该文介绍了一种应用于电机故障监测的振动信号采集系统。针对所用数据采集卡的配套软件使用复杂、功能不足等问题,在Windows系统Visual Studio 2019开发环境下,基于C#语言和采集卡的API函数,重新开发采集卡上位机软件,实现了对电机振动...该文介绍了一种应用于电机故障监测的振动信号采集系统。针对所用数据采集卡的配套软件使用复杂、功能不足等问题,在Windows系统Visual Studio 2019开发环境下,基于C#语言和采集卡的API函数,重新开发采集卡上位机软件,实现了对电机振动信号的采样、波形显示、数据存储,以及在高速采集模式下的信号异常报警功能。通过电机振动信号采集试验,对软件的相关功能进行测试,证明该软件功能正常,运行稳定,性能较好,满足电机故障监测的需求。展开更多
BACKGROUND Hepatitis C virus(HCV)infection is a public health concern worldwide.Several factors,including genetic polymorphisms,may be evolved in the progression of HCV infection to liver diseases.Interferon lambdas(I...BACKGROUND Hepatitis C virus(HCV)infection is a public health concern worldwide.Several factors,including genetic polymorphisms,may be evolved in the progression of HCV infection to liver diseases.Interferon lambdas(IFNLs)modulate the immune response during viral infections.IFNLs induce antiviral activity,interfering in the viral replication by promoting the expression of several genes that regulate immunological functions.The interferon lambda-4(IFNL4)rs12979860 polymorphism,which is characterized by a C to T transition in intron 1,is associated with spontaneous and treatment-induced clearance of HCV infection and may play a role in the development of HCV-associated liver diseases,including hepatocellular carcinoma(HCC).AIM To investigate the association of IFNL4 rs12979860 polymorphism with fibrosis,cirrhosis,and HCC in patients with chronic HCV infection.METHODS This study was comprised of 305 chronic HCV-infected patients(53 fibrosis,154 cirrhosis,and 98 HCC cases).The control group was comprised of 260 HCVnegative healthy individuals.The IFNL4 rs12979860 polymorphism was genotyped using the TaqMan assay.Fibrosis was diagnosed based on liver biopsy findings,while cirrhosis was diagnosed through clinical,laboratory,anatomopathological,and/or imaging data.HCC was diagnosed through imaging tests,tumor,and/or anatomopathological markers.RESULTS The T allele was observed in the three groups of patients(fibrosis,cirrhosis,and HCC)at a significantly higher frequency when compared with the control group(P=0.047,P<0.001,and P=0.01,respectively).Also,genotype frequencies presented significant differences between the control group and cirrhosis patients(P<0.001)as well as HCC patients(P=0.002).The risk analysis was performed using the codominant and dominant T allele models.In the codominant model,it was observed that the CT genotype showed an increased risk of developing cirrhosis in comparison with the CC genotype[odds ratio(OR)=2.53;95%confidence interval(CI):1.55-4.15;P<0.001]as well as with HCC(OR=2.54;95%CI:1.44-4.56;P=0.001).A similar result was observed in the comparison of the TT vs CC genotype between the control group and cirrhosis group(OR=2.88;95%CI:1.44-5.77;P=0.001)but not for HCC patients.In the dominant T allele model,the CT+TT genotypes were associated with an increased risk for progression to cirrhosis(OR=2.60;95%CI:1.63-4.19;P<0.001)and HCC(OR=2.45;95%CI:1.42-4.31;P=0.001).CONCLUSION These findings suggest that the T allele of IFNL4 rs12979860 polymorphism is associated with the development of cirrhosis and HCC in chronic HCV-infected patients.展开更多
深度学习在地质学领域有了越来越多的应用。在测井领域,可以利用深度学习方法更好地进行岩性分析、断层和裂隙识别等。测井数据最常用的数据格式是Las格式,而目前深度学习应用程序包不能直接对Las文件进行读取,因此存在数据间格式转换问...深度学习在地质学领域有了越来越多的应用。在测井领域,可以利用深度学习方法更好地进行岩性分析、断层和裂隙识别等。测井数据最常用的数据格式是Las格式,而目前深度学习应用程序包不能直接对Las文件进行读取,因此存在数据间格式转换问题,需要将测井Las文件转化为能直接被程序包读取的数据格式。借助Visual Studio 2012平台,运用C#语言设计开发了一个LastoCSV格式转换软件,该软件能够对Las测井文件进行读取、分析、存储,然后转换为能被深度学习应用程序包直接读取的CSV格式文件,并且可对无效数据进行剔除处理。实验结果表明,该软件能快速准确地对数据进行处理并转换成CSV格式文件。展开更多
文摘该文介绍了一种应用于电机故障监测的振动信号采集系统。针对所用数据采集卡的配套软件使用复杂、功能不足等问题,在Windows系统Visual Studio 2019开发环境下,基于C#语言和采集卡的API函数,重新开发采集卡上位机软件,实现了对电机振动信号的采样、波形显示、数据存储,以及在高速采集模式下的信号异常报警功能。通过电机振动信号采集试验,对软件的相关功能进行测试,证明该软件功能正常,运行稳定,性能较好,满足电机故障监测的需求。
基金Supported by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-Brasil(CAPES),No.001.
