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Estimation of Cytokines Involved in Acute-Phase Wound Infection with Reference to Residence Time of Patients in Hospitals 预览
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作者 Mohemid M. Al-Jebouri Balsam Yahya R. Al-Mahmood 《炎症(英文)》 2019年第1期1-10,共10页
Background: Cytokines have a major role in mediating immunity as well as inflammation. The main proinflammatory cytokines are activated after injury and implicated in healing interleukin-1 (IL-1), interleukin-6 (IL-6)... Background: Cytokines have a major role in mediating immunity as well as inflammation. The main proinflammatory cytokines are activated after injury and implicated in healing interleukin-1 (IL-1), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α). High levels of IL-6 are recorded at initial inflammatory response and start decreasing down to eight day of wounding while TNF-α level remained static and IL-1α levels showed a different pattern of change following injury and consequence of infection. Methodology: This study was conducted in Al-Kindy and Al-Wasity hospitals in Baghdad on 200 patients suffering from wounds. One hundred patients were with acute wounds infection and the other 100 patients wounded but without infection and considered as control. Interleukin-1α (IL-1α), interleukin-TNF-α (TNF-α) and interleukin-6 (IL-60) were determined utilizing ELISA kit sandwich methods (Elabscience, USA). Results: The present study revealed that the values of IL-1α, and TNF-α at 48 hours of hospitalization were 23.547 and 27.177 pg/ml among patients with infected wounds respectively, and 7.05 and 28.127 pg/ml among patients without wound infections respectively. While IL-6 showed a highest level at 96 hours of residence in hospital and the value was 183.43 pg/ml for patients with infected wounds, and the value of the same interleukin was 88.696 pg/ml at 72 hours of residence of patients without wound infections. Conclusions: Interleukin-1α elevated after 24 hr of infection and then decreased. Proinflammatory cytokines (IL-6) was detectable within 24 hr of infection. The highest concentration of IL-6 was seen with mixed bacteria and followed by gram negative bacteria and this probably due to lipopolysaccharide secretion caused an increase of IL-6 in blood circulation. Irregular changes were seen in TNF-α values with durations of patients stay in hospitals. 展开更多
关键词 Acute-Phase Infection WOUNDS CYTOKINES HOSPITAL Stay PATIENTS Iraq
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MEBT/MEBO对小鼠烧伤创面组织中K19表达的影响及作用机制 预览
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作者 李雄 彭浩 贺全勇 《中国烧伤创疡杂志》 2019年第1期24-33,共10页
