期刊文献+
共找到129,509篇文章
< 1 2 250 >
每页显示 20 50 100
Outgrowth endothelial cells form a functional cerebral barrier and restore its integrity after damage 预览
1
作者 Rais Reskiawan Abdulkadir Mansour Alwjwaj +2 位作者 Othman Ahmad Othman Kamini Rakkar Ulvi Bayraktutan 《中国神经再生研究:英文版》 SCIE CAS CSCD 2020年第6期1071-1078,共8页
Breakdown of blood-brain barrier,formed mainly by brain microvascular endothelial cells(BMECs),represents the major cause of mortality during early phases of ischemic strokes.Hence,discovery of novel agents that can e... Breakdown of blood-brain barrier,formed mainly by brain microvascular endothelial cells(BMECs),represents the major cause of mortality during early phases of ischemic strokes.Hence,discovery of novel agents that can effectively replace dead or dying endothelial cells to restore blood-brain barrier integrity is of paramount importance in stroke medicine.Although endothelial progenitor cells(EPCs)represent one such agents,their rarity in peripheral blood severely limits their adequate isolation and therapeutic use for acute ischemic stroke which necessitate their ex vivo expansion and generate early EPCs and outgrowth endothelial cells(OECs)as a result.Functional analyses of these cells,in the present study,demonstrated that only OECs endocytosed DiI-labelled acetylated low-density lipoprotein and formed tubules on matrigel,prominent endothelial cell and angiogenesis markers,respectively.Further analyses by flow cytometry demonstrated that OECs expressed specific markers for sternness(CD34),immaturity(CD133)and endothelial cells(CD31)but not for hematopoietic cells(CD45).Like BMECs,OECs established an equally tight in vitro model of human BBB with astrocytes and pericytes,suggesting their capacity to form tight junctions.Ischemic injury mimicked by concurrent deprivation of oxygen and glucose(4 hours)or deprivation of oxygen and glucose followed by reperfusion(20 hours)affected both barrier integrity and function in a similar fashion as evidenced by decreases in transendothelial electrical resistance and increases in paracellular flux,respectively.Wound scratch assays comparing the vasculoreparative capacity of cells revealed that,compared to BMECs,OECs possessed a greater proliferative and directional migratory capacity.In a triple culture model of BBB established with astrocytes,pericytes and BMEC,exogenous addition of OECs effectively repaired the damage induced on endothelial layer in serum-free conditions.Taken together,these data demonstrate that OECs may effectively home to the site of vascular injury and re 展开更多
关键词 cell-based therapy endothelial progenitor cells ENDOTHELIUM ischemic stroke NEURODEGENERATION novel therapeutics outgrowth endothelial cells regenerative medicine stem cells translational medicine
在线阅读 下载PDF
Identification of protein targets for the antidepressant effects of Kai-Xin-San in Chinese medicine using isobaric tags for relative and absolute quantitation 预览
2
作者 Xian-Zhe Dong Dong-Xiao Wang +3 位作者 Tian-Yi Zhang Xu Liu Ping Liu Yuan Hu 《中国神经再生研究:英文版》 SCIE CAS CSCD 2020年第2期302-310,共9页
Kai-Xin-San consists of Ginseng Radix, Polygalae Radix, Acori Tatarinowii Rhizoma, and Poria at a ratio of 3:3:2:2. Kai-Xin-San has been widely used for the treatment of emotional disorders in China. However, no studi... Kai-Xin-San consists of Ginseng Radix, Polygalae Radix, Acori Tatarinowii Rhizoma, and Poria at a ratio of 3:3:2:2. Kai-Xin-San has been widely used for the treatment of emotional disorders in China. However, no studies have identified the key proteins implicated in response to Kai-Xin-San treatment. In this study, rat models of chronic mild stress were established using different stress methods over 28 days. After 14 days of stress stimulation, rats received daily intragastric administrations of 600 mg/kg Kai-Xin-San. The sucrose preference test was used to determine depression-like behavior in rats, while isobaric tags were used for relative and absolute quantitation-based proteomics to identify altered proteins following Kai-Xin-San treatment. Kai-Xin-San treatment