期刊文献+
共找到64,477篇文章
< 1 2 250 >
每页显示 20 50 100
A rare case of non-ST-segment elevation myocardial infarction triggered by coronary subclavian steal syndrome 预览
1
作者 Xiao-Qing CAI Feng TIAN +7 位作者 Shan-Shan ZHOU Jing JING Wei HU Tao ZHANG Xi WANG Ri-Na DU Qiang XU Yun-Dai CHEN 《老年心脏病学杂志:英文版》 SCIE CAS CSCD 2019年第4期378-380,共3页
Coronary subclavian steal syndrome (CSSS) has been recognized lately as an unusual clinical entity,giving rise to angina but rarely causing an acute coronary syndrome (ACS). The prerequisites for the appearance of CSS... Coronary subclavian steal syndrome (CSSS) has been recognized lately as an unusual clinical entity,giving rise to angina but rarely causing an acute coronary syndrome (ACS). The prerequisites for the appearance of CSSS are both a patent left internal mammary artery (LIMA) graft and severe stenosis of the left subclavian artery (LSA). However,LSA is often overlooked in the diagnostic evaluation of patients with angina,who have underwent coronary artery bypass grafting (CABG). We report an unusual case of non-ST-segment elevation myocardial infarction (NSTEMI) caused by subtotal occlusion of proximal LSA. 展开更多
关键词 Acute CORONARY SYNDROME CORONARY artery BYPASS GRAFTING CORONARY SUBCLAVIAN steal SYNDROME PERCUTANEOUS CORONARY intervention
在线阅读 下载PDF
Impact of gout on in-hospital outcomes of acute coronary syndromerelated hospitalizations and revascularizations: Insights from the national inpatient sample 预览
2
作者 Rupak Desai Tarang Parekh +7 位作者 Hemant Goyal Hee Kong Fong Dipen Zalavadia Nanush Damarlapally Rajkumar Doshi Sejal Savani Gautam Kumar Rajesh Sachdeva 《世界心脏病学杂志:英文版(电子版)》 2019年第5期137-148,共12页
BACKGROUND Previous studies have established a role of gout in predicting risk and prognosis of cardiovascular diseases. However, large-scale data on the impact of gout on inpatient outcomes of acute coronary syndrome... BACKGROUND Previous studies have established a role of gout in predicting risk and prognosis of cardiovascular diseases. However, large-scale data on the impact of gout on inpatient outcomes of acute coronary syndrome (ACS)-related hospitalizations and post-revascularization is inadequate. AIM To evaluate the impact of gout on in-hospital outcomes of ACS hospitalizations, subsequent healthcare burden and predictors of post-revascularization inpatient mortality. METHODS We used the national inpatient sample (2010-2014) to identify the ACS and goutrelated hospitalizations, relevant comorbidities, revascularization and postrevascularization outcomes using the ICD-9 CM codes. A multivariable analysis was performed to evaluate the predictors of post-revascularization in-hospital mortality. RESULTS We identified 3144744 ACS-related hospitalizations, of which 105198 (3.35%) also had gout. The ACS-gout cohort were more often older white males with a higher prevalence of comorbidities. Coronary artery bypass grafting was required more often in the ACS-gout cohort. Post-revascularization complications including cardiac (3.2% vs 2.9%), respiratory (3.5% vs 2.9%), and hemorrhage (3.1% vs 2.7%) were higher whereas all-cause mortality was lower (2.2% vs 3.0%) in the ACSgout cohort (P < 0.001). An older age (OR 15.63, CI: 5.51-44.39), non-elective admissions (OR 2.00, CI: 1.44-2.79), lower household income (OR 1.44, CI: 1.17- 1.78), and comorbid conditions predicted higher mortality in ACS-gout cohort undergoing revascularization (P < 0.001). Odds of post-revascularization inhospital mortality were lower in Hispanics (OR 0.45, CI: 0.31-0.67) and Asians (OR 0.65, CI: 0.45-0.94) as compared to white (P < 0.001). However, postoperative complications significantly raised mortality odds. Mean length of stay, transfer to other facilities, and hospital charges were higher in the ACS-gout cohort. CONCLUSION Although gout was not independently associated with an increased risk of postrevascularization in-hospital mortality in ACS, it di 展开更多
关键词 GOUT Serum uric acid Acute CORONARY syndrome Unstable angina Myocardial infarction Revascularization Percutaneous CORONARY intervention CORONARY artery bypass grafting IN-HOSPITAL OUTCOMES
在线阅读 免费下载
Impact of main vessel calcification on procedural and clinical outcomes of bifurcation lesion undergoing provisional single-stenting intervention:a multicenter,prospective,observational study 预览
3
作者 Jing BAI Yan YUE +14 位作者 Hong-Qi FENG Shu-Xin HAO Liang PENG Ming ZHANG Shaheena Nazneen Li-Feng LIU Zhe TANG Xiao-Lin YU Yu-Tao XIE Fu-Xiang SHAN Ming-Zhi SHEN Jiang-Tao WANG Xue-Hua WAN Yun-Dai CHEN Yu WANG 《老年心脏病学杂志:英文版》 SCIE CAS CSCD 2019年第2期156-163,共8页