目的探究烧伤创疡再生医疗技术(moist exposed burn therapy/moist exposed burn ointment, MEBT/MEBO)对烧伤创面组织中角蛋白19 (keratin 19, K19)表达的影响及可能的作用机制。方法选取15只健康雄性昆明小鼠,按照随机数表法随机选取... 目的探究烧伤创疡再生医疗技术(moist exposed burn therapy/moist exposed burn ointment, MEBT/MEBO)对烧伤创面组织中角蛋白19 (keratin 19, K19)表达的影响及可能的作用机制。方法选取15只健康雄性昆明小鼠,按照随机数表法随机选取5只作为对照组,10只建立深Ⅱ度烫伤模型后随机分为模型组与治疗组,其中治疗组小鼠创面采用湿润烧伤膏进行处理、模型组小鼠创面采用生理盐水进行处理、对照组小鼠背部脱毛后不做任何处理,1周后取皮肤或创面组织并通过免疫组织化学染色、蛋白质印迹(Western blot)及定量聚合酶链反应(quantitative polymerase chain reaction, Q-PCR)等技术检测自噬相关蛋白Beclin-1、LC3及K19的表达水平。结果治疗第1-7天,治疗组小鼠创面清洁,并始终保持湿润状态,且随着治疗时间的延长逐渐呈现上皮化状态;模型组小鼠创面逐渐加深,并出现感染征象。治疗1周后,免疫组织化学染色法及Western blot法检测结果显示,3组小鼠皮肤或创面组织中Beclin-1、LC3及K19表达水平对比,治疗组>模型组>对照组,P均<0.01,差异具有统计学意义;除Western blot法检测结果显示治疗组与模型组小鼠创面组织中LC3表达水平对比,P>0.05外,其余各检测结果均显示小鼠皮肤或创面组织中Beclin-1、LC3及K19表达水平两两对比,P<0.01,差异具有统计学意义。Q-PCR技术检测结果显示,3组小鼠皮肤或创面组织中K19 mRNA表达水平对比,治疗组>模型组>对照组,P <0.01,差异具有统计学意义;3组小鼠皮肤或创面组织中K19mRNA表达水平两两对比,P均<0. 01,差异具有统计学意义。结论 MEBT/MEBO促进烧伤创面愈合可能与增加创面组织中K19的表达有关,而诱导自噬相关蛋白的高表达可能是其具体机制之一。 展开更多
关键词 烧伤创疡再生医疗技术 烧伤 创面 角蛋白19 自噬相关蛋白 LC3 Beclin-1
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Clinical characteristics of 1653 injured motorcyclists and factors that predict mortality from motorcycle crashes in Malaysia
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作者 Henry Tan Chor Lip Jih Huei Tan +3 位作者 Yuzaidi Mohamad Affirul Chairil Ariffin Rizal Imran Tuan Nur 'Azmah Tuan Mat 《中华创伤杂志:英文版》 CAS CSCD 2019年第2期69-74,共6页
Purpose: Amongst the ASEAN countries, Malaysia has the highest road fatality risk (>15 fatalities per 100 000 population) with 50% of these fatalities involving motorcyclist. This contributes greatly to ward admiss... Purpose: Amongst the ASEAN countries, Malaysia has the highest road fatality risk (>15 fatalities per 100 000 population) with 50% of these fatalities involving motorcyclist. This contributes greatly to ward admissions and poses a significant burden to the general surgery services. From mild rib fractures to severe intra-abdominal exsa nguinations, the spectrum of cases man aged by surgeons resulting from motorcycle accidents is extensive. The objective of this study is to report the clinical characteristics and identify predictors of death in motorcycle traumatic injuries from a Malaysian trauma surgery centre. Methods: This is a prospective cross-sectional study of all injured motorcyclists and pillion riders that were admitted to Hospital Sultanah Aminah and treated by the trauma surgery team from May 2011 to February 2015. Only injured motorcyclists and pillion riders were included in this study. Patient demography and predictors leading to mortality were identified. Significant predictors on univariate analysis were further analysed with multivariate analysis. Results: We included 1653 patients with a mean age of (35 ± 16.17) years that were treated for traumatic injuries due to motorcycle accidents. The mortality rate was 8.6%(142) with equal amount of motorcycle riders (788) and pillion riders (865) that were injured. Amongst the injured were male predominant (1 537) and majority of ethnic groups were the Malays (897) and Chinese (350). Severity of injury was reflected with a mean Revised Trauma Score (RTS) of 7.31 ± 1.29, New Injury Severity Score (NISS) of 19.84 ± 13.84 and Trauma and Injury Severity Score (TRISS) of 0.91 ± 0.15. Univariate and multivariate analysis revealed that age>35, lower GCS, head injuries, chest injuries, liver injuries, and small bowel injuries were significant predictors of motorcycle trauma related deaths with p < 0.05. Higher trauma severity represented by NISS, RTS and TRISS scores was also significant for death with p < 0.05. Conclusion: Age, lower GCS, presence of head, 展开更多