for 2 weeks noticeably improved depression-like behaviors in rats with chronic mild stress. We identified 33 differentially expressed proteins: 7 were upregulated and 26 were downregulated. Functional analysis showed that these differentially expressed proteins participate in synaptic plasticity, neurodevelopment, and neurogenesis. Our results indicate that Kai-Xin-San has an important role in regulating the key node proteins in the synaptic signaling network, and are helpful to better understand the mechanism of the antidepressive effects of Kai-Xin-San and to provide objective theoretical support for its clinical application. The study was approved by the Ethics Committee for Animal Research from the Chinese PLA General Hospital(approval No. X5-2016-07) on March 5, 2016. 展开更多
关键词 BRAIN-DERIVED neurotrophic factor signal pathway depression ISOBARIC tags for RELATIVE and absolute quantitation Kai-Xin-San neurogenesis protein network proteomics analysis synaptic plasticity traditional Chinese medicine
在线阅读 下载PDF
Stroke gets in your eyes:stroke-induced retinal ischemia and the potential of stem cell therapy 预览
3
作者 Chase Kingsbury Matt Heyck +2 位作者 Brooke Bonsack Jea-Young Lee Cesar V.Borlongan 《中国神经再生研究:英文版》 SCIE CAS CSCD 2020年第6期1014-1018,共5页
Stroke persists as a global health and economic crisis,yet only two interventions to reduce stroke-induced brain injury exist.In the clinic,many patients who experience an ischemic stroke often further suffer from ret... Stroke persists as a global health and economic crisis,yet only two interventions to reduce stroke-induced brain injury exist.In the clinic,many patients who experience an ischemic stroke often further suffer from retinal ischemia,which can inhibit their ability to make a functional recovery and may diminish their overall quality of life.Despite this,no treatments for retinal ischemia have been developed.In both cases,ischemia-induced mitochondrial dysfunction initiates a cell loss cascade and inhibits endogenous brain repair.Stem cells have the ability to transfer healthy and functional mitochondria not only ischemic neurons,but also to similarly endangered retinal cells,replacing their defective mitochondria and thereby reducing cell death.In this review,we encapsulate and assess the relationship between cerebral and retinal ischemia,recent preclinical advancements made using in vitro and in vivo retinal ischemia models,the role of mitochondrial dysfunction in retinal ischemia pathology,and the therapeutic potential of stem cell-mediated mitochondrial transfer.Furthermore,we discuss the pitfalls in classic rodent functional assessments and the potential advantages of laser Doppler as a metric of stroke progression.The studies evaluated in this review highlight stem cell-derived mitochondrial transfer as a novel therapeutic approach to both retinal ischemia and stroke.Furthermore,we posit the immense correlation between cerebral and retinal ischemia as an underserved area of study,warranting exploration with the aim of these treating injuries together. 展开更多
关键词 laser Doppler MCAO mesenchymal stem cells mitochondrial network mitochondrial transfer ophthalmic artery optic nerve oxygen-glucose deprivation regenerative medicine retinal ganglion cells visual impairment
在线阅读 下载PDF
Therapeutic potential of natural compounds from Chinese medicine in acute and subacute phases of ischemic stroke 预览
4
作者 Bei Zhang Kathryn ESaatman Lei Chen 《中国神经再生研究:英文版》 SCIE CAS CSCD 2020年第3期416-424,共9页
Stroke is one of the leading causes of death and disability in adults worldwide,resulting in huge social and financial burdens.Extracts from herbs,especially those used in Chinese medicine,have emerged as new pharmace... Stroke is one of the leading causes of death and disability in adults worldwide,resulting in huge social and financial burdens.Extracts from herbs,especially those used in Chinese medicine,have emerged as new pharmaceuticals for stroke treatment.Here we review the evidence from preclinical studies investigating neuroprotective properties of Chinese medicinal compounds through their application in acute and subacute phases of ischemic stroke,and highlight potential mechanisms underlying their therapeutic effects.It is noteworthy that many herbal compounds have been shown to target multiple mechanisms and in combinations may exert synergistic effects on signaling pathways,thereby attenuating multiple aspects of ischemic pathology.We conclude the paper with a general discussion of the prospects for novel natural compound-based regimens against stroke. 展开更多