Background Few data on the combined effects of bifurcation and calcification on coronary artery disease(CAD)patients undergoing percutaneous coronary intervention(PCI)are available.This study evaluated the impact of m... Background Few data on the combined effects of bifurcation and calcification on coronary artery disease(CAD)patients undergoing percutaneous coronary intervention(PCI)are available.This study evaluated the impact of main vessel(MV)calcification on the procedural and long-term outcomes in patients with CAD who underwent provisional single stent PCI.Methods This is a multicenter,prospective,observational study.Patients with bifurcation lesions were enrolled at 10 PCI centers in China from January 2015 to December 2017.Intravascular ultrasound or optical coherence tomography was performed in all patients to evaluate the MV calcification.Patients were treated with provisional single stent strategy using drug eluting stents and followed-up at 1 month,6 months and 12 months after discharge by telephone contact or outpatient visit.Repeated coronary imaging was performed within one year.We compared the procedural success rates in MV and in side branch(SB),and target lesion failure(TLF),defined as a composite of cardiac death,non-fatal myocardial infarction,definite or possible stent thrombosis and target lesion revascularization between patients with and without MV calcification.Results A total of 185 subjects were enrolled according to the inclusion and exclusion criteria of this study.MV calcification was detected in 119(64.3%,calcification group)and not found in 66(35.7%,non-calcification group)patients.The angiographic success rate of MV was 95.8%in the calcification group and 97.0%in the non-calcification group(P=0.91);the angiographic success rate of SB was 32.8%in the calcification group and 53.0%in the non-calcification group(P<0.05).During the one-year follow-up period,TLF occurred in 14(11.8%)patients in the calcification group and in 13(19.7%)in the non-calcification group{P=0.31).Multivariate regression analysis showed the same result(HR=1.23,95%CI:0.76-1.52,P=0.47).Calcification on group had higher recurrent angina than non-calcification group(13.51%vs.17.65%,P<0.05).Conclusions In patients with coronary bif 展开更多
关键词 Bifurcation lesion CORONARY artery disease CORONARY calciflcation Percutaneous CORONARY INTERVENTION
在线阅读 下载PDF
单支架术在冠状动脉左主干病变治疗中的应用评价 预览
4
作者 王学斌 赵良平 +5 位作者 姚彪 陈聿奇 王茂松 罗显元 徐卫亭 陈建昌 《安徽医药》 CAS 2019年第4期683-687,共5页
目的评价冠状动脉左主干(LMCA)病变病人接受单支架术的治疗效果及预后。方法收集2007年1月至2014年3月在苏州大学附属第二医院接受经皮冠状动脉介入治疗(PCI)的53例LMCA病变病人的临床资料,所有入选病人均完成了冠状动脉单支架植入术。... 目的评价冠状动脉左主干(LMCA)病变病人接受单支架术的治疗效果及预后。方法收集2007年1月至2014年3月在苏州大学附属第二医院接受经皮冠状动脉介入治疗(PCI)的53例LMCA病变病人的临床资料,所有入选病人均完成了冠状动脉单支架植入术。随访病人术后1年、术后2年时主要不良心脑血管事件(MACCE)发生情况。结果手术成功率100%。23例在PCI术后1—12月行冠状动脉造影复查,2例发生支架内再狭窄,再狭窄率为8.7%。术后1年、术后2年时总体MACCE发生率分别为7.5%、9.4%。PCI术后1年、2年,SYNTAX积分低、中分组(≤32)和高分组(≥33)间无MACCE生存率比较,差异无统计学意义(分别为90.5%、100.0%,P=0.297;90.5%、90.9%,P=0.931)。结论 对经选择的LMCA病变病人,包括部分无保护左主干病变及分叉病变病人,单支架术成功率高,中远期预后良好。 展开更多
关键词 血管成形术 气囊 冠状动脉 冠状动脉疾病 药物洗脱支架 冠状血管造影术 预后
在线阅读 下载PDF
Novel Imaging Approaches for the Diagnosis of Stable Ischemic Heart Disease in Women 预览
5
作者 Viviany R.Taqueti,MD,MPH 《心血管创新与应用》 2019年第B02期375-389,共15页
Conventional recommendations for diagnostic testing for the evaluation of stable ischemic heart disease in women have largely paralleled those in men.Although they are designed primarily for the identifi cation of obs... Conventional recommendations for diagnostic testing for the evaluation of stable ischemic heart disease in women have largely paralleled those in men.Although they are designed primarily for the identifi cation of obstructive coronary artery disease(CAD),traditional approaches can lead to overtesting in women without differentiating who is truly at risk.Several unique factors related to the presentation,diagnosis,and underlying pathophysiology of stable ischemic heart disease in women necessitate a more specific approach to the assessment of their risk,complete with separate guidelines when appropriate.This overview highlights how advanced noninvasive imaging tools,including cardiac computed tomography angiography,positron emission tomography,and cardiac magnetic resonance imaging,are enabling very sensitive assessments of anatomic atherosclerotic plaque burden,macrovessel-and microvessel-related ischemia,and myocardial fi brosis,respectively.Moving forward,effective diagnostic testing will need to identify women at high risk of adverse cardiovascular events(not anatomically obstructive CAD per se)without overtesting those at low risk.Judicious application of novel imaging approaches will be critical to broadening the defi nitions of CAD and ischemia to better refl ect the whole spectrum of pathological phenotypes in women,including nonobstructive CAD and coronary microvascular dysfunction,and aid in the development of needed evidence-based strategies for their management. 展开更多