关键词 Motorcycles MORTALITY Exsanguinations Adult WOUNDS and injuries MALAYSIA
Analysis on the accident casualties influenced by several economic factors based on the traffic-related data in China from 2004 to 2016
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作者 Li-Lu Sun Dan Liu +1 位作者 Tian Chen Meng-Ting He 《中华创伤杂志:英文版》 CAS CSCD 2019年第2期75-79,共5页
Purpose:By studying the economic data related to road traffic accidents in recent 10 years,this paper explores the impact of various economic factors on the number of casualties in traffic accidents in China,and puts ... Purpose:By studying the economic data related to road traffic accidents in recent 10 years,this paper explores the impact of various economic factors on the number of casualties in traffic accidents in China,and puts forward related prevention and management measures.Methods:Based on five economic factors including the number of new health institutions,health investment,transportation investment and disposable income per capita,this paper collects the data of traffic accidents in 31 provinces and municipalities of China from 2004 to 2016 and estimates the parameters using fixed effect model.Results:The number of health institutions,health investment,transportation investment and disposable income per capita are negatively correlated with the number of traffic accident casualties;the number of new health institutions is positively correlated with the number of traffic accident casualties;health investment and transportation investment have a great impact on the number of road traffic accident casualties.Conclusion:Economic development has a positive impact on improving traffic conditions,but the increase in the number of new health institutions does not reduce the number of casualties in accidents.The irrational layout of health institutions and imperfect road traffic management mechanism should be taken into account. 展开更多
关键词 TRAFFIC accidents Economic factors WOUNDS and INJURIES
Road traffic safety:An analysis of the cross-effects of economic,road and population factors
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作者 Li-Lu Sun Dan Liu +1 位作者 Tian Chen Meng-Ting He 《中华创伤杂志:英文版》 CAS CSCD 2019年第5期290-295,共6页
Purpose:Through the study of economic,traffic and population data related to road traffic accidents from 2004 to 2016,this paper analyzed the impact of various factors on road traffic casualties in China,and provided ... Purpose:Through the study of economic,traffic and population data related to road traffic accidents from 2004 to 2016,this paper analyzed the impact of various factors on road traffic casualties in China,and provided theoretical basis and suggestions for the road traffic safety management