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Texture Feature Extraction from Thyroid MR Imaging Using High-Order Derived Mean CLBP
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作者 Zhe Liu Cheng-Jian Qiu +3 位作者 Yu-Qing Song Xiao-Hong Liu Juan Wang Victor S.Sheng 《计算机科学技术学报:英文版》 SCIE EI CSCD 2019年第1期35-46,共12页
In the field of medical imaging,the traditional local binary pattern (LBP)and its improved algorithms are often sensitive to noise.Traditional LBPs are solely based on the signal information from local differences,and... In the field of medical imaging,the traditional local binary pattern (LBP)and its improved algorithms are often sensitive to noise.Traditional LBPs are solely based on the signal information from local differences,and the binary quantization method oversimplifies the local texture features while disregarding the imaging information from the concaveconvex regions between the high-order pixels and the neighboring sampling points.Therefore,we propose an improved Derived Mean Complete Local Binary Pattern (DM_CLBP) algorithm based on high-order derivatives.In the DM_CLBP method,the grey value of a single pixel is replaced by the mean grey value of the rectangular area block,and the difference between pixel values in the area is obtained using the second-order differentiation method.Based on the calculation concept of the complete local binary pattern (CLBP)algorithm,the cascade signs and magnitudes of the two components are encoded and recombined in DM_CLBP using a uniform pattern.The results from the experiments showed that the proposed DM_CLBP descriptors achieved a classification accuracy of 94.4%.Compared with LBP and other improved algorithms,the DM_CLBP algorithm presented in this study can effectively differentiate between lesion areas and normal areas in thyroid MR,(magnetic resonance)images and shows the improved accuracy of area classification. 展开更多
关键词 THYROID magnetic resonance imaging (MRI) LOCAL BINARY PATTERN texture feature complete LOCAL BINARY PATTERN (CLBP)
Evolution of permafrost in China during the last 20 ka
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作者 Huijun JIN Xiaoying JIN +8 位作者 Ruixia HE Dongliang LUO Xiaoli CHANG Shaoling WANG Sergey S MARCHENKO Sizhong YANG Chaolu YI Shijie LI Stuart A HARRIS 《中国科学:地球科学英文版》 SCIE EI CAS CSCD 2019年第8期1207-1223,共17页
The formation and evolution of permafrost in China during the last 20 ka were reconstructed on the basis of large amount of paleo-permafrost remains and paleo-periglacial evidence, as well as paleo-glacial landforms, ... The formation and evolution of permafrost in China during the last 20 ka were reconstructed on the basis of large amount of paleo-permafrost remains and paleo-periglacial evidence, as well as paleo-glacial landforms, paleo-flora and paleofauna records. The results indicate that, during the local Last Glacial Maximum(LLGM) or local Last Permafrost Maximum(LLPMax), the extent of permafrost of China reached 5.3×106-5.4×106 km2, or thrice that of today, but permafrost shrank to only0.80×106-0.85×106 km2, or 50% that of present, during the local Holocene Megathermal Period(LHMP), or the local Last Permafrost Minimum(LLPMin). On the basis of the dating of periglacial remains and their distributive features, the extent of permafrost in China was delineated for the two periods of LLGM(LLPMax) and LHMP(LLPMin), and the evolution of permafrost in China was divided into seven periods as follows:(1) LLGM in Late Pleistocene(ca. 20000 to 13000-10800 a BP)with extensive evidence for the presence of intensive ice-wedge expansion for outlining its LLPMax extent;(2) A period of dramatically changing climate during the early Holocene(10800 to 8500-7000 a BP) when permafrost remained relatively stable but with a general trend of shrinking areal extent;(3) The LHMP in the Mid-Holocene(8500-7000 to 4000-3000 a BP)when