关键词 cell death HERBAL compound immune response ISCHEMIC stroke therapy NEUROPLASTICITY NEUROPROTECTION oxidative damage traditional Chinese medicine
在线阅读 下载PDF
Retrospective analysis of eFAST ultrasounds performed on trauma activations at an academic level-1 trauma center 预览
5
作者 Samantha Shwe Lauren Witchey +3 位作者 Shadi Lahham Ethan Kunstadt Inna Shniter John C.Fox 《世界急诊医学杂志(英文)》 CAS CSCD 2020年第1期12-17,共6页
BACKGROUND:Point-of-care ultrasound(POCUS)has become increasingly integrated into the practice of emergency medicine.A common application is the extended focused assessment with sonography in trauma(eFAST)exam.The Ame... BACKGROUND:Point-of-care ultrasound(POCUS)has become increasingly integrated into the practice of emergency medicine.A common application is the extended focused assessment with sonography in trauma(eFAST)exam.The American College of Emergency Physicians has guidelines regarding the scope of ultrasound in the emergency department and the appropriate documentation.The objective of this study was to conduct a review of performed,documented and billed eFAST ultrasounds on trauma activation patients.METHODS:This was a retrospective review of all trauma activation patients during a 10-month period at an academic level-one trauma center.A list comparing all trauma activations was crossreferenced with a list of all billed eFAST scans.Medical records were reviewed to determine whether an eFAST was indicated,performed,and appropriately documented.RESULTS:We found that 1,507 of 1,597 trauma patients had indications for eFAST,but 396(27%)of these patients did not have a billed eFAST.Of these 396 patients,87(22%)had documentation in the provider note that an eFAST was performed but there was no separate procedure note.The remaining 309(78%)did not have any documentation of the eFAST in the patient’s chart although an eFAST was recorded and reviewed during ultrasound quality assurance.CONCLUSION:A significant proportion of trauma patients had eFAST exams performed but were not documented or billed.Lack of documentation was multifactorial.Emergency ultrasound programs require appropriate reimbursement to support training,credentialing,equipment,quality assurance,and device maintenance.Our study demonstrates a significant absence of adequate documentation leading to potential revenue loss for an emergency ultrasound program. 展开更多
关键词 Point-of-care ultrasound Emergency medicine Focused assessment withsonography in trauma Trauma activation Blunt trauma
在线阅读 免费下载
Medicine has always been "Modern" and “Scientific” from ancient times to the present day
6
作者 Mikhail Teppone 《结合医学学报:英文版》 CAS CSCD 2019年第4期229-237,共9页
Throughout human history, doctors and healers have gathered and refined the knowledge inherited from the previous generations. Different methods of effective therapy have been designed during various historical period... Throughout human history, doctors and healers have gathered and refined the knowledge inherited from the previous generations. Different methods of effective therapy have been designed during various historical periods;when each was developed, it was considered "modern scientific medicine" for their time. Mankind has gone through natural and social disasters and survived;hence, history has proved there was no time when medical knowledge was eironeous or ineffective. Classic medicine has grown to be divided into narrow, specialized branches, causing it to lose its holistic approach and general view on health, sickness and therapeutic methods. Many of traditional medicine's effective methods have been forgotten and removed from the mainstream medicine. It would be good for modern medical education to incorporate the general knowledge of historically effective therapeutic modalities and study practical cases. Medical students should be taught how to choose a "good method" or "good medicine" independent of when that method or remedy was discovered. However, he has to keep in mind the primary goal of medicine:"I will use treatment to help the sick according to my ability and judgment..."(from Hippocratic Oath). 展开更多