关键词 CORONARY MICROVASCULAR dysfunction nonobstructive CORONARY artery DISEASE stable ischemic HEART DISEASE HEART DISEASE in WOMEN cardiovascular IMAGING positron emission tomography
在线阅读 免费下载
Emerging Techniques for Cardiovascular PET 预览
6
作者 Austin A.Robinson,MD Jamieson M.Bourque,MD,MHS 《心血管创新与应用》 2019年第B04期13-24,共12页
Positron emission tomography(PET)has been successfully applied to an increasing number of cardiovascular conditions.This review will highlight the status of cardiovascular PET,including the present state of the art an... Positron emission tomography(PET)has been successfully applied to an increasing number of cardiovascular conditions.This review will highlight the status of cardiovascular PET,including the present state of the art and the expanding pool of clinical evidence guiding its use.Additionally,we highlight upcoming developments in the fi eld,including the development of new tracers and applications of PET to novel indications within cardiovascular medicine. 展开更多
关键词 POSITRON emission tomography(PET) absolute blood fl ow metabolic imaging novel tracers CORONARY artery disease(CAD) CORONARY MICROVASCULAR DYSFUNCTION cardiac infection CONGESTIVE heart failure
在线阅读 免费下载
Successful opening in-stent chronic total occlusion lesion of coronary artery by excimer laser coronary angioplasty 预览
7
作者 Jing BAI Hai-Xia WANG +7 位作者 Jiang-Tao WANG Jing ZHAO Liang PENG Xue-Dong YANG Zhe TANG Shaheena Nazneen Gao-Kun WANG Yu WANG 《老年心脏病学杂志:英文版》 SCIE CAS CSCD 2019年第6期502-506,共5页
In percutaneous coronary intervention (PCI), chronic total occlusion (CTO) coronary artery disease still remains difficult to treat. One of the reasons for the failure is the hard of the CTO lesions that balloon is di... In percutaneous coronary intervention (PCI), chronic total occlusion (CTO) coronary artery disease still remains difficult to treat. One of the reasons for the failure is the hard of the CTO lesions that balloon is difficult to pass through or expand. Previous methods to deal with CTO lesions that cannot be passed by balloon, include selecting reinforced catheter (such as 5 in 6 guiding catheter, Guidzilla catheter, or Tornus microcatheter), guidewire extrusion or rotary grinding technology. In recent years, excimer laser coronary angioplasty (ELCA) has been gradually applied to CTO lesions. Using inert halide as the laser medium, ELCA emits a 308 nm high-intensity unidirectional light wave with absorption depth of only 50 μmL, resulting in less thermal effect and less damage to non-target lesions. In this paper, we will describe a successful PCI case of an in-stent CTO lesion using ELCA with long term coronary angiography follow-up. 展开更多
关键词 Chronic total OCCLUSION Drug coating BALLOON EXCIMER laser CORONARY ANGIOPLASTY Percutaneous CORONARY intervention
在线阅读 下载PDF
Giant Aneurysm of a Coronary-Pulmonary Artery Fistula:A Rare Cause of a Diastolic Murmur 预览
8
作者 Andreas Seitz Sophie Schafer +2 位作者 Maik Backes Heiko Mahrholdt Peter Ong 《心血管创新与应用》 2019年第B07期143-145,共3页
A coronary-pulmonary artery fistula with giant aneurysmal dilatation is an extremely rare clinical constellation.The natural course of this disease and the incidence of complications are unknown.Hence,optimal treatmen... A coronary-pulmonary artery fistula with giant aneurysmal dilatation is an extremely rare clinical constellation.The natural course of this disease and the incidence of complications are unknown.Hence,optimal treatment,particularly in asymptomatic patients,is still a matter of debate.Here we report a case of a 71-year-old asymptomatic woman with a diastolic murmur.Comprehensive cardiovascular assessments including cardiac computed tomography and invasive coronary angiography revealed a coronary-pulmonary artery fi stula with giant aneurysmal dilatation.The patient was managed conservatively and has now been followed up for 5 years without any events. 展开更多
关键词 CORONARY ANOMALY CORONARY FISTULA giant ANEURYSM PULMONARY artery DIASTOLIC murmur
在线阅读 免费下载
高峰射血率及高峰充盈率在急性心肌梗死后左心室收缩功能不全患者预后评估中的价值
9
作者 徐显海 郭小闪 +2 位作者 靳春荣 武志芳 李思进 《中华核医学与分子影像杂志》 CAS 北大核心 2019年第5期272-277,共6页