permafrost degraded intensively and extensively, and shrank to the LLPMin;(4) Neoglaciation during the late Holocene(4000-3000 to 1000 a BP, when permafrost again expanded;(5) Medieval Warming Period(MWP) in the late Holocene(1000-500 a BP) when permafrost was in a relative decline;(6) Little Ice Age(LIA) in the late Holocene(500-100 a BP), when permafrost relatively expanded, and;(7) Recent warming(during the 20 th century), when permafrost continuously degraded and still is degrading. The paleo-climate, geography and paleopermafrost extents and other features were reconstructed for each of these seven periods. 展开更多
关键词 PERMAFROST EVOLUTION Cryogenic wedge structures LOCAL LAST GLACIAL Maximum(LLGM) LOCAL Holocene MEGATHERMAL Period(LHMP) China
Local Two Sessions, Local Issues
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作者 Yuan Yuan 《北京周报:英文版》 2019年第5期30-31,共2页
Provincial-level regions restart after a fruitful 2018East China’s Jiangsu Province reported on January 14 that its GDP reached more than 9.2 trillion yuan ($1.36 trillion) in2018, becoming the first Chinese mainland... Provincial-level regions restart after a fruitful 2018East China’s Jiangsu Province reported on January 14 that its GDP reached more than 9.2 trillion yuan ($1.36 trillion) in2018, becoming the first Chinese mainland province to officially announce that its economic aggregate has topped the 9-trillion-yuan hal mark. Jiangsu’s economy has surpassed that of Australia, the 13th largest in the world.Governor Wu Zhenglong unveiled the fi gure at the annual session of the Jiangsu Provincial People’s Congress, the provincial legislature. 展开更多
关键词 GDP In LOCAL TWO SESSIONS LOCAL ISSUES
局部麻醉药物在儿童口腔诊疗中的应用 预览
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作者 韩欣欣 汪璐璐 +2 位作者 王子瑞 赵辛 王小竞 《中华口腔医学研究杂志(电子版)》 CAS 2019年第1期51-55,共5页
无痛及舒适化诊疗等技术的提出,使局部麻醉药物在临床的应用更加广泛,尤其是在儿童口腔诊疗中的应用。儿童生长发育与成人存在较大的生理差异,在疼痛控制和局部麻醉药物的应用与成人不同。本文就国内外学者关于各类局部麻醉药物在儿童... 无痛及舒适化诊疗等技术的提出,使局部麻醉药物在临床的应用更加广泛,尤其是在儿童口腔诊疗中的应用。儿童生长发育与成人存在较大的生理差异,在疼痛控制和局部麻醉药物的应用与成人不同。本文就国内外学者关于各类局部麻醉药物在儿童口腔局部麻醉应用中的系统毒性、最大推荐剂量以及舒适化麻醉方法进行综述,旨在为儿童口腔医生临床应用局部麻醉药物提供帮助。 展开更多
关键词 儿童口腔医学 麻醉药 局部 最大耐受剂量 患者舒适 局部麻醉系统毒性
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我国地方性公共图书馆法规中有关地方文献条款内容分析与启示 预览
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作者 陈汝模 《图书馆理论与实践》 CSSCI 2019年第4期28-33,共6页
地方性公共图书馆法是保障地方文献工作有序运行的重要法律支撑,指引着地方文献事业走向体系化、规范化、法制化。文章对我国现行的19部地方性公共图书馆法规进行了梳理,分析其中有关地方文献条款的规定,并将分析结论运用于地方文献保... 地方性公共图书馆法是保障地方文献工作有序运行的重要法律支撑,指引着地方文献事业走向体系化、规范化、法制化。文章对我国现行的19部地方性公共图书馆法规进行了梳理,分析其中有关地方文献条款的规定,并将分析结论运用于地方文献保护整理与开发之中,以期为地方文献的收集、整理、保存、开发、利用及延长文献生命周期价值链等提供经验及借鉴。 展开更多
关键词 公共图书馆法规 地方性 地方文献 公共图书馆
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晚清官绅政治与帝国崩解--以重庆团练与地方权力结构为视角
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作者 谯珊 《中华文化论坛》 北大核心 2019年第1期35-46,156共13页
官绅政治是清代地方政治的基本架构,允许绅权存在是清代社会的常态,而非异态。咸同时期,地方士绅因举办团练,绅权或有扩张,然"绅权扩张"与"帝国崩溃"并不构成因果关联。重庆在咸同团练举办后,地方权力结构呈现出延... 官绅政治是清代地方政治的基本架构,允许绅权存在是清代社会的常态,而非异态。咸同时期,地方士绅因举办团练,绅权或有扩张,然"绅权扩张"与"帝国崩溃"并不构成因果关联。重庆在咸同团练举办后,地方权力结构呈现出延续守旧的特点,官权仍然控驭绅权。但19世纪中叶以后,重庆的官绅政治架构在外国进入导致的各类"新危机"中渐显裂隙,终在20世纪初士绅退出的过程中轰然解体,致使地方秩序失控,为辛亥革命在重庆爆发提供了土壤。清帝国崩溃与地方官绅政治体系失控同步,非绅权扩张所致。 展开更多
关键词 地方 官绅政治 团练 帝国崩解 重庆
Spatial-temporal variations of natural suitability of human settlement environment in the Three Gorges Reservoir Area A case study in Fengjie County,China
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作者 Jieqiong LUO Tinggang ZHOU +1 位作者 Peijun DU Zhigang XU 《地球科学前沿:英文版》 SCIE CAS CSCD 2019年第1期1-17,共17页