关键词 INTEGRATIVE MEDICINE Alternative MEDICINE Traditional Chinese MEDICINE HOMEOPATHY Cellular therapy
The necessity for integrating traditional, complementary, and alternative medicine into medical education curricula in Iran
7
作者 Mohammad Hossein Ayati Ata Pourabbasi +4 位作者 Nazli Namazi Arman Zargaran Zahra Kheiry Amir Hooman Kazemi Bagher Larijani 《结合医学学报:英文版》 CAS CSCD 2019年第4期296-301,共6页
Background: The use of traditional and complementary medicine (T&CM) is increasing in both developed and developing countries. The school of Persian medicine (PM) in Iran is a comprehensive medical school that is ... Background: The use of traditional and complementary medicine (T&CM) is increasing in both developed and developing countries. The school of Persian medicine (PM) in Iran is a comprehensive medical school that is rich in history and has its own special principles, elements, philosophy, and diagnostic and treatment options. Many complementary therapy modalities are also popular and in demand among patients and physicians. The aim of this paper is to provide logic for the policymakers in Iranian medical education to make changes in medical education curricula, particularly on integrating T&CM. Methods: We reviewed the global experience in teaching T&CM to medical students, and highlighting the strengths of PM, described why it is necessary to integrate T&CM into general medicine curricula in Iran. Results: PM is a traditional system of medicine that dates back about 7000 years. Although there are few studies about the safety and effectiveness of PM, research into it has recently been accelerated. There is a suitable opportunity for integrating T&CM with conventional medicine. Physicians should be familiar with T&CM to avoid any contraindications, interactions, and unwanted effects. Conclusion: Traditional medicine is part of Iran's heritage and. thus, needs special attention. Familiarization of physicians with T&CM can help them choose the best treatment options for their patients. To integrate T&CM into the medical education curricula of Iran, a two-credit course has been proposed for implementation across the country. 展开更多
关键词 INTEGRATIVE MEDICINE TRADITIONAL MEDICINE COMPLEMENTARY MEDICINE Medical education CURRICULUM
做好军事临床航空医学科研课题应把握的几个问题
8
作者 徐先荣 《中华航空航天医学杂志》 CSCD 2019年第1期1-5,共5页
做好军事临床航空医学科研,首先应准确理解和把握军事临床航空医学的内涵,即军事临床航空医学是从事航空性病症的发病机制、诊断治疗、预防措施、医学鉴定的研究和实践,军事飞行人员身心疾病的诊断治疗、航空医学鉴定及身心疾病与飞行... 做好军事临床航空医学科研,首先应准确理解和把握军事临床航空医学的内涵,即军事临床航空医学是从事航空性病症的发病机制、诊断治疗、预防措施、医学鉴定的研究和实践,军事飞行人员身心疾病的诊断治疗、航空医学鉴定及身心疾病与飞行之间相互关系的研究和实践,飞行学员医学选拔、飞行人员改装体检、航天员临床医学选拔的实践和研究的航空医学分支学科.其次,要掌握军事临床航空医学的核心是军事飞行人员职业航空医学鉴定(简称医学鉴定),即为保证飞行安全和执行训练及作战任务,对飞行人员身心状况及岗位胜任能力做出客观评价.围绕医学鉴定和鉴定标准开展研究是军事临床航空医学的科研工作重点.第三,熟悉并正确应用军事临床航空医学术语,熟悉军事临床航空医学的科研课题类型,熟悉军事临床航空医学的科研管理模式和特点是完成军事临床航空医学科研全过程的质量保障. 展开更多
关键词 航空医学(Aerospace medicine) 临床医学(Clinical medicine) 军事医学(Military medicine) 科研选题 (Choice of proj ECT )
Medicine in Future and Advantages of Integrated Chinese and Western Medicine
9
作者 ZHANG Jiang-hua WU Mi-shan +2 位作者 WANG Yue-fen JIA Ying-min LI En 《中国结合医学杂志:英文版》 SCIE CAS CSCD 2019年第2期87-90,共4页
The history of medical development shows that oriental medicine, or traditional medicine, was born through medical practice during the times when science and technology were immature and underdeveloped, whereas with t... The history of medical development shows that oriental medicine, or traditional medicine, was born through medical practice during the times when science and technology were immature and underdeveloped, whereas with the development of science and technology, Western medicine, or modern medicine, was born through experimental analysis and research. With the development of medicine, the pros and cons of both medical systems become increasingly evident. How to integrate them and learn from each other will be the direction of future development of medicine. The formation and development of integrated medicine will, inevitably, usher in a new era for medicine. 展开更多