in China.Methods:Based on three aspects(economy,road,population)with five factors(gross domestic product(GDP),traffic in vestme nt,new vehicle own ership,new road mileage and newly in creased population),this paper collected the re leva nt data of road traffic accidents in 31 provinces and cities in China,from 2004 to 2016.A panel model was established to carry out empirical analysis.Results:All factors have a significant impact on the number of road traffic accident casualties.When other factors remain unchanged,the number of road traffic casualties decreased by an average of 0.19 for every 100 million CNY increased in GDP.For every 100 million CNY increased in traffic investment,the number of road traffic casualties is reduced by an average of 13.93,indicating that economic development can improve road traffic safety to a certain extent.On the contrary,the growth in road mileage,new motor vehicles and population has increased the number of road traffic casualties.For every 10,000 km of new road mileage,the number of traffic accident casualties has increased by 284.04.For every 10,000 newboms,the number of road traffic casualties increased by 7.33;as the number of new motor vehicles increases by 10,000,the number of road traffic casualties increased by an average of 21.77.Conclusion:The increase of GDP and traffic investment can significantly reduce the number of road traffic casualties in China,which shows that economic development is essential to improve road traffic safety.The numbers of new road mileage,newly increased population and the new motor vehicles are positively correlated with the number of traffic accident casualties in traffic accidents,which reflects the existing problems in road design,distribution of road res 展开更多
关键词 ROAD traffic safety Panel data Economic road and POPULATION FACTORS WOUNDS and INJURIES
抗生素骨水泥在糖尿病足溃疡创面应用的临床效果
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作者 黄红军 牛希华 +5 位作者 杨冠龙 王丽英 石凡超 徐绍君 徐林刚 李永林 《中华烧伤杂志》 CAS CSCD 北大核心 2019年第6期464-466,共3页
目的探讨采用抗生素骨水泥治疗糖尿病足溃疡的临床效果。方法根据采用的治疗方式,将笔者单位2016年1月—2017年1月、2017年2月—2018年2月收治的符合入选标准的各18例糖尿病足溃疡患者分别纳入传统组(男11例、女7例,年龄53~79岁)、骨水... 目的探讨采用抗生素骨水泥治疗糖尿病足溃疡的临床效果。方法根据采用的治疗方式,将笔者单位2016年1月—2017年1月、2017年2月—2018年2月收治的符合入选标准的各18例糖尿病足溃疡患者分别纳入传统组(男11例、女7例,年龄53~79岁)、骨水泥组(男11例、女7例,年龄55~80岁)。传统组患者行常规清创+负压封闭引流,骨水泥组患者行常规清创+抗生素骨水泥覆盖。回顾性统计2组患者入院时及术后3、6、9、15d创面分泌物细菌培养阳性患者数,住院时间,手术次数,创面完全愈合时间。对数据行Fisher确切概率法检验、独立样本t检验。结果与传统组[(29±10)d、(4.6±1.2)次]比较,骨水泥组患者住院时间[(9±3)d]明显缩短、手术次数[(1.3±0.6)次]明显减少、术后各时间点创面分泌物细菌培养阳性患者数明显减少(t=8.177、9.896,P<0.05或P<0.01);2组患者入院时创面分泌物细菌培养阳性患者数和创面完全愈合时间比较,差异无统计学意义(t=0.175,P>0.05)。结论抗生素骨水泥治疗糖尿病足溃疡可减少术后创面分泌物细菌培养阳性患者数和手术次数,缩短患者住院时间。 展开更多
关键词 糖尿病足 溃疡 创面 抗生素骨水泥
Value of Zhuang medicine choerospondias axillaris bark for evaluating the expression of PTEN,VEGF in chronic wounds rats
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作者 Xiao-Wei He Xin Huang +2 位作者 Jia-Qi Di Bing Wang Xing Yin 《海南医科大学学报(英文版)》 2019年第11期1-4,共4页