With rapid environmental degeneration and socio-economie development,the human settlement environment (HSE)has experienced dramatic changes and attracted attention from different communities.Consequently,the spatial-t... With rapid environmental degeneration and socio-economie development,the human settlement environment (HSE)has experienced dramatic changes and attracted attention from different communities.Consequently,the spatial-temporal evaluation of natural suitability of the human settlement environment (NSHSE)has become essential for understanding the patterns and dynamics of HSE,and for coordinating sustainable development among regional populations,resources,and environments.This study aims to explore the spatialtemporal evolution of NSHSE patterns in 1997,2005,and 2009 in Fengjie County near the Three Gorges Reservoir Area (TGRA).A spatially weighted NSHSE model was established by integrating multi-source data (e.g.,census data,meteorological data,remote sensing images,DEM data,and GIS data)into one framework,where the Ordinary Least Squares (OLS)linear regression model was applied to calculate the weights of indices in the NSHSE model.Results show that the trend of natural suitability has been first downward and then upward, which is evidenced by the disparity of NSHSE existing in the south,north,and central areas of Fengjie County. Results also reveal clustered NSHSE patterns for all 30 townships.Meanwhile,NSHSE has significant influence on population distribution,and 71.49% of the total population is living in moderate and high suitable districts. 展开更多
关键词 NATURAL SUITABILITY of human SETTLEMENT ENVIRONMENT ordinary least SQUARES model global and local spatial AUTOCORRELATION analyses Three Gorges Reservoir Area (TGRA) Fengjie Cotmty
Local scour around two side-by-side cylindrical bridge piers under ice-covered conditions 预览
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作者 Mohammad reza Namaee Jueyi Sui 《国际泥沙研究:英文版》 SCIE 2019年第4期355-367,共13页
In the current study, 108 flume experiments with non-uniform, cohesionless sediments have been done to investigate the local scour process around four pairs of side-by-side bridge piers under both open channel and ice... In the current study, 108 flume experiments with non-uniform, cohesionless sediments have been done to investigate the local scour process around four pairs of side-by-side bridge piers under both open channel and ice-covered flow conditions. Similar to local scour around bridge piers under open channel conditions and a single bridge pier, it was observed in the experiments that the maximum scour depth always occurred at the upstream face of the pier under ice-covered conditions. Further, the smaller the pier size and the greater the spacing distance between the bridge piers, the weaker the horseshoe vortices around the bridge piers, and, thus, the shallower the scour holes around them. Finally, empirical equations were developed to estimate the maximum scour depth around two side-by-side bridge piers under both open channel and ice-covered flow conditions. 展开更多
关键词 Bridge PIER Local SCOUR Maximum SCOUR DEPTH NON-UNIFORM sediment ROUGHNESS of COVER SCOUR pattern
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颅底原发性淋巴瘤的诊断和治疗 预览
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作者 孟肖利 周生余 +1 位作者 张玲君 万经海 《中国微侵袭神经外科杂志》 CAS 2019年第1期17-20,共4页
目的探讨颅底原发性淋巴瘤的临床特点、治疗和预后。方法回顾性分析8例颅底原发性淋巴瘤病人的临床资料,肿瘤常见发生部位包括海绵窦、蝶岩斜区和颅中底-颞下窝-翼腭窝区;受累海绵窦段颈内动脉被肿瘤包裹,而少有移位或狭窄是主要的影像... 目的探讨颅底原发性淋巴瘤的临床特点、治疗和预后。方法回顾性分析8例颅底原发性淋巴瘤病人的临床资料,肿瘤常见发生部位包括海绵窦、蝶岩斜区和颅中底-颞下窝-翼腭窝区;受累海绵窦段颈内动脉被肿瘤包裹,而少有移位或狭窄是主要的影像学特点。8例病人均经鼻蝶或经唇下-上颌窦入路完成活检。结果病理类型均为非霍奇金淋巴瘤,其中弥漫大B细胞淋巴瘤7例,大细胞间变性淋巴瘤1例;术后行化疗和局部放疗。随访8例,时间6~112个月,病人中位生存时间52个月;完全缓解率为62.5%。结论颅底原发性淋巴瘤是一类临床罕见的颅底肿瘤,病理类型以弥漫大B细胞淋巴瘤为主;多为中老年发病,常累及海绵窦、蝶岩斜区、颅中底-颞下窝-翼腭窝区。手术活检、化疗和局部放疗联合的多学科综合治疗是目前主要的治疗策略。 展开更多
关键词 淋巴瘤 原发性 颅底 淋巴瘤 非霍奇金 活组织检查 化疗 放疗 局部
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The Conversion Relationship between the Local Earthquake Magnitude and Surface Wave Magnitude in the Inner Mongolia Digital Seismic Network 预览
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作者 LIU Fang SU Riya +2 位作者 XU Xiquan LI Hui NA Re 《中国地震研究:英文版》 CSCD 2019年第1期86-96,共11页