关键词 CHINESE MEDICINE WESTERN MEDICINE INTEGRATED CHINESE and WESTERN MEDICINE ADVANTAGE THINKING of model
Study on Agricultural Intellectual Property Protection and High-Quality Development of Traditional Chinese Medicine of Ginseng 预览
10
作者 Yuanpeng SUN Zhe WU +2 位作者 Xueqin SIMA Yanling SUN Zheng CHENG 《亚洲农业研究:英文版》 2019年第6期5-11,共7页
Agricultural intellectual property has the functions of carrying forward agricultural cultural heritage,encouraging agricultural scientific and technological innovation,cultivating the brand of agricultural products a... Agricultural intellectual property has the functions of carrying forward agricultural cultural heritage,encouraging agricultural scientific and technological innovation,cultivating the brand of agricultural products and so on. The protection and application of agricultural intellectual property rights can enhance the vitality,innovation and competitiveness of agricultural economy,and promote the strategy of high-quality agricultural development and rural revitalization. Ginseng is a traditional medicinal variety with superior characteristics in Northeast China,and it is one of the most famous " three treasures" in Northeast China. This paper introduces ginseng( Panax ginseng C. A. Mey.) and its medicinal value,analyzes the traditional knowledge,biological genetic resources,new plant varieties,patents,geographical indications,trademarks and other agricultural intellectual property resources of ginseng,studies the traditional Chinese medicine GAP certification and certification of " Three Agricultural Products" and the construction of the dominant area of agricultural product( Fusong ginseng) with Chinese characteristics,and explores the rural revitalization strategy and traditional Chinese medicine development strategy,ginseng agricultural intellectual property protection and high quality development strategy. 展开更多
关键词 GINSENG TRADITIONAL CHINESE MEDICINE AGRICULTURAL intellectual property rights Development STRATEGY of TRADITIONAL CHINESE MEDICINE Rural revitalization STRATEGY
在线阅读 免费下载
The differences and similarities between regional ethnic medicine and traditional Chinese medicine in the prevention and treatment of cancer pain 预览
11
作者 Hui-Li Shui Zhu Yang +4 位作者 Feng-Xi Long Wen-Qi Huang Bing Yang Zhen Zhang Dong-Xin Tang 《TMR肿瘤》 2019年第3期206-211,共6页
REM and TCM are both important parts of traditional medicine in China,and they have their own characteristics in the understanding and prevention of diseases.This article compares the understanding,the theoretical pre... REM and TCM are both important parts of traditional medicine in China,and they have their own characteristics in the understanding and prevention of diseases.This article compares the understanding,the theoretical prevention and treatment guidance and the clinical application of the REM and TCM on the cancer pain. 展开更多
关键词 REGIONAL ETHNIC MEDICINE Traditional Chinese MEDICINE Tumor Cancer PAIN SIMILARITIES and differences
在线阅读 下载PDF
浅谈虚拟现实技术在检验医学教学中的应用 预览
12
作者 陈安林 朱杰华 +2 位作者 向加林 杜文胜 何应中 《科教文汇》 2019年第10期99-101,共3页
随着计算机技术的发展,各种新技术在教学中的应用逐渐推广,犹如过去一段时间普遍应用的多媒体技术,微课、慕课等网络技术正在被鼓励应用于教学,目前虚拟现实(Virtual Reality,VR)技术在教学中的应用也在逐步普及,尤其在医学领域和医学... 随着计算机技术的发展,各种新技术在教学中的应用逐渐推广,犹如过去一段时间普遍应用的多媒体技术,微课、慕课等网络技术正在被鼓励应用于教学,目前虚拟现实(Virtual Reality,VR)技术在教学中的应用也在逐步普及,尤其在医学领域和医学教学领域逐渐被普遍应用,且有着其独特的特点。检验医学又有着本专业独有特点,若应用VR技术,可有利于学生巩固基础理论知识,掌握基本操作技能,使抽象化变具体化、可视化,便于学生理解理论与实践的结合。 展开更多
关键词 虚拟现实技术 教学 医学 检验医学
在线阅读 下载PDF
强直性脊柱炎的中医治疗进展 被引量:1
13
作者 张意侗 梁晖 +5 位作者 解纪惠 王冠军 魏鹏洲 李倩 王大伟 李承骏 《中国基层医药》 CAS 2019年第13期1659-1664,共6页
