory laparotomy only. Out of 156 women that presented with ectopic pregnancy, 8 (5.1%) died before surgery could be done due to late presentation. Fifty-seven women presented in a state of shock and 9 (5.8%) of the cases were complicated with acute renal failure. Conclusion: Ruptured ectopic pregnancy is a major cause of maternal morbidity and early pregnancy loss. Late presentation is a common feature in our environment;hence widespread advocacy on case identification and early presentation is urg 展开更多
关键词 EPIDEMIOLOGY MANAGEMENT ECTOPIC PREGNANCY Abakaliki
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Epidemiological, Clinical and Therapeutic Issues of Epulis at Campus University Teaching Hospital of Lom&#233;: About 33 Cases 预览
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作者 Saliou Adam Hamza Dolè +15 位作者 s Sama Palokina Agoda Haré gué na Bissa Winga Foma Essobozou Plaoudé zina Pegbessou Bathoké ou Amana Essoham Boko Eyawè lohn Kpemissi 《口腔学期刊(英文)》 2019年第7期168-174,共7页
Introduction: The epulis is a hyperplastic tumor-like of the gingival or cheek mucosa that would be due to inflammatory reactions. Its pathogenesis remains incompletely understood. It appears to be common in Africa, b... Introduction: The epulis is a hyperplastic tumor-like of the gingival or cheek mucosa that would be due to inflammatory reactions. Its pathogenesis remains incompletely understood. It appears to be common in Africa, but no study has been conducted in Togo. Our purpose was to describe epidemiological, clinical and therapeutic aspects of the epulis at the Campus University Teaching Hospital in Lomé. Patients and methods: This was a retrospective descriptive study on 33 cases at the Odontostomatology Department, from January 1st, 2014 to December 31st, 2016. Results: The prevalence of epulis was 0.88%. The average age of the patients was 36.92 years old. The most affected age group was 20 - 29 years old (30.30%). The sex ratio was 0.57. Low education and poor socio-economic conditions were found to be predisposing factors. Mucous swelling was the main reason for consultation. A local irritative factor was found in more than half of the cases. The preferred seat was gum (63.63%). Inflammatory epulis was found in 36.36% of cases. Biopsy-excision was performed in 96.96% of patients, with a cure without sequelae in 100%. Conclusion: The epulis is a rare benign affection of the gum. Its favoring factors are mechanical or infectious local irritation, or hormonal factors. His diagnosis is essentially clinical, but requires histological confirmation to distinguish it from other serious tumors. Biopsy-excision is the main treatment. No sequelae are observed in all patients of our series. 展开更多
关键词 EPULIS Epidemiology CLINIC Treatment TOGO
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Neurological Disorders among the Outpatients Living with Human Immuno Deficiency Virus (HIV) Following at the Parakou Hospital in 2014 预览
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作者 Adoukonou Thierry Agbétou Mendinatou +6 位作者 Dassi Gbénou Jolianelle Ahanhanzo Rhonel Kpangon Arsene Kossi Oyéné Agballa Gottfried Dovonou Albert Houinato Dismand 《神经系统科学与医药(英文)》 2019年第3期199-206,共8页
Objective: To study the frequency of neurological disorders associated to HIV infection. Methods: This cross-sectional study was carried out from 16th June to 16th September 2014 and included all 289 HIV-outpatients a... Objective: To study the frequency of neurological disorders associated to HIV infection. Methods: This cross-sectional study was carried out from 16th June to 16th September 2014 and included all 289 HIV-outpatients admitted to the Parakou University hospital. All data were recorded, physical examination was performed and the medical sheet of each patient was assessed. The diagnosis of neurological disorder (central and peripheral) was based on clinical features, past medical history, biological test and CT-scan data after multidisciplinary staff. Epi-data and Epi-Info 6.04C were used to perform analysis. Results: They were 73 (25.3%) male with a mean age of 38.0 years +/&#8722;?10.1 years. The mean duration of disease was 48.5 months +/&#8722;37.1 months. 150 (51.9%) of them were at Stage 3 of the disease. All patients (99.7%) were infected by HIV1, 188 (76.1%) had CD4 cells at the onset of the follow-up less than 350 cells/mm3 and 260 (90.0%) were on ART. Among the 289 patients, 110 had at least one neurological disorder, the frequency of neurological disorders was 38.1%. The main neurological disorders were peripheral neuropathy (34.3%), isolated headache (5.2%), stroke (0.7%), cerebral toxoplasmosis (0.7%) and one case of dementia (0.7%). The main associated factors were the age of patient and exposure on neurotoxic drug, especially ART. Conclusion: The neurological disorders were more frequent among HIV patients with a high frequency of peripheral neuropathy probably due to ART. 展开更多