Using 116 earthquakes over ML3. 8 in the Inner Mongolia region from 2008 to 2015, the local earthquake magnitude ML and surface wave magnitude MS are remeasured. Based on norm linear regression (SR1 and SR2) and norm ... Using 116 earthquakes over ML3. 8 in the Inner Mongolia region from 2008 to 2015, the local earthquake magnitude ML and surface wave magnitude MS are remeasured. Based on norm linear regression (SR1 and SR2) and norm (OR) orthogonal regression method, we established the conversion relationship between ML and MS . The results were tested with Gaussian disturbance. The result shows that the orthogonal regression method (OR) result has the best fitting curve, and the conversion relation is MS = 0. 96 ML - 0. 10. The difference between our result and Guo Lücan's (MS = 1. 13 ML -1. 08) may be caused by regional tectonic characteristics. MS Inner Mongolia value is significantly higher than the MS empirical value, with an average difference of 0. 23, the difference distribution of empirical relation and the rectified relation is in the range of 0. 2-0. 3. 展开更多
关键词 Local EARTHQUAKE MAGNITUDE ML Surface wave MAGNITUDE MS GAUSS PERTURBATION MAGNITUDE CONVERSION
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局部高强度降雨的地质灾害特征分析 预览
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作者 马秀梅 刘晓燕 +1 位作者 代青措 马琼 《灾害学》 CSCD 北大核心 2019年第1期38-41,共4页
传统地质灾害特征分析方法,以地面综合调查为主,忽视局部高强度降雨条件这一主观因素,使得地质灾害特征分析结果存在较高的片面性。该文提出基于局部高强度降雨的地质灾害特征分析方法,根据降雨强度、灾害持续时间和平均降雨量等指标设... 传统地质灾害特征分析方法,以地面综合调查为主,忽视局部高强度降雨条件这一主观因素,使得地质灾害特征分析结果存在较高的片面性。该文提出基于局部高强度降雨的地质灾害特征分析方法,根据降雨强度、灾害持续时间和平均降雨量等指标设立临界组合判别运算雨量阈值,按照雨量阈值判断地质灾害类型,并结合预警判据图分析局部高强降雨的地质灾害分布特征。实验结果表明,所提方法可全面分析出实验地区地质灾害具有滞后性、群发性和同时性特征。 展开更多
关键词 地质灾害 灾害特征 高强度降雨 局部 雨量阈值 预警判据图 临界降雨量
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Cloud detection from visual band of satellite image based on variance of fractal dimension 预览
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作者 TIAN Pingfang GUANG Qiang LIU Xing 《系统工程与电子技术:英文版》 SCIE EI CSCD 2019年第3期485-491,共7页
Cover ratio of cloud is a very important factor which affects the quality of a satellite image, therefore cloud detection from satellite images is a necessary step in assessing the image quality. The study on cloud de... Cover ratio of cloud is a very important factor which affects the quality of a satellite image, therefore cloud detection from satellite images is a necessary step in assessing the image quality. The study on cloud detection from the visual band of a satellite image is developed. Firstly, we consider the differences between the cloud and ground including high grey level, good continuity of grey level, area of cloud region, and the variance of local fractal dimension (VLFD) of the cloud region. A single cloud region detection method is proposed. Secondly, by introducing a reference satellite image and by comparing the variance in the dimensions corresponding to the reference and the tested images, a method that detects multiple cloud regions and determines whether or not the cloud exists in an image is described. By using several Ikonos images, the performance of the proposed method is demonstrated. 展开更多
关键词 CLOUD detection VISUAL IMAGE SATELLITE IMAGE variance of local FRACTAL dimension (VLFD)
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地方红色文化在高校思想政治教育的运用研究 预览
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作者 杜石清 《陕西工业职业技术学院学报》 2019年第1期43-45,共3页
地方红色文化是地方特有的宝贵财富,也是高校开展大学生思想政治教育的重要组成部分.通过实地参观、耳濡目染的方式加强大学生的理想信念教育和爱国主义教育,进一步拓宽思想政治教育的育人功能。文章围绕思想政治教育教育融入地方红色... 地方红色文化是地方特有的宝贵财富,也是高校开展大学生思想政治教育的重要组成部分.通过实地参观、耳濡目染的方式加强大学生的理想信念教育和爱国主义教育,进一步拓宽思想政治教育的育人功能。文章围绕思想政治教育教育融入地方红色文化的必要性,分析了当前地方红色文化融入高校思想政治教育现状,提出了地方红色文化融入高校思想政治教育的对策。 展开更多
关键词 地方 红色文化 高校 思想政治教育
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A general framework for frequentist model averaging In Celebration of Professor Lincheng Zhao’s 75th Birthday
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作者 Priyam Mitra Heng Lian +2 位作者 Ritwik Mitra Hua Liang Min-ge Xie 《中国科学:数学英文版》 SCIE CSCD 2019年第2期205-226,共22页