Objective:To investigate the mechanism of treating chronic wounds in rats by using Zhuang medicine choerospondias axillaris bark.Methods: The whole layer skin defection 40 rats were used and randomly divided into 4 gr... Objective:To investigate the mechanism of treating chronic wounds in rats by using Zhuang medicine choerospondias axillaris bark.Methods: The whole layer skin defection 40 rats were used and randomly divided into 4 groups: normal group, model group, MEBO group, choerospondias group. The normal group and model group were given external deposited normal saline external application. MEBO group used MEBT/MEBO. Choerospondias group was given external deposited choerospondias axillaris bark water decoction external application. Detected cell ultrastructure, PTEN、VEGF mRNA after 12 d.Results: The organelle structure in MEBO group and choerospondias group were restored. In 12 d, PTEN in MEBO group and choerospondias group were lower, VEGF were higher than 1 d (P<0.05). PTEN in MEBO group and choerospondias group were lower, VEGF were higher than model group (P<0.05). MEBO group had no difference with choerospondias group (P>0.05). Conclusion: Choerospondias axillaris bark water decoction could remarkably improve the cell ultrastructure in chronic wounds, regulate the PTEN signal conduction effect, and promote wound healing. 展开更多
关键词 CHRONIC WOUNDS Choerospondias axillaris BARK Cell ULTRASTRUCTURE PTEN VEGF
钝性心脏损伤手术救治43例
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作者 高劲谋 孔令文 +4 位作者 李辉 都定元 李昌华 杨俊 赵山红 《中华胸心血管外科杂志》 CSCD 北大核心 2019年第9期541-545,共5页
目的探讨钝性心脏损伤的早期诊断、手术救治和疗效.方法回顾性分析2003年9月至2018年8月43例钝性心脏损伤手术患者病历资料,包括性别、年龄、伤因、术前诊断、手术距受伤时间、手术方式和效果.损伤原因中交通事故占48.8%(21/43),其中方... 目的探讨钝性心脏损伤的早期诊断、手术救治和疗效.方法回顾性分析2003年9月至2018年8月43例钝性心脏损伤手术患者病历资料,包括性别、年龄、伤因、术前诊断、手术距受伤时间、手术方式和效果.损伤原因中交通事故占48.8%(21/43),其中方向盘伤占71.4%(15/21).26例术前诊断依靠胸部CT、超声心动图等影像学方法;17例因典型心包压塞征或大量血胸伴休克紧急剖胸,术中证实.伤后1 h内手术占27.9%(12/43).手术行心包减压、血心包清除和心脏修补36例;心包疝钳闭松解和心脏复位3例;心包膈疝还纳修补4例.急诊室剖胸7例,成功率42.9%(3/7).结果全组死亡14例(32.6%),分别死于急诊室剖胸(4例)、术中(5例)和术后(5例).死因包括心脏损伤9例(1例主动脉横断);合并伤5例(肝伤大出血3例、特重型颅脑伤1例、颈髓损伤呼吸衰竭1例).29例生存患者中,心内结构损伤4例(二尖瓣2例、三尖瓣1例、室缺1例),2例分别于术后2周和3个月行瓣膜成形术,另2例临床观察和影像学复查证实自行改善.术后并发症包括肺不张3例(经气管切开、纤支镜和呼吸机等治疗后肺复张)、感染性心内膜炎1例(抗生素治愈).随访6~36个月,生存患者心功能和健康状况正常.结论及时诊断并行紧急剖胸术是钝性心脏损伤患者获救的关键.不提倡术前大量扩容和心包穿刺,必要时应果断实施急诊室剖胸. 展开更多
关键词 创伤 钝性心脏损伤 心包压塞 紧急剖胸术
烧伤创疡再生医疗技术治疗眼镜蛇咬伤疗效观察 预览
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作者 王世军 林欣欣 +1 位作者 陈福伟 杨旭 《中国烧伤创疡杂志》 2019年第3期202-208,共7页
目的对比观察烧伤创疡再生医疗技术治疗眼镜蛇咬伤创面的临床疗效。方法将2010年6月至2016年6月福建中医药大学附属人民医院收治的120例眼镜蛇咬伤致局部皮肤出现灰黑斑的患者随机分为治疗组(60例)与对照组(60例),其中治疗组患者采用烧... 目的对比观察烧伤创疡再生医疗技术治疗眼镜蛇咬伤创面的临床疗效。方法将2010年6月至2016年6月福建中医药大学附属人民医院收治的120例眼镜蛇咬伤致局部皮肤出现灰黑斑的患者随机分为治疗组(60例)与对照组(60例),其中治疗组患者采用烧伤创疡再生医疗技术治疗局部创面,对照组患者采用重组牛碱性成纤维细胞生长因子凝胶(贝复新)治疗局部创面,对比观察两组患者的创面愈合情况。结果治疗30d时,治疗组患者的总有效率为70.00%,对照组患者的总有效率为51.67%,两组对比,P<0.05,差异具有统计学意义;治疗60 d时,治疗组患者的总有效率为96.67%,对照组患者的总有效率为86.67%,两组对比,P<0.05,差异具有统计学意义;最终两组患者创面均完全愈合,其中治疗组患者创面愈合时间为(43.63±20.48)d,对照组患者创面愈合时间为(66.93±36.45)d,两组对比,P<0.05,差异具有统计学意义。结论烧伤创疡再生医疗技术治疗眼镜蛇咬伤创面,可有效促进创面愈合,缩短创面愈合时间,疗效明显优于贝复新,值得临床推广应用。 展开更多
关键词 烧伤创疡再生医疗技术 蛇咬伤 创面 湿润烧伤膏 贝复新 疗效