关键词 NEUROLOGICAL DISORDERS HIV AIDS Peripheral NEUROPATHY Epidemiology
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Epidemiological and Clinical Profile of Cervix Cancer at Bamako Radiotherapy Center 预览
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作者 A. Diakité A. S. Koné +8 位作者 Y. L. Diallo K. Diabaté I. M. Diarra M. Ndiaye M. A. Camara M. M. Traoré A. Traoré F. M. Sidibé S. Sidibé 《妇产科期刊(英文)》 2019年第1期92-97,共6页
Cervical cancer remains a major public health problem in Africa, particularly in Mali. The goal of this work was to investigate the epidemiological and clinical aspects of cervix cancer seen at the radiation therapy c... Cervical cancer remains a major public health problem in Africa, particularly in Mali. The goal of this work was to investigate the epidemiological and clinical aspects of cervix cancer seen at the radiation therapy center. This was a descriptive study on the retrospective collection of data on patients found in the Radiation Therapy Centre of Bamako, for invasive cervical cancer be-tween April 2014 and April 2017. The average age of our population was 52 ± 12.5 years with extremes ranges from 18 to 95 years. The most represented age group was [50 - 65 years] with 44.2%. The predominant histological type was squamous carcinoma (CE) with 94.2%. Bleeding were found in almost all patients, most often associated with foul smelling hydrorrhea;80.3% of our patients were stage III and 12.9% of stage IV according to the IFGO classifi-cation. Cervix cancer remains a major public health problem in Mali. The di-agnosis is often late, therefore, resulting in late care and unfavorable progno-sis. Sensitization, vulgarization of vaccination and systematization of screen-ing could be helpful in the fight against this cancer. 展开更多
关键词 EPIDEMIOLOGY CLINIC CERVIX Cancer
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Pregnancy and Oral Pathology 预览
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作者 Nafiou Idi Mahamane Rhissa Moussa +1 位作者 Souleymane Aichatou Anahi Kaka Yakoura Abba 《妇产科期刊(英文)》 2019年第11期1456-1463,共8页
Introduction: Dental pathologies during pregnancy can compromise the prognosis of pregnancy and that of the mother. We report a first-study of cases of association of pregnancy and oral pathology supported in the Depa... Introduction: Dental pathologies during pregnancy can compromise the prognosis of pregnancy and that of the mother. We report a first-study of cases of association of pregnancy and oral pathology supported in the Department of Odonto-stomatology of the National Hospital of Niamey. Objective: To report epidemiology, treatment and prognosis of dental origin cervicofacial cellulitis associated with pregnancy. Patients and Methods: This is a retrospective and prospective study over 5 years from August 1st, 2013 to July 31, 2018 involving 21 pregnant women in the Odonto-stomatology Department of the National Hospital of Niamey (HNN). Results: During the study period, 585 patients were consulted in the Odonto-stomatology Department for cervicofacial tooth cellulitis of dental origin, 21 of them were pregnant women (3.39%). The average age of the pregnant patients was 29.57 years old, extrems 25 - 29 years old. The average delay before consultation was 28.76 days. Majority patients were rural inhabitants The pathology happened in the third trimester of pregnancy (52.39%), second trimester (33.33%), in first (14.29%). This pathology was observed among disadvantaged socioeconomic class as housewives (85.71%) and uneducated women (61.90%). The lake of oral hygien was the main cause of cellulitis. We noted a history of periodontal disease (52.38%), fever upper 38°C (61.90%), trismus (85.71%,) dysphonia (42.86%), odynophagia (23.81%), dysphagia (42.86%), dyspnea (33.33%), and cervicofacial swelling (100%.) The treatment was medico-surgical. The prognosis depended on the precocious treatment with 76.19% cured. But unfortunately 4 cases died (19.05%), still for birth (52.38%) and 9.52% abortion. Conclusion: Association dental origin cervicofacial c 展开更多