Model selection strategies have been routinely employed to determine a model for data analysis in statistics, and further study and inference then often proceed as though the selected model were the true model that we... Model selection strategies have been routinely employed to determine a model for data analysis in statistics, and further study and inference then often proceed as though the selected model were the true model that were known a priori. Model averaging approaches, on the other hand, try to combine estimators for a set of candidate models. Specifically, instead of deciding which model is the ’right’ one, a model averaging approach suggests to fit a set of candidate models and average over the estimators using data adaptive weights.In this paper we establish a general frequentist model averaging framework that does not set any restrictions on the set of candidate models. It broaden, the scope of the existing methodologies under the frequentist model averaging development. Assuming the data is from an unknown model, we derive the model averaging estimator and study its limiting distributions and related predictions while taking possible modeling biases into account.We propose a set of optimal weights to combine the individual estimators so that the expected mean squared error of the average estimator is minimized. Simulation studies are conducted to compare the performance of the estimator with that of the existing methods. The results show the benefits of the proposed approach over traditional model selection approaches as well as existing model averaging methods. 展开更多
关键词 ASYMPTOTIC distribution BIAS variance trade-off local mis-specification model AVERAGING ESTIMATORS optimal weight selection
Predicting systemic spread in early colorectal cancer: Can we do better? 预览
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作者 Scarlet Fiona Brockmoeller Nicholas Paul West 《世界胃肠病学杂志:英文版》 SCIE CAS 2019年第23期2887-2897,共11页
Through the implementation of national bowel cancer screening programmes we have seen a three-fold increase in early pT1 colorectal cancers, but how these lesions should be managed is currently unclear. Local excision... Through the implementation of national bowel cancer screening programmes we have seen a three-fold increase in early pT1 colorectal cancers, but how these lesions should be managed is currently unclear. Local excision can be an attractive option, especially for fragile patients with multiple comorbidities, but it is only safe from an oncological point of view in the absence of lymph node metastasis. Patient risk stratification through careful analysis of histopathological features in local excision or polypectomy specimens should be performed according to national guidelines to avoid under-or over-treatment. Currently national guidelines vary in their recommendations as to which factors should be routinely reported and there is no established multivariate risk stratification model to determine which patients should be offered major resectional surgery.Conventional histopathological parameters such as tumour grading or lymphovascular invasion have been shown to be predictive of lymph node metastasis in a number of studies but the inter-and intra-observer variation in reporting is high. Newer parameters including tumour budding and poorly differentiated clusters have been shown to have great potential, but again some improvement in the inter-observer variation is required. With the implementation of digital pathology into clinical practice, quantitative parameters like depth/area of submucosal invasion and proportion of stroma can be routinely assessed. In this review we present the various histopathological risk factors for predicting systemic spread in pT1 colorectal cancer and introduce potential novel quantitative variables and multivariable risk models that could be used to better define the optimal treatment of this increasingly common disease. 展开更多
