基金This study was supported by the Jiangsu Provincial Medical Youth Talent of the Project of Invigorating Health Care through Science, Technology and Education （Grant No. QNRC2016694） the Six Talents Peak Project of Jiangsu Province （Grant No. 2015-WSN-061）+1 种基金 the fifth ＇226＇ High Level Talent Training Project of Nantong City, the National Natural Science Foundation of China （Grant No. 81502867） and the Technology Innovation Programme of Nantong University （Grant No. YKS14017）.