随着对AS致病因素研究的深入,虽然对其致病机制仍未完全了解,但在治疗方面,中医的多种治疗方法均取得了不错的效果,因此中医药治疗强直性脊柱炎具有一定优势,并展现出良好的应用前景。该研究通过计算机检索中国知网、万方数据库及维普... 随着对AS致病因素研究的深入,虽然对其致病机制仍未完全了解,但在治疗方面,中医的多种治疗方法均取得了不错的效果,因此中医药治疗强直性脊柱炎具有一定优势,并展现出良好的应用前景。该研究通过计算机检索中国知网、万方数据库及维普数据库等中文数据库,综述了国内近年来有关强直性脊柱炎的临床研究文献,报告了中医治疗强直性脊柱炎的最新进展。 展开更多
关键词 脊柱炎 强直性 医学 中国传统 临床医学 治疗学 针刺 灸法 数据库 文献型 综述
Analysis of 278 Cases of Clinical Application of Western Medicine with Traditional Chinese Medicine Syndrome Differentiation 预览
14
作者 王允昌 米登海 +2 位作者 王建平 张文杰 毛维武 《世界中西医结合杂志(英文)》 2019年第2期45-51,共7页
Since the beginning of the Western Learning, modern medicine has developed rapidly in China, and the integration of Chinese and western medicine has become inevitable. Since Zhang Xichun’s 'Medicine in the West&#... Since the beginning of the Western Learning, modern medicine has developed rapidly in China, and the integration of Chinese and western medicine has become inevitable. Since Zhang Xichun’s 'Medicine in the West', using traditional Chinese medicine theory to guide the practice of western medicine, through long-term clinical diagnosis, we gradually realized the advantages of applying western medicine according to TCM syndrome differentiation. Therefore, 278 patients from the Second People’s Hospital of Gansu Province from July 2015 to December 2017 were enrolled in the relevant departments of the Department of Internal Medicine. On the basis of routine treatment, TCM was obtained through inspection, inquiry, listening and smelling, palpation and pulse-taking. The syndrome type is based on the medicinal properties, menstruation and ef?cacy of more than ten kinds of western medicines, so that they can reach Chinese medicine(1)Therefore, this paper aims to improve the accuracy of western medicine use, reduce the incidence of adverse reactions, discover the new ef?cacy of western medicine,and promote the integration of Chinese and western medicine. 展开更多
关键词 WESTERN MEDICINE MEDICINAL properties TCM syndrome differentiation system WESTERN MEDICINE DIALECTICAL application research
在线阅读 下载PDF
Prevention and treatment of traditional Chinese medicine for elderly patients with colorectal cancer 预览
15
作者 Jia Wang Zhu Yang +5 位作者 Feng-Xi Long Jin-Lin Wu Ting Yu Xian-Man Wei Xun Liu Dong-Xin Tang 《TMR整合医学》 2019年第16期1-6,共6页
As China's population ages, the incidence of colorectal cancer in the elderly has increased. At present, colorectal cancer depends on surgery, radiotherapy and chemotherapy. Due to the characteristics of the elder... As China's population ages, the incidence of colorectal cancer in the elderly has increased. At present, colorectal cancer depends on surgery, radiotherapy and chemotherapy. Due to the characteristics of the elderly, postoperative recovery is slow, prone to postoperative complications and difficult to tolerate radiotherapy and chemotherapy have become the main problem hindering the disease. Based on the theory of prevention, the use of drugs from the perspective of constitution and etiology can prevent the occurrence of colorectal cancer in the elderly. Traditional Chinese medicine (TCM) combined with radiotherapy and chemotherapy can alleviate adverse reactions and improve treatment efficacy. TCM with surgical treatment can reduce the occurrence of postoperative complications and promote postoperative recovery. For patients with advanced colorectal cancer, TCM can play a role in fighting cancer and improving the quality of life of patients. For patients in stable phase, TCM can prevent tumor recurrence and metastasis. 展开更多
关键词 Traditional Chinese MEDICINE Colorectal cancer ELDERLY PHYSIQUE ETIOLOGY Western MEDICINE treatment
在线阅读 下载PDF
New Concept of Health with Perspective of Chinese Medicine
16
作者 WANG Ji YU Ruo-xi WANG Qi 《中国结合医学杂志:英文版》 SCIE CAS CSCD 2019年第9期712-715,共4页