目的探讨高峰射血率(PER)及高峰充盈率(PFR)预测急性心肌梗死(AMI)后左心室收缩功能不全(LVSD)患者预后的临床价值。方法回顾性分析2014年1月至2015年12月在AMI血运重建术后出现LVSD的123例患者[男103例、女20例,年龄(60.6±11.2)岁... 目的探讨高峰射血率(PER)及高峰充盈率(PFR)预测急性心肌梗死(AMI)后左心室收缩功能不全(LVSD)患者预后的临床价值。方法回顾性分析2014年1月至2015年12月在AMI血运重建术后出现LVSD的123例患者[男103例、女20例,年龄(60.6±11.2)岁]。患者均行99Tcm-甲氧基异丁基异腈(MIBI)门控心肌灌注断层显像(GSMPI)。通过定量灌注SPECT(QPS)软件分析心肌灌注图像,获得总静息评分(SRS)和总灌注缺损面积(TPD);通过定量门控SPECT(QGS)软件分析左心室功能参数,包括左心室射血分数(LVEF)、舒张末期容积(EDV)、收缩末期容积(ESV)、PER及PFR。收集一般临床资料并随访患者[中位随访时间27(范围:9~50)个月],以发生心血管事件为随访终点。对PER和PFR进行Pearson相关分析,通过受试者工作特征(ROC)曲线获得预测心血管事件发生的PER及PFR最佳阈值,并采用Kaplan-Meier生存曲线和Cox回归模型对患者进行分析。结果PER和PFR两者之间高度相关(r=-0.931,P<0.001),两者预测心血管事件发生的最佳阈值分别为-1.10和1.09 EDV/s。Kaplan-Meier生存分析示-PER≤1.10 EDV/s组(48例)无心血管事件发生生存率较-PER>1.10 EDV/s(75例)明显减低(16.7%与66.7%;χ^2=60.096,P<0.001);PFR≤1.09 EDV/s组(50例)无心血管事件发生生存率较PFR>1.09 EDV/s(73例)明显减低(16.0%与68.5%;χ^2=74.771,P<0.001)。Cox多因素分析示PER[风险比(HR)=0.40,95% CI: 0.20~0.83)及PFR(HR=0.22,95% CI: 0.12~0.47)是影响本组患者发生心血管事件的独立预后因素。结论AMI血运重建术后LVSD患者PER及PFR高度相关,且对心血管事件的发生有独立预测价值。 展开更多
关键词 心肌梗塞 心室功能障碍 血管成形术 气囊 冠状动脉 冠状动脉旁路移植术 非体外循环 预后 心肌灌注显像 99M锝甲氧基异丁基异腈
Application of virtual histological intravascular ultrasound in plaque composition assessment of saphenous vein graft diseases
10
作者 Jing Gao Yue-Ying Wang Yin Liu 《中华医学杂志:英文版》 SCIE CAS CSCD 2019年第8期957-962,共6页
Objective:Saphenous vein grafts disease(SVGD)is a common complication after coronary artery bypass graft(CABG)and normally treated by percutaneous coronary intervention(PCI).The most common complication after SVG-PCI ... Objective:Saphenous vein grafts disease(SVGD)is a common complication after coronary artery bypass graft(CABG)and normally treated by percutaneous coronary intervention(PCI).The most common complication after SVG-PCI is slow or no-reflow.It is known that the no-reflow phenomenon occurs in up to 15%of the SVG-PCI and is associated with high risk of major adverse cardiac events(MACEs)and mortality,therefore,it is important to investigate the factors that could predict the clinical outcome of PCI for risk stratification and guiding interventions.In recent years,the spectral analysis of intravascular ultrasound(IVUS)radiofrequency data(virtual histology-IVUS[VH-IVUS])has been used to provide quantitative assessment on both plaque compositions and morphologic characteristics.Data sources:The PubMed,Embase,and Central databases were searched for possible relevant studies published from 1997 to 2018 using the following index keywords:“Coronary artery bypass grafting,”“Saphenous venous graft disease,”“Virtual histologyintravascular ultrasound,”“Virtual histology-intravascular ultrasound,”and“Percutaneous coronary intervention.”Study selection:The primary references were Chinese and English articles including original studies and literature reviews,were identified and reviewed to summarize the advances in the application of VH-IVUS techniques in situ vascular and venous graft vascular lesions.Results:With different plaque components exhibiting a defined spectrum,VH-IVUS can classify atherosclerotic plaque into four types:fibrous tissue(FT),fibro fatty(FF),necrotic core(NC),and dense calcium(DC).The radiofrequency signal is mathematically transformed into a color-coded representation,including lipid,fibrous tissue,calcification,and necrotic core.Several studies have demonstrated the independent relationship between VH-IVUS-defined plaque classification or plaque composition and MACEs,but a significant association between plaque components and no-reflow after PCI in acute coronary syndrome.In recent year 展开更多
关键词 CORONARY artery bypass grafting Saphenous VENOUS graft disease VIRTUAL histology-intravascular ultrasound Percutaneous CORONARY intervention
Multivessel coronary artery ectasia and severe calcification in a patient with pheochromocytoma:a case report 预览
11
作者 Daokuo Yao Xiangyu Gao +2 位作者 Huiqiang Zhao Hui Chen Lexin Wang 《生物医学研究杂志:英文版》 CAS CSCD 2019年第1期69-72,共4页
Multivessel coronary artery ectasia with severe calcification is rare among patients with coronary artery disease. A 74-year-old Chinese woman suffered from acute myocardial infarction on a background of 50 years of p... Multivessel coronary artery ectasia with severe calcification is rare among patients with coronary artery disease. A 74-year-old Chinese woman suffered from acute myocardial infarction on a background of 50 years of poorly controlled hypertension secondary to pheochromocytoma, which was surgically removed in June 2012 prior to the presentation. Coronary angiography revealed total occlusion of the proximal left anterior descending artery, and multiple ectasias with severe calcification in the left main, circumflex and right coronary artery. After an aspiration thrombectomy and balloon angioplasty, grade 3 coronary flow was restored in the left descending coronary artery. No cardiac events were found in the 12-month follow-up. We conclude that multivessel coronary artery ectasia and severe calcification may be present in patients with a long-standing history of hypertension secondary to pheochromocytoma. 展开更多
关键词 myocardial INFARCTION CORONARY artery ECTASIA percutaneous CORONARY intervention PHEOCHROMOCYTOMA hypertension
在线阅读 免费下载