关键词 Early colorectal CANCER Bowel CANCER screening Local RESECTION Major RESECTION Morphological RISK factors Conventional HISTOPATHOLOGY PARAMETERS Novel HISTOPATHOLOGY PARAMETERS RISK STRATIFICATION models Digital pathology
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A Memetic Algorithm With Competition for the Capacitated Green Vehicle Routing Problem 预览
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作者 Ling Wang Jiawen Lu 《自动化学报:英文版》 CSCD 2019年第2期516-526,共11页
In this paper, a memetic algorithm with competition(MAC) is proposed to solve the capacitated green vehicle routing problem(CGVRP). Firstly, the permutation array called traveling salesman problem(TSP) route is used t... In this paper, a memetic algorithm with competition(MAC) is proposed to solve the capacitated green vehicle routing problem(CGVRP). Firstly, the permutation array called traveling salesman problem(TSP) route is used to encode the solution, and an effective decoding method to construct the CGVRP route is presented accordingly. Secondly, the k-nearest neighbor(k NN) based initialization is presented to take use of the location information of the customers. Thirdly, according to the characteristics of the CGVRP, the search operators in the variable neighborhood search(VNS) framework and the simulated annealing(SA) strategy are executed on the TSP route for all solutions. Moreover, the customer adjustment operator and the alternative fuel station(AFS) adjustment operator on the CGVRP route are executed for the elite solutions after competition. In addition, the crossover operator is employed to share information among different solutions. The effect of parameter setting is investigated using the Taguchi method of design-ofexperiment to suggest suitable values. Via numerical tests, it demonstrates the effectiveness of both the competitive search and the decoding method. Moreover, extensive comparative results show that the proposed algorithm is more effective and efficient than the existing methods in solving the CGVRP. 展开更多
关键词 Capacitated green VEHICLE ROUTING problem(CGVRP) COMPETITION k-nearest neighbor(kNN) local INTENSIFICATION memetic algorithm
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FERTILE LAND
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《北京周报:英文版》 2019年第37期3-11,共9页
An aerial photo taken on September 4 shows villagers waiting in lines to sell tomatoes to local vegetable processing factories in Sandaoqiao 丁own in the Hetao Irrigation Area in north Ghina’s Inner Mongolia Autonomo... An aerial photo taken on September 4 shows villagers waiting in lines to sell tomatoes to local vegetable processing factories in Sandaoqiao 丁own in the Hetao Irrigation Area in north Ghina’s Inner Mongolia Autonomous Region. The International Commission on Irrigation and Drainage added the area to its World Heritage Irrigation Structures list that day. 展开更多
关键词 FERTILE LAND factories LOCAL VEGETABLE
LKLR: A Local Tangent Space-Alignment Kernel Least-Squares Regression Algorithm
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作者 Chao Tan Genlin Ji 《清华大学学报自然科学版(英文版)》 EI CAS CSCD 2019年第4期389-399,共11页
In the fields of machine learning and data mining, label learning is a nascent area of research, and within this paradigm, there is much room for improving multi-label manifold learning algorithms for high-dimensional... In the fields of machine learning and data mining, label learning is a nascent area of research, and within this paradigm, there is much room for improving multi-label manifold learning algorithms for high-dimensional data. Thus far, researchers have experimented with mapping relationships from the feature space to the traditional logical label space(using neighbors in the label space, for example, to predict