Health medicine has been the direction of the development of medicine. However, the definition of health defined by Western medicine and traditional medicine cannot completely cover the ful meaning of health. Therefor... Health medicine has been the direction of the development of medicine. However, the definition of health defined by Western medicine and traditional medicine cannot completely cover the ful meaning of health. Therefore, we propose the new concept of health: health is a state of physical and mental harmony of different individuals in the life process with the environment, and good self-adaptive and regulation ability to natural and social environment. The new concept of health enriches the connotation of health defined by Western medicine and improves the understanding of health in the past, which provide the conceptual basis for further study on health medicine. 展开更多
关键词 HEALTH CONCEPT WESTERN MEDICINE Chinese MEDICINE
Blood-Letting Therapy for Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
17
作者 XIONG Xing-jiang WANG Peng-qian LI Sheng-jie 《中国结合医学杂志:英文版》 SCIE CAS CSCD 2019年第2期139-146,共8页
Objective:To evaluate the efficacy and safety of blood-letting therapy(BLT)in treatment of hypertension.Methods:A comprehensive electronic and manual bibliographic searches were performed in Cochrane Central Register ... Objective:To evaluate the efficacy and safety of blood-letting therapy(BLT)in treatment of hypertension.Methods:A comprehensive electronic and manual bibliographic searches were performed in Cochrane Central Register of Controlled Trials,Excerpt Medica Database(EMBASE),PubMed,China National Knowledge Infrastructure,Chinese Scientific Journal Database,Chinese Biomedical Literature Database,and Wanfang Database to identify randomized controlled trials(RCTs)in which hypertensive patients were treated with BLT or BLT plus antihypertensive drugs(BPAD)against placebo,no treatment or antihypertensive drugs.The Cochrane Risk Assessment Tool was used to assess the methodological quality of trials.The Review Manager 5.3 software was used for meta-analysis.Results:A total of 7 RCTs with 637 hypertensive patients from 1989 to 2017 were identified.Compared with antihypertensive drugs,blood pressure was significantly reduced by BLT(RR=1.21,95%CI:1.01 to 1.44,P=0.03;heterogeneity:P=0.06,I^2=60%)and BPAD(RR=1.25,95%CI,1.02 to 1.53,P=0.03;heterogeneity:P=0.01,I^2=71%).Moreover,a significant improvement in Chinese medicine syndrome by BLT(RR=1.32;95%CI:1.14 to 1.53,P=0.0002;heterogeneity:P=0.53,I^2=0%)and BPAD(RR=1.47;95%CI:1.06 to 2.04,P=0.02;heterogeneity:P=0.13,I^2=56%)was identified.The reported adverse effects were well tolerated.Conclusions:Although some positive findings were identified,no definite conclusions regarding the efficacy and safety of BLT as complementary and alternative approach for treatment of hypertension could be drew due to the generally poor methodological design,significant heterogeneity,and insufficient clinical data.Further rigorously designed trials are warranted to confirm the results. 展开更多
关键词 blood-letting THERAPY PHLEBOTOMY BLOOD pressure Chinese MEDICINE COMPLEMENTARY and alternative MEDICINE systematic review META-ANALYSIS randomized controlled trials
日本汉方用药用量特点研究
18
作者 陈丽名 夏天媛 +1 位作者 郭玉娜 樊露芮 《国际中医中药杂志》 2019年第9期911-915,共5页
日本汉方医学源于中国并在长期发展中结合自身实践有所创新,分析汉方用药特点对我国中医学发展有借鉴意义。本文对日本厚生劳动省颁布的常用汉方的组方药味总数、全方总量、平均用量、全方最大用量及全方最小用量进行梳理统计。结果显示... 日本汉方医学源于中国并在长期发展中结合自身实践有所创新,分析汉方用药特点对我国中医学发展有借鉴意义。本文对日本厚生劳动省颁布的常用汉方的组方药味总数、全方总量、平均用量、全方最大用量及全方最小用量进行梳理统计。结果显示,日本汉方多源于经方;组方药味数较少,多为4~9味;全方总药量较小,多为15~25 g;平均单味药用量为3.16 g。日本汉方用量较小,其原因与汉方发展的历史沿革、服药习惯、国民体质等诸多因素有关。 展开更多
关键词 医学 汉方 医学 日本传统 经方 剂量 中外交流史
Development and validation of the perioperative recovery scale for integrative medicine 预览
19
作者 Li Zhou Bi-Ying Su +5 位作者 Shao-Nan Liu Xiao-Yan Li Li-Xing Cao Li-Ming Lu Ze-Huai Wen Zhi-Qiang Chen 《TMR传统医学研究》 2019年第4期184-194,共11页