Selective Coronary Angiography Following Cardiac Arrest 预览
12
作者 Jayasheel O.Eshcol Adnan K.Chhatriwalla 《心血管创新与应用》 2019年第B07期85-98,共14页
Sudden cardiac arrest is a major cause of death predominantly caused by ventricular tachyarrhythmia in patients with coronary artery disease.Despite advancements in resuscitation care,the rate of survival after cardia... Sudden cardiac arrest is a major cause of death predominantly caused by ventricular tachyarrhythmia in patients with coronary artery disease.Despite advancements in resuscitation care,the rate of survival after cardiac arrest remains low.There is a growing body of observational data suggesting early coronary angiography reduces delay to revascularization and may improve outcomes.Most survivors present comatose,and neurologic outcome is uncertain;therefore it is often challenging to identify patients who will benefit from early coronary angiography.Several variables and risk scores that predict a favorable neurologic outcome have been identified.The rationale and current evidence for early angiography are reviewed,and a suggested approach to the selection of patients is presented. 展开更多
关键词 CARDIAC ARREST CORONARY ANGIOGRAPHY PERCUTANEOUS CORONARY INTERVENTION
在线阅读 免费下载
Risk stratification for coronary artery disease in multi-ethnic populations:Are there broader considerations for cost efficiency? 预览
13
作者 Pupalan Iyngkaran William Chan +5 位作者 Danny Liew Jalal Zamani John D Horowitz Michael Jelinek David L Hare James A Shaw 《世界方法学杂志》 2019年第1期1-19,共19页
Coronary artery disease(CAD)screening and diagnosis are core cardiac specialty services.From symptoms,autopsy correlations supported reductions in coronary blood flow and dynamic epicardial and microcirculatory corona... Coronary artery disease(CAD)screening and diagnosis are core cardiac specialty services.From symptoms,autopsy correlations supported reductions in coronary blood flow and dynamic epicardial and microcirculatory coronaries artery disease as etiologies.While angina remains a clinical diagnosis,most cases require correlation with a diagnostic modality.At the onset of the evidence building process much research,now factored into guidelines were conducted among population and demographics that were homogenous and often prior to newer technologies being available.Today we see a more diverse multi-ethnic population whose characteristics and risks may not consistently match the populations from which guideline evidence is derived.While it would seem very unlikely that for the majority,scientific arguments against guidelines would differ,however from a translational perspective,there will be populations who differ and importantly there are cost-efficacy questions,e.g.,the most suitable first-line tests or what parameters equate to an adequate test.This article reviews non-invasive diagnosis of CAD within the context of multi-ethnic patient populations. 展开更多
关键词 Cost efficacy CORONARY artery DISEASE CORONARY heart DISEASE ETHNICITY Outcomes Risk STRATIFICATION
在线阅读 免费下载
Invasive strategy in elderly patients with acute coronary syndrome in 2018:close to the truth? 预览
14
作者 Sergio Garcia-Blas Clara Bonanad Juan Sanchis 《老年心脏病学杂志:英文版》 SCIE CAS CSCD 2019年第2期114-120,共7页
Elderly population constitutes an increasingly larger proportion of patients admitted for acute coronary syndromes(ACS).The optimal management of ACS in these patients is still a challenge due to their clinical peculi... Elderly population constitutes an increasingly larger proportion of patients admitted for acute coronary syndromes(ACS).The optimal management of ACS in these patients is still a challenge due to their clinical peculiarities and the paucity of specific data,and they have been traditionally managed more conservatively mainly based on subjective criteria.In ST^segment elevation acute myocardial infarction urgent reperfusion is the standard of care and there is no upper age limit.In non-ST segment elevation acute myocardial infarction evidence is controversial,incomplete and mainly focused on chronological age.While a strict conservative strategy should be avoided,routine invasive strategy may reduce the occurrence of myocardial infarction and need for revascularization at follow-up with no established benefit in terms of mortality.Clinical characteristics associated with aging,such as comorbidities and frailty,further discriminate patient's risk beyond age.Evidence is scarce,but it suggests that these features may modulate the benefit of invasive strategy in this population.Ongoing trials should clarify the optimal management of ACS based on these parameters. 展开更多
关键词 Acute CORONARY SYNDROMES COMORBIDITY FRAILTY PERCUTANEOUS CORONARY intervention The elderly
在线阅读 下载PDF