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脂肪干细胞在炎性创面中的应用及前景 预览
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作者 张立明 蔡洁云 +1 位作者 潘福强 王静 《中国组织工程研究》 CAS 北大核心 2019年第25期4089-4093,共5页
背景:1998年人胚胎干细胞成功获得后,临床医师开始尝试应用干细胞治疗各种创伤,其中一个重要机制是其能够调节创面炎症。目的:探讨脂肪干细胞在创面炎症中的应用及前景。方法:由第一作者用计算机检索中国知网数据库和Pub Med数据库1999... 背景:1998年人胚胎干细胞成功获得后,临床医师开始尝试应用干细胞治疗各种创伤,其中一个重要机制是其能够调节创面炎症。目的:探讨脂肪干细胞在创面炎症中的应用及前景。方法:由第一作者用计算机检索中国知网数据库和Pub Med数据库1999至2018年10月的文献,检索词分别为"脂肪干细胞,创面,炎症"和"adipose-derived stem cells,wound,inflammation",选择内容与脂肪干细胞、创面、炎症相关的文章,同一领域文献则选择近期发表或发表在权威杂志的文章。结果与结论:创面修复是一个复杂有序的变化过程,创面炎症与创面修复的结果密切相关。随着再生医学的发展,干细胞的应用为创面修复带来了新的方法。脂肪干细胞因其自我增殖和多向分化能力强、易获取、储量丰富等特点在创面炎症中有着广阔的应用前景,仍是目前促进创面愈合的最热门研究课题之一。 展开更多
关键词 干细胞 脂肪干细胞 间充质干细胞 创面 炎症 创面愈合 创面修复 综述
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整体性护理对糖尿病烧伤患者创面治疗的效果观察 预览
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作者 陈翠娟 张育淑 《糖尿病新世界》 2019年第15期13-15,共3页
目的研究整体性护理对糖尿病烧伤患者创面治疗的效果。方法选取2018年1—12月该院收治的糖尿病烧伤患者54例,采用随机分组方式分为对照组与实验组,每组27例。其中对照组予以常规护理干预,实验组在此基础上予以整体性护理干预,观察两组... 目的研究整体性护理对糖尿病烧伤患者创面治疗的效果。方法选取2018年1—12月该院收治的糖尿病烧伤患者54例,采用随机分组方式分为对照组与实验组,每组27例。其中对照组予以常规护理干预,实验组在此基础上予以整体性护理干预,观察两组患者创面治疗效果。结果实验组在创面愈合总有效率、血糖水平、护理满意度上均显著优于对照组,对比差异有统计学意义(P<0.05)。结论对糖尿病烧伤患者采取整体性护理干预,能够有效改善创面愈合情况及血糖水平,提升护理满意度,建议临床推广。 展开更多
关键词 整体性护理 糖尿病 烧伤 创面 护理满意度
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A study of mortal让y risk factors among trauma referrals to trauma center, Shiraz, Iran, 2017
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作者 Mahnaz Yadollahi 《中华创伤杂志:英文版》 CAS CSCD 2019年第4期212-218,共7页
Purpose: Trauma is well known as one of the main causes of death and disability throughout the world. Identifying the risk factors for mortality in trauma patients can significantly improve the quality of care and pat... Purpose: Trauma is well known as one of the main causes of death and disability throughout the world. Identifying the risk factors for mortality in trauma patients can significantly improve the quality of care and patient outcomes, as well as reducing mortality rates. Methods:【n this retrospective cohort study, systematic randomization was used to select 849 patients referred to the main trauma center of south of Iran during a period of six months (February 2017-July 2017);the *patients case files were evaluated in terms of demographic information, pre- and post-accident conditions, clinical conditions at the time of admission and finally, accident outcomes. A logistic regression model was used to analyze the role of factors affecting mortality among subjects. Results: Among subjects, 60.4% were in the age-group of 15-39 years. There was a 10.4% mortality rate among patients and motor-vehicle accide nts were the most comm on mecha nism of injury (66.7%). Aging led to in creased risk of fatality in this study. For each urHt increase in Glasgow coma scale (GCS), risk of death decreased by about 40%(odds ratio (OR)= 0.63, 95% confidence interval (C/): 0.59—0.67). For each unit increase in injury severe score (ISS), risk of death increased by 10%(OR = 1.11%, 