Purpose: The aim of this study is to develop and validate a scale for perioperative recovery with integrative medicine. Methods: The procedures for developing the scale included a review of both modern and ancient lit... Purpose: The aim of this study is to develop and validate a scale for perioperative recovery with integrative medicine. Methods: The procedures for developing the scale included a review of both modern and ancient literature, other perioperative scales or questionnaire references, an expert consultation, and interviews with patients and surgeons following standard procedures. Primary face and content validity were assessed through a small-scale patient survey of 50 patients. A final evaluation based on the patient survey was conducted among 354 patients (age range 16-75) from the same hospital. This included testing the perioperative recovery scale for integrative medicine (PRSIM) for scaling properties, reliability, validity and responsiveness. Results: The PRSIM, a 20-item scale, was modified from an initial version transcript which included 122 items. The 20 items in the PRSIM covered five domains: direct influence, indirect influence, activity, mental function and general health perceptions. Five factors extracted from an exploratory factor analysis demonstrated a desirable model fit. A confirmatory factor analysis further indicated that the PRSIM had a good fit with the same sample. A data analysis of the PRSIM with 349 patients showed that it had good internal consistency (α> 0.7), test-retest reliability (ICC > 0.4) and split half reliability (α= 0.66). Conclusions: The PRSIM can serve as a valuable instrument for assessing patient perioperative recovery in integrative medicine. It is acceptable for patients in the perioperative period undergoing treatment by either Chinese or integrative medicine, and has good psychometric properties. Registration number: ChiCTR-TRC-09000527. 展开更多
关键词 PRSIM instrument PSYCHOMETRIC test Reliability Validity RESPONSIVENESS Chinese MEDICINE INTEGRATIVE MEDICINE
在线阅读 下载PDF
Effectiveness of Integrative Medicine Therapy on Coronary Artery Disease Prognosis: A Real-World Study
20
作者 ZHAO Kang TIAN Jin-fan +7 位作者 ZHAO Cong YUAN Fei GAO Zhu-ye LI Li-zhi LIU Hong-xu WANG Xian GE Chang-jiang LU Shu-zheng 《中国结合医学杂志:英文版》 SCIE CAS CSCD 2019年第1期9-15,共7页
Objective: To evaluate the effectiveness of integrative medicine(IM) on patients with coronary artery disease(CAD) and investigate the prognostic factors of CAD in a real-world setting. Methods: A total of 1,087 hospi... Objective: To evaluate the effectiveness of integrative medicine(IM) on patients with coronary artery disease(CAD) and investigate the prognostic factors of CAD in a real-world setting. Methods: A total of 1,087 hospitalized patients with CAD from four hospitals in Beijing, China were consecutively selected between August 2011 and February 2012. The patients were assigned to two groups based on the treatment: Chinese medicine(CM) plus conventional treatment, i.e., IM therapy(IM group); or conventional treatment alone(CT group). The endpoint was major adverse cardiac events [MACE; including cardiac death, myocardial infarction(MI), and revascularization]. Results: A total of 1,040 patients finished the 2-year follow-up. Of them, 49.4%(514/1,040) received IM therapy. During the 2-year follow-up, the total incidence of MACE was 11.3%. Most of the events involved revascularization(9.3%). Cardiac death/MI occurred in 3.0% of cases. For revascularization, logistic stepwise regression analysis revealed that age 65 years [odds ratio(OR), 2.224], MI(OR, 2.561), diabetes mellitus(OR, 1.650), multi-vessel lesions(OR, 2.554), baseline high sensitivity C-reactive protein level 3 mg/L(OR, 1.678), and moderate or severe anxiety/depression(OR, 1.849) were negative predictors(P<0.05); while anti-platelet agents(OR, 0.422), β-blockers(OR, 0.626), statins(OR, 0.318), and IM therapy(OR, 0.583) were protective predictors(P<0.05). For cardiac death/MI, age 65 years(OR, 6.389) and heart failure(OR, 7.969) were negative predictors(P<0.05), while statin use(OR, 0.323) was a protective predictor(P<0.05) and IM therapy showed a beneficial tendency(OR, 0.587), although the difference was not statistically significant(P=0.218). Conclusion: In a real-world setting, for patients with CAD, IM therapy was associated with a decreased incidence of revascularization and showed a potential benefit in reducing the incidence of cardiac death or MI. 展开更多
关键词 CORONARY ARTERY disease Chinese MEDICINE INTEGRATIVE MEDICINE EFFECTIVENESS real-world STUDY
上一页 1 2 250 下一页 到第
使用帮助 返回顶部 意见反馈