Diagnostic detection with cardiac tomography and resonance of extremely rare coronary anomaly: A case report and review of literature 预览
15
作者 Nicolò Schicchi Marco Fogante +1 位作者 Gian Marco Giuseppetti Andrea Giovagnoni 《世界临床病例杂志》 2019年第5期628-635,共8页
BACKGROUND The association of two congenital coronary artery anomalies (CAAs) is extremely rare but represents one of the main cause of sudden cardiac death in young athletes. Although coronary angiography (CX-A) is s... BACKGROUND The association of two congenital coronary artery anomalies (CAAs) is extremely rare but represents one of the main cause of sudden cardiac death in young athletes. Although coronary angiography (CX-A) is still widely used in childhood, cardiac magnetic resonance (C-MRI) and cardiac computed tomography (C-CT) have recently taken on an increasing diagnostic role in early detection of CAAs and concomitant congenital cardiac malformations. CASE SUMMARY A healthy 10-year-old male patient was referred to the Radiological Department of our Institution due to no evidence of left coronary artery in echocardiographic examination. With C-MRI was detected marked myocardial trabeculation and was suspected anomalous origin and course of left circumflex (LCx) artery and of left anterior descending (LAD) artery. With third generation Dual Source C-CT 192x2-sections (SOMATOM Force, Siemens, Germany) was confirmed anomalous origin of LCx artery from right pulmonary artery associated with anomalous origin of LAD artery from right coronary artery with course in front of right ventricular outflow tract. The patient underwent surgical treatment with reimplantation of the anomalous LCX and LAD arteries into the wall of ascending aorta, with no postoperative complications. The patient remained asymptomatic and follow-up C-MRI scan four months after operation showed complete success of surgery treatment. CONCLUSION This case highlights the diagnostic potential of C-CT and C-MRI in evaluation of CAAs and of cardiac morphology and functionality, with very low radiation dose and without the risks related to invasive procedure. 展开更多
关键词 CORONARY ANOMALIES CARDIAC computed TOMOGRAPHY CARDIAC magnetic RESONANCE Case report CORONARY artery ANOMALIES
在线阅读 免费下载
Meta-analysis on Efficacy of Yiqi Huoxue Chinese Drugs in the Treatment of Coronary Heart Disease after Coronary Revascularization 预览
16
作者 Yaonan DU Chenwei SONG +1 位作者 Areyi JIAERKEN Xiaofeng WANG 《药用植物研究(英文版)》 2019年第3期69-76,共8页
[Objectives] To make a systematic evaluation on the therapeutic efficacy and safety of Yiqi Huoxue traditional Chinese drugs combined with western medicine in treatment of coronary heart disease( CHD) after coronary r... [Objectives] To make a systematic evaluation on the therapeutic efficacy and safety of Yiqi Huoxue traditional Chinese drugs combined with western medicine in treatment of coronary heart disease( CHD) after coronary revascularization. [Methods] The literatures were retrieved from China Knowledge Infrastructure( CNKI),Chinese science and technology journal full-text database( VIP database,VIP),Wanfang Data,the Chinese biomedical Database,Pub Med,Embase,and the Cochrane Library. The retrieval time was set to the creation of the database to January 2017. The randomized controlled trial( RCT) was conducted on the comparison between Yiqi Huoxue Chinese drugs combined with western medicine and the western medicine alone in the treatment of CHD after coronary revascularization. The literature information was extracted and the methodological quality of the included literature was evaluated according to the bias risk assessment tool developed by the Cochrane Collaboration. Meta-analysis was performed with the aid of Rev Man 5. 3 software. Coronary artery restenosis rate,angina pectoris treatment efficiency,left ventricular ejection fraction( LVEF),left ventricular end-diastolic volume( LVEDV),B-type natriuretic peptide( BNP),6-minute walk test( 6 MWT),and adverse reactions were analyzed. [Results] A total of 29 articles were included,a total of2 518 patients,the literature quality was low. Meta-analysis results showed that compared with the treatment by western medicine alone,Yiqi Huoxue Chinese drugs combined with western medicine could further reduce coronary restenosis rate[RR = 0. 45,95% CI( 0. 34,0. 60),P <0. 000 01],improve the angina pectoris treatment efficiency[RR = 1. 13,95% CI( 1. 05,1. 21),P = 0. 000 5],raise LVEF[WMD = 4. 25,95% CI( 3. 46,5. 04),P < 0. 000 01],reduce LVEDV[WMD =-10. 41,95% CI(-17. 88,-2. 95),P = 0. 006],decrease the plasma BNP level[WMD =-32. 32,95% CI(-44. 92,-19. 72),P < 0. 000 01],and increase 6 MWT distance(WMD = 62. 25,95% CI( 21. 71,102. 78),P = 0. 003)[Conclusions]Yiqi Huoxue Chinese d 展开更多