95% Cl: 1.08-1.14) and for each unit in crease in trauma revised injury severity score (TRISS), there was 18% decrease in the risk of fatality (OR = 0.82, 95% CI: 0.71-0.88). Conclusion: The most common cause of trauma and the most common cause of death from trauma was traffic accidents. It was also found that an increase in the ISS index increases the risk of death in trauma patients, but the increase in GCS, revised trauma score (RTS) and TRISS indices reduces the risk of death in trauma patients. The TRISS indicator is better predictor of traumatic death than other indicators. 展开更多
关键词 Risk factor FETAL MORTALITY WOUNDS and INJURIES
负压封闭引流技术(VSD)与传统治疗方法对复杂创面修复的临床对照研究 预览
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作者 陈锦波 何莉雅 +3 位作者 鲁培荣 吴燕兰 余俊喜 吴少坚 《世界复合医学》 2019年第3期33-36,共4页
目的观察负压封闭引流技术(vacuum sealing drainage,VSD)治疗复杂创面的临床效果及应用价值。方法收集2016年3月—2018年12月于该院外科住院的复杂创面患者60例,根据治疗方法分为VSD治疗(治疗组,n=30)和传统治疗(对照组,n=30),对比2组... 目的观察负压封闭引流技术(vacuum sealing drainage,VSD)治疗复杂创面的临床效果及应用价值。方法收集2016年3月—2018年12月于该院外科住院的复杂创面患者60例,根据治疗方法分为VSD治疗(治疗组,n=30)和传统治疗(对照组,n=30),对比2组治疗效果、疼痛评分。结果治疗组治愈、显效、有无效患者数分别为17、8、5例,总有效率为83.3%,对照组为23.3%,两组差异有统计学意义(χ^2=24.60,P<0.05)。与治疗前相比,两组患者疼痛评分都显著下降。术后治疗组功能障碍和疼痛评分显著低于对照组,差异有统计学意义(P<0.01)。结论VSD是能够彻底去除腔隙或创面分泌物和坏死组织,促进创面愈合,对复杂创面治疗疗效显著,缓解治疗期间患者疼痛及心理压力,值得临床推广应用。 展开更多
关键词 负压封闭引流技术 创面 复杂
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MEBO药纱治疗Wagner 3级糖尿病足疗效观察 预览
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作者 甄景志 陈强 +1 位作者 杨东亮 伍淑敏 《中国烧伤创疡杂志》 2019年第2期96-100,共5页
目的分析探讨湿润烧伤膏(moist exposed burn ointment, MEBO)药纱治疗Wanger 3级糖尿病足的临床疗效。方法选取2015年3月至2016年11月台山市中医院外科收治的60例Wanger 3级糖尿病足患者作为研究对象,并按照随机数表法将其随机分为试验... 目的分析探讨湿润烧伤膏(moist exposed burn ointment, MEBO)药纱治疗Wanger 3级糖尿病足的临床疗效。方法选取2015年3月至2016年11月台山市中医院外科收治的60例Wanger 3级糖尿病足患者作为研究对象,并按照随机数表法将其随机分为试验组(30例)和对照组(30例),其中试验组患者采用MEBO药纱治疗,对照组患者采用凡士林油纱治疗,对比观察两组患者自受试之日起至创面愈合的换药次数、每次换药所需时间、换药费用、创面愈合时间、揭除敷料时的疼痛程度及临床疗效等。结果试验组患者的换药次数为(45.5±9.2)次、换药时间为(11.1±1.4) min、换药费用为(1255.36±171.65)元、创面愈合时间为(43.2±5.5) d,均明显优于对照组患者的换药次数(59.7±10.5)次、换药时间(17.7±2.1) min、换药费用(1693.60±209.94)元、创面愈合时间(52.5±7.4) d,P均<0.01,差异具有统计学意义;治疗第8天,试验组患者揭除敷料时创面无疼痛者17例、轻度疼痛者9例、中度疼痛者3例、重度疼痛者1例,明显优于对照组的轻度疼痛者6例、中度疼痛者15例、重度疼痛者9例,P<0.01,差异具有统计学意义;治疗6周后,试验组患者中治愈24例、好转5例、无效1例,明显优于对照组的治愈12例、好转9例、无效9例,P<0.01,差异具有统计学意义。结论 MEBO药纱可有效促进Wanger 3级糖尿病足创面的愈合,缩短创面愈合时间,减少换药次数及换药时间,降低揭除敷料时的疼痛程度及换药费用,疗效显著。 展开更多
关键词 湿润烧伤膏 药纱 凡士林 糖尿病足 创面 疗效
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糖尿病足部溃疡创面的综合护理
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作者 马青 《双足与保健》 2019年第14期65-66,共2页
目的分析综合护理在糖尿病足部溃疡护理中的实施方法及应用价值。方法选择该院2017年1月—2018年12月收治的84例糖尿病足部溃疡患者,以护理措施不同为依据分组,对两组创面愈合情况及护理满意度情况。结果观察组护理后14 d创面分泌物细... 目的分析综合护理在糖尿病足部溃疡护理中的实施方法及应用价值。方法选择该院2017年1月—2018年12月收治的84例糖尿病足部溃疡患者,以护理措施不同为依据分组,对两组创面愈合情况及护理满意度情况。结果观察组护理后14 d创面分泌物细菌培养阳性率4.76%(2/42),创面愈合时间(25.73±5.80)d,恢复情况各指标均显著优于对照组,差异有统计学意义(P<0.05);观察组护理满意度97.62%(41/42)显著高于对照组83.33%(35/42),差异有统计学意义(P<0.05)。结论综合护理干预可有效减少糖尿病足部溃疡患者的创面细菌感染,注重控制感染、皮肤护理及血糖控制,有利于缩短创面愈合时间,提高患者满意度,促进康复。 展开更多
关键词 糖尿病 足部溃疡 综合护理 创面 愈合
烧伤创疡再生医疗技术治疗创疡的典型病例介绍 预览