logical label vectors from the feature space’s manifold structure). Here we combine the feature manifold’s and label space’s local topological structures to reconstruct the label manifold. To achieve this, we use a nonlinear manifold learning algorithm to transform the local topological structure from the feature space to the label space. Our algorithm adopts a regularized leastsquares kernel method to realize the reconstruction process, employing an optimization function to find the best solution. Extensive experiments show that our algorithm significantly improves multi-label manifold learning in terms of learning accuracy and time complexity. 展开更多
关键词 MULTI-LABEL MANIFOLD learning local topological structure REGULARIZED least SQUARES KERNEL method
Altered Local Field Potential Relationship Between the Parafascicular Thalamic Nucleus and Dorsal Striatum in Hemiparkinsonian Rats
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作者 Haiyan Zhang Jing Yang +9 位作者 Xuenan Wang Xiaomeng Yao Hongyu Han Yunfeng Gao Hongli Chang Tianyu Xiang Shuang Sun Yanan Wang Xiusong Wang Min Wang 《神经科学通报:英文版》 SCIE CAS CSCD 2019年第2期315-324,共10页
The thalamostriatal pathway is implicated in Parkinson’s disease(PD);however, PD-related changes in the relationship between oscillatory activity in the centromedian-parafascicular complex(CM/Pf, or the Pf in rodents... The thalamostriatal pathway is implicated in Parkinson’s disease(PD);however, PD-related changes in the relationship between oscillatory activity in the centromedian-parafascicular complex(CM/Pf, or the Pf in rodents) and the dorsal striatum(DS) remain unclear.Therefore, we simultaneously recorded local field potentials(LFPs) in both the Pf and DS of hemiparkinsonian and control rats during epochs of rest or treadmill walking. The dopamine-lesioned rats showed increased LFP power in the beta band(12 Hz–35 Hz) in the Pf and DS during both epochs, but decreased LFP power in the delta(0.5 Hz–3 Hz) band in the Pf during rest epochs and in the DS during both epochs, compared to control rats. In addition,exaggerated low gamma(35 Hz–70 Hz) oscillations after dopamine loss were restricted to the Pf regardless of the behavioral state. Furthermore, enhanced synchronization of LFP oscillations was found between the Pf and DS after the dopamine lesion. Significant increases occurred in the mean coherence in both theta(3 Hz–7 Hz) and beta bands,and a significant increase was also noted in the phase coherence in the beta band between the Pf and DS during rest epochs. During the treadmill walking epochs, significant increases were found in both the alpha(7 Hz–12 Hz)and beta bands for two coherence measures. Collectively,dramatic changes in the relative LFP power and coherence in the thalamostriatal pathway may underlie the dysfunction of the basal ganglia-thalamocortical network circuits in PD, contributing to some of the motor and non-motor symptoms of the disease. 展开更多
关键词 Parkinson’s disease Parafascicular THALAMIC NUCLEUS DORSAL STRIATUM Local field potential Synchronization
原发性甲状腺功能亢进症并甲状腺癌的临床分析
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作者 汪丽平 蔡成福 刘存山 《中国基层医药》 CAS 2019年第14期1686-1688,共3页
目的分析原发性甲状腺功能亢进症(甲亢)并甲状腺癌的临床病理特征.方法回顾性分析2010年1月至2018年7月在厦门大学附属第一医院接受甲状腺切除术的甲状腺癌患者418例的临床病理资料,依据甲状腺功能分为两组,A组(n=39)甲亢,B组(n=379)甲... 目的分析原发性甲状腺功能亢进症(甲亢)并甲状腺癌的临床病理特征.方法回顾性分析2010年1月至2018年7月在厦门大学附属第一医院接受甲状腺切除术的甲状腺癌患者418例的临床病理资料,依据甲状腺功能分为两组,A组(n=39)甲亢,B组(n=379)甲状腺功能正常.分析并比较两组的临床病理特征.结果两组年龄、性别、肿瘤分期、肿瘤直径差异均无统计学意义(均P>0.05);A组淋巴结转移率为17.9%(7/39),高于B组的6.1%(23/379)(χ2=5.814,P=0.016).A组术后暂时性甲状旁腺功能减退发生率为28.2%(11/39),高于B组的13.2%(50/379)(χ2=6.394,P<0.05);A组局部复发率为5.1%(2/39),高于B组的2.4%(9/379),但差异无统计学意义(χ2=0.248,P=0.619);A组5年无病生存率为84.6%(33/39),低于B组的95.8%(363/379)(χ2=6.740,P<0.05).结论甲亢合并甲状腺癌具有较高侵袭性行为,应采取积极的治疗方法. 展开更多
关键词 甲状腺功能亢进症 甲状腺肿瘤 甲状腺功能试验 甲状腺功能减退症 肿瘤分期 淋巴转移 肿瘤复发 局部 存活率 病理学 临床
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