关键词 CORONARY heart disease Yiqi Huoxue CHINESE DRUGS CORONARY revascularization META-ANALYSIS LEFT VENTRICULAR end fraction LEFT VENTRICULAR end-diastolic volume B-type natriuretic peptide 6-minute walk test Adverse reactions
在线阅读 免费下载
Effect of exercise rehabilitation combined with trimetazidine on endothelial function, inflammatory response and blood lipid metabolism in patients with coronary heart disease after PCI
17
作者 Li-Li Wang Yu-Mei He A-Ning Zhang 《海南医科大学学报(英文版)》 2019年第2期28-32,共5页
Objective:To study the effect of exercise rehabilitation combined with trimetazidine on endothelial function, inflammatory response and blood lipid metabolism in patients with coronary heart disease after percutaneous... Objective:To study the effect of exercise rehabilitation combined with trimetazidine on endothelial function, inflammatory response and blood lipid metabolism in patients with coronary heart disease after percutaneous coronary intervention (PCI).Methods: The patients with stable angina pectoris who received PCI in our hospital between July 2015 and November 2017 were chosen and randomly divided into the observation group who received postoperative exercise rehabilitation combined with trimetazidine and the control group who received conventional intervention combined with trimetazidine. The reactive hyperemia index (RHI) as well as serum contents of endothelial markers, inflammatory cytokines and blood lipid indexes were determined before intervention and after intervention for 3 months.Results:After intervention for 3 months, the RHI levels as well as serum NO, HDL-C and Omentin-1 contents of both groups significantly increased while serum ET-1, vWF, M-CSF, IL-6, IL-8, RANTES, LDL-C and Chemerin contents significantly decreased;the RHI level as well as serum NO, HDL-C and Omentin-1 contents of the observation group was significantly higher than those of the control group while serum ET-1, vWF, M-CSF, IL-6, IL-8, RANTES, LDL-C and Chemerin contents were significantly lower than those of the control group.Conclusion:Exercise rehabilitation combined with trimetazidine can improve the endothelial function, inhibit the inflammatory response and regulate the blood lipid metabolism in patients with coronary heart disease after PCI. 展开更多
关键词 CORONARY heart disease PERCUTANEOUS CORONARY INTERVENTION Exercise REHABILITATION ENDOTHELIAL function Inflammatory response
Plasma levels of receptor interacting protein kinase-3 correlated with coronary artery disease
18
作者 Xiao-Min Hu Xi Chen +6 位作者 Hai-Yu Pang Hong-Hong Liu Pei-Pei Chen Jing-Lin Shi Si Tang Zhi-Hong Wu Shu-Yang Zhang 《中华医学杂志:英文版》 SCIE CAS CSCD 2019年第12期1400-1405,共6页
Background: Necroptosis plays an important role in human atherosclerosis and atheroma development. Since receptor interacting protein kinase-3 (RIP3) acts as a key mediator of necroptosis, this study aimed to explore ... Background: Necroptosis plays an important role in human atherosclerosis and atheroma development. Since receptor interacting protein kinase-3 (RIP3) acts as a key mediator of necroptosis, this study aimed to explore its relationship between plasma RIP3 levels and coronary artery disease (CAD) and discover a potential new biomarker for screening CAD subtypes and severity. Methods: A total of 318 patients with CAD who had coronary angiography and 166 controls in Peking Union Medical College Hospital from September 2017 to January 2018 were enrolled in this study. Patients with CAD were divided into three subgroups: patients with stable coronary artery disease (SCAD), patients with unstable angina (UA), and patients with myocardial infarction (MI). The severity of atherosclerosis was determined by Gensini score (GSS). Logistic regression was used to determine the relationship between plasma RIP3 levels and CAD. The correlation between plasma RIP3 and GSS was calculated using multiple linear regression models. Results: Overall, plasma RIP3 levels were significantly higher than serum RIP3 levels. Plasma RIP3 levels in patients with CAD were significantly higher than those in controls. Plasma RIP3 levels were strongly associated with CAD (odds ratio: 6.00, 95% confidence interval 3.04–11.81;P < 0.001). Plasma RIP3 levels increased linearly from controls to patients with SCAD, then patients with UA, and finally to patients with MI. We found a significantly positive correlation between proportion of cases of acute coronary syndrome in subjects and their plasma RIP3 level quartile. Plasma RIP3 levels were also associated with GSS (B 0.027;standard error 0.012;P < 0.05). Conclusions: Plasma RIP3 levels were independently associated with CAD. Plasma RIP3 levels could potentially supplement clinical assessment to screen CAD and determine CAD severity. 展开更多