文摘BACKGROUND Hepatitis C virus(HCV)infection is a public health concern worldwide.Several factors,including genetic polymorphisms,may be evolved in the progression of HCV infection to liver diseases.Interferon lambdas(IFNLs)modulate the immune response during viral infections.IFNLs induce antiviral activity,interfering in the viral replication by promoting the expression of several genes that regulate immunological functions.The interferon lambda-4(IFNL4)rs12979860 polymorphism,which is characterized by a C to T transition in intron 1,is associated with spontaneous and treatment-induced clearance of HCV infection and may play a role in the development of HCV-associated liver diseases,including hepatocellular carcinoma(HCC).AIM To investigate the association of IFNL4 rs12979860 polymorphism with fibrosis,cirrhosis,and HCC in patients with chronic HCV infection.METHODS This study was comprised of 305 chronic HCV-infected patients(53 fibrosis,154 cirrhosis,and 98 HCC cases).The control group was comprised of 260 HCVnegative healthy individuals.The IFNL4 rs12979860 polymorphism was genotyped using the TaqMan assay.Fibrosis was diagnosed based on liver biopsy findings,while cirrhosis was diagnosed through clinical,laboratory,anatomopathological,and/or imaging data.HCC was diagnosed through imaging tests,tumor,and/or anatomopathological markers.RESULTS The T allele was observed in the three groups of patients(fibrosis,cirrhosis,and HCC)at a significantly higher frequency when compared with the control group(P=0.047,P<0.001,and P=0.01,respectively).Also,genotype frequencies presented significant differences between the control group and cirrhosis patients(P<0.001)as well as HCC patients(P=0.002).The risk analysis was performed using the codominant and dominant T allele models.In the codominant model,it was observed that the CT genotype showed an increased risk of developing cirrhosis in comparison with the CC genotype[odds ratio(OR)=2.53;95%confidence interval(CI):1.55-4.15;P<0.001]as well as with HCC(OR=2.54;95%CI:1.44-4.56;P=0.001).A similar result was observed in the comparison of the TT vs CC genotype between the control group and cirrhosis group(OR=2.88;95%CI:1.44-5.77;P=0.001)but not for HCC patients.In the dominant T allele model,the CT+TT genotypes were associated with an increased risk for progression to cirrhosis(OR=2.60;95%CI:1.63-4.19;P<0.001)and HCC(OR=2.45;95%CI:1.42-4.31;P=0.001).CONCLUSION These findings suggest that the T allele of IFNL4 rs12979860 polymorphism is associated with the development of cirrhosis and HCC in chronic HCV-infected patients.
文摘深度学习在地质学领域有了越来越多的应用。在测井领域,可以利用深度学习方法更好地进行岩性分析、断层和裂隙识别等。测井数据最常用的数据格式是Las格式,而目前深度学习应用程序包不能直接对Las文件进行读取,因此存在数据间格式转换问题,需要将测井Las文件转化为能直接被程序包读取的数据格式。借助Visual Studio 2012平台,运用C#语言设计开发了一个LastoCSV格式转换软件,该软件能够对Las测井文件进行读取、分析、存储,然后转换为能被深度学习应用程序包直接读取的CSV格式文件,并且可对无效数据进行剔除处理。实验结果表明,该软件能快速准确地对数据进行处理并转换成CSV格式文件。