基金This work was supported by the grants from the National Natural Science Foundation of China （Nos. 81671489, 81372480, and 81602728）, the Postdoctoral Foundation of Jiangsu （No. 1401017A）, the Special Postdoctoral Foundation of China （No. 2015T80570）, the First Grade Postdoctoral Foundation of China （No. 2014M560437）, the Foundation of Six Talent Peaks Project of Jiangsu Province （No. 2014-WSW-059）, and the Foundation of Wuxi City Health and Family Planning （Nos. MS201501 and Q201505）.