关键词 RECEPTOR interacting protein kinase-3 CORONARY artery disease NECROPTOSIS Atherosclerosis Acute CORONARY syndrome Biomarker
Coronary angiography in the very old:impact of diabetes on long-term revascularization and mortality 预览
19
作者 Elad Shemesh Barak Zafrir 《老年心脏病学杂志:英文版》 SCIE CAS CSCD 2019年第1期27-32,共6页
Background Diabetes is often associated with coronary artery disease,leading to adverse clinical outcomes.Real-world data is limited regarding the impact of diabetes in very old patients undergoing coronary angiograph... Background Diabetes is often associated with coronary artery disease,leading to adverse clinical outcomes.Real-world data is limited regarding the impact of diabetes in very old patients undergoing coronary angiography on the risk for late or repeated coronary revascularization and mortality.Methods Retrospective analysis of 1,353 consecutive patients>80 years who were admitted to the cardiac unit and further underwent coronary angiography.Subsequent revascularization procedures and all-cause mortality were recorded over a median fbllow-up of 47 months and their relation to diabetic status and presentation with acute coronary syndrome(ACS)was studied.Results Diabetes was present in 31%of the patients undergoing coronary angiography,and was associated with higher rates of obesity,hypertension,hyperlipidemia,chronic kidney disease and female gender.ACS was the presenting diagnosis in 71%of the patients and was associated with worse survival(1-year mortality 20%in ACS vs.6.2%in non-ACS patients,P<0.0001).Increase in long-term mortality rates was seen in diabetic subjects compared to non-diabetic subjects presenting with ACS(log-rank P=0.005),but not in the non-ACS setting(P=0」99).In a multivariable model,additionally adjusting for acuity of presentation,the presence of diabetes was associated with an adjusted hazard ratio of 1.60(95%confidence interval:12-2.28),P=0.011,for the need of late or repeat coronary revascularization and 1.48(1.26-1.74),P<0.0001 for all-cause mortality,during long-term follow-up.Conclusions In very old patients undergoing coronary angiography,presentation with ACS was associated with worse survival.Diabetes was an independent predictor of late or repeated revascularization and long-term mortality. 展开更多
关键词 Cardiac CATHETERIZATION CORONARY artery disease CORONARY REVASCULARIZATION DIABETES MELLITUS MORTALITY Very old age
在线阅读 下载PDF
Asymmetric Dimethylarginine Predicts One-year Recurrent Cardiovascular Events: Potential Biomarker of 'Toxin Syndrome' in Coronary Heart Disease
20
作者 XU Hao CHEN Zhuo +4 位作者 SHANG Qing-hua GAO Zhu-ye YU Chang-an SHI Da-zhuo CHEN Ke-ji 《中国结合医学杂志:英文版》 SCIE CAS CSCD 2019年第5期327-333,共7页
Objective: To examine the prognostic value of serum levels of asymmetric dimethylarginine(ADMA)in patients with stable coronary heart disease(CHD) thus explore a potential biomarker of 'toxin syndrome' in CHD.... Objective: To examine the prognostic value of serum levels of asymmetric dimethylarginine(ADMA)in patients with stable coronary heart disease(CHD) thus explore a potential biomarker of 'toxin syndrome' in CHD.Methods: In this prospective nested case-control study, 36 of 1,503 Chinese patients with stable CHD experienced at least 1 recurrent cardiovascular event(RCE) during 1-year fol ow-up. Serum levels of ADMA at the start of fol ow-up were compared between these 36 cases and 36 controls which matched to cases in terms of gender, age, history of hypertension, and myocardial infarction. Results: Based on the crude model, subjects in the 2 highest ADMA quartiles showed signi?cantly higher risk of developing RCE than those in the lowest ADMA quartile (odds ratio(OR) 4.09, 95%confidence interval(CI) 1.01 to 16.58;OR 6.76, 95% CI 1.57 to 29.07)This association was also observed in the case-mix model(OR 5.51, 95% CI 1.23 to 24.61;OR 7.83, 95% CI 1.68 to 36.41) and multivariable model(OR 6.64,95% CI 1.40 to 31.49;OR 13.14, 95% CI 2.28 to 75.71) after adjusting for confounders. The multivariable model which combined ADMA and high-sensitivity C-reactive protein(hs CRP) showed better predictive power with areas under the receiver operator characteristic curves(0.779) than the model of either ADMA(0.694) or hs CRP(0.636). Conclusion:Serum ADMA level may be a potential biomarker of 'toxin syndrome' in CHD which shows favorable prognostic value in predicting 1-year RCE in patients with stable CHD. [The registration number is Chi CTR-PRNRC-07000012] 展开更多
关键词 asymmetric DIMETHYLARGININE RECURRENT cardiovascular event nested CASE-CONTROL study coronary heart disease TOXIN SYNDROME
上一页 1 2 250 下一页 到第
使用帮助 返回顶部 意见反馈