基金This work was supported by the National Natural Science Foundation of China, No. 31040043, 31671248 （to NH）, No. 81171146, 81372044, 30971526 （to BGD the Chinese National Ministry of Science and Technology （973 Project）, No. 2014CB542201 （to PXZ）+4 种基金 the Ministry of Education Innovation Team, China, No. 1RT1201 （to PXZ） the Fostering Young Scholars of Peking University Health Science Center, China, No. BMU2017PY013 （to PXZ） the Chinese National General Program of National Natural Science Fund, China （to PXZ） the Beijing City Science ＆ Technology New Star Cross Project, China, No. 2018019 （to PXZ） the National Natural Science Foundation of China, No. 31771322, 31571235, 51373023, 21171019, 31640045, 31571236, 31471144, 31100860, 31371210 （to PXZ）. The funders did not partici- pate in data collection and analysis, article writing or submission.
基金This study was supported by the High Levels of Health Technical Personnel in Beijing City Health System of China, No. 2013-3-050 （to ]ZY）. The funding source had no role in study conception and design, data analysis or interpretation, paper writing or deciding to submit this paper for publication.