关键词 Cervico-Facial CELLULITIS PREGNANCY EPIDEMIOLOGY Treatement Progno-sis
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Perinea Trauma during Childbirth: Socio Demographical Aspect and Management at Obstetrical Gynecology Department Donka National Hospital (Guinea-Conakry) 预览
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作者 O. Baldé M. H. Diallo +6 位作者 I. Sylla M. N. Mamy A. B. Barry I. S. Baldé A. D. Diallo M. D. Baldé N. Keita 《妇产科期刊(英文)》 2019年第11期1486-1491,共6页
Perineal trauma is a non-surgical solution of continuity of posterior perineal committing under the effect of a violent exertion during childbirth. It occurs at the time of disengagement, either from the head or the p... Perineal trauma is a non-surgical solution of continuity of posterior perineal committing under the effect of a violent exertion during childbirth. It occurs at the time of disengagement, either from the head or the posterior shoulder. Objectives: To calculate the perinea trauma during childbirth, describe the socio demographic profile of the women in childbed, identify contributory effects and appreciate the maternal prognostic. Methodology: It was a prospective study, descriptive type of 6 months (from May 19 to November 20, 2014). It took place at the maternity ward of Donka National Hospital. It concerned all received parturient, women in bed of a single fetus in the unit and having had a perineum traumatism. The real ones were epidemiologic, therapeutic clinical and prognostic. Results: We have recorded 110 perinea traumatism cases over 3496 childbirth let say a frequency of 3%. The socio demographic profile of the woman who did perinea traumatism was a teenager (42.7%), professional occupation (29.1%), married (88.2%), schooled, secondary and Technical level (42.7%), primary (70%) having had more than 3 prenatal consultations (73.6%). Contributory effects were: prim parity, young age, instrumental extraction by obstetrical forceps and the fetal weight between 2500 to 3999 g. Surgical management was (100%). The following were simple in 88.2% cases versus 11. 8% of complications. Conclusion: The reduction of this frequency requests systematical practice and corrects recentered prenatal consultations and the respect of episiotomy indications. 展开更多
关键词 Perinea Traumatism Epidemiology MANAGEMENT Donka
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Endometrial Hyperplasia: Epidemiological Profile of Patients and Anatomical and Clinical Aspects of Lesions at Conakry University Hospital 预览
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作者 M. C. Diallo E. M. Bah +7 位作者 B. A. Diallo I. K. Bah A. Diallo O. Baldé A. Sylla A. Baldé I. S. Baldé A. B. Diallo 《妇产科期刊(英文)》 2019年第2期260-266,共7页
Summary: Estimate the incidence of endometrial hyperplasia according to socio-demographic parameters and the type of lesions histological. Methodology: This was a retrospective, and 15-year descriptive study from Janu... Summary: Estimate the incidence of endometrial hyperplasia according to socio-demographic parameters and the type of lesions histological. Methodology: This was a retrospective, and 15-year descriptive study from January 1, 2000 to December 31, 2014 conducted at the Department of Anatomy and Pathological Cytology of the National Hospital Donka in collaboration with the obstetric gynecology departments of the Conakry University Hospital. Results: We collected 296 cases of malignant and benign endometrial hyperplasia in 15 years, accounting for 37% of all endometrial biopsy curettages examined. The age group 47 to 56 years was the most affected (81 cases) or 27, 36%. The mean age was 53.6 years with extremes of 27 and 83 years. Metrorrhagia was the main reason for consultation (206 cases), i.e. 69.59%. The suspicion of endometrial hyperplasia by physicians was the most frequently diagnosed circumstance (149 cases) or 50.33%. Biopsy curettage was the most frequently used method (176 cases), is 59.45%. Histological endometrial lesions of atypical complex adenomatous hyperplasia (79 cases) represented 26.69%. Benign behavior was most frequently observed in (235 cases) or 79.39%. Conclusion: Endometrial hyperplasia is an endometrial lesion whose atypical histological types represent the borderline lesions between benignity and malignancy. 展开更多
关键词 ENDOMETRIAL HYPERPLASIA EPIDEMIOLOGY Anatomoclinical CHU Conakry
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