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《中国烧伤创疡杂志》 2019年第3期178-185,共8页
病例1:崔某某,女,45岁。
关键词 湿润烧伤膏 烧伤创疡再生医疗技术 创伤 溃疡 病例报告
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马应龙麝香痔疮膏联合地奥司明片对混合痔术后创面水肿的防治效果 预览
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作者 邓开智 冷明敏 唐建 《世界中医药》 CAS 2019年第4期946-949,共4页
目的:探讨马应龙麝香痔疮膏联合地奥司明片对混合痔术后创面水肿的防治效果。方法:选取2015年10月至2017年10月德阳市人民医院收治的混合痔术后患者144例作为研究对象,随机分为对照组和观察组,每组72例。对照组患者给予迈之灵片口服治疗... 目的:探讨马应龙麝香痔疮膏联合地奥司明片对混合痔术后创面水肿的防治效果。方法:选取2015年10月至2017年10月德阳市人民医院收治的混合痔术后患者144例作为研究对象,随机分为对照组和观察组,每组72例。对照组患者给予迈之灵片口服治疗,观察组给予地奥司明片口服,马应龙麝香痔疮膏涂抹于肛门创面附近,2组均连续治疗7d,随访6个月。比较2组患者临床疗效,评估2组患者术后创面疼痛、水肿恢复情况、肛门功能,检测并比较2组创面P物质(SP)含量。结果:治疗后观察组总有效率为95.83%显著高于对照组的79.17%(P<0.01)。术后2~6d,2组创面NRS评分和水肿评分逐渐降低(P<0.01),且术后4d、6d观察组创面NRS评分和水肿评分低于对照组,疼痛和水肿缓解时间较对照组缩短(P<0.01)。从出院至术后6个月,2组Wexner评分逐渐降低(P<0.01),观察组出院时Wexner评分低于对照组(P<0.01),术后3~6个月2组Wexner评分差异无统计学意义(P>0.05)。术后2~6d,2组创面SP含量呈现逐渐升高趋势(P<0.01),且观察组术后4d、6d创面SP含量明显高于对照组(P<0.01)。结论:混合痔术后患者应用马应龙麝香痔疮膏联合地奥司明片治疗可加速创面疼痛及水肿的缓解,改善患者肛门功能,可能与增加创面组织中SP含量有关。 展开更多
关键词 混合痔 马应龙麝香痔疮膏 地奥司明 水肿 疼痛 P物质 疗效 创面
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全厚皮片联合颗粒脂肪移植修复眼眶区皮肤缺损 预览
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作者 柳晓杰 白晓东 徐潇 《中国美容医学》 CAS 2019年第7期70-72,共3页
目的:观察应用自体全厚皮片移植联合二期自体颗粒脂肪移植修复眼眶区皮肤缺损的疗效观察。方法:2010年1月-2018年1月面部烧创伤及面眶区皮肤肿瘤切除术后修复6例,其中自体全厚皮片移植修复2个月后联合自体颗粒脂肪移植3例(A组),单纯自... 目的:观察应用自体全厚皮片移植联合二期自体颗粒脂肪移植修复眼眶区皮肤缺损的疗效观察。方法:2010年1月-2018年1月面部烧创伤及面眶区皮肤肿瘤切除术后修复6例,其中自体全厚皮片移植修复2个月后联合自体颗粒脂肪移植3例(A组),单纯自体全厚皮片移植修复3例(B组)。随访1年,对两组术区色素沉着和质地评分比较。结果:A组移植皮片色素沉着逐渐减轻,评分(2.17±0.41)分;术区质地满意,评分(2.67±0.51)分。B组移植区与周围皮肤有色差,评分(1.17±0.42)分;移植皮片质地皮肤差异明显,评分(1.67±0.52)分。组间比较差异有统计学意义(P<0.01)。结论:全厚皮片移植联合自体颗粒脂肪移植填充,可有效改善移植后皮片色素沉着及质地。 展开更多
关键词 创面 眼眶区 自体皮片移植 颗粒脂肪移植 烧伤 创伤 色素沉着 皮肤肿瘤
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钝性胸部创伤所致多发性肋骨骨折或肺挫伤患者血清表面活性蛋白D和白介素6水平变化及其临床意义 预览
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作者 戴宁凰 郑中锋 +2 位作者 李威 陆波 庄淮千 《实用心脑肺血管病杂志》 2019年第7期97-99,共3页
目的分析钝性胸部创伤(BCT)所致多发性肋骨骨折或肺挫伤患者血清表面活性蛋白D(SP-D)和白介素6(IL-6)水平变化及其临床意义。方法选取2014年1月-2018年10月在南京鼓楼医院集团宿迁市人民医院胸外科住院的BCT所致多发性肋骨骨折患者106... 目的分析钝性胸部创伤(BCT)所致多发性肋骨骨折或肺挫伤患者血清表面活性蛋白D(SP-D)和白介素6(IL-6)水平变化及其临床意义。方法选取2014年1月-2018年10月在南京鼓楼医院集团宿迁市人民医院胸外科住院的BCT所致多发性肋骨骨折患者106例作为A组,BCT所致肺挫伤患者106例作为B组,同期在本院体检健康者106例作为对照组。比较A组与B组患者创伤情况,并比较三组受试者6 h、24 h、7 d血清SP-D和IL-6水平。结果(1)A组与B组患者创伤原因、创伤部位、创伤严重程度(ISS)评分、其他胸部创伤情况、全身创伤情况、肺不张及肺炎发生率、住院时间比较,差异无统计学意义(P>0.05)。(2)以对照组受试者血清SP-D和IL-6水平为常模,A组、B组患者创伤后6 h、24 h、7 d血清SP-D水平高于对照组,B组患者创伤后6 h、24 h、7 d血清SP-D水平高于A组(P<0.05);A组、B组患者创伤后6 h、24 h及B组患者创伤后7 d血清IL-6水平高于对照组,B组患者创伤后6 h、24 h血清IL-6水平高于A组(P<0.05)。结论 BCT所致多发性肋骨骨折或肺挫伤患者血清SP-D和IL-6水平明显升高,创伤后24 h内检测血清SP-D和IL-6水平有助于判断BCT病情严重程度。 展开更多
关键词 胸部损伤 肋骨骨折 挫伤 创伤 非贯通性 白介素6 表面活性物质蛋白质D
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Prevalence of musculoskeletal injuries and a proposal for neuromuscular training to prevent lower limb injuries in Brazilian Army soldiers: an observational study
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作者 Michele Zukauskas de Andrade Gomes Carlos Eduardo Pinfildi 《军事医学研究:英文版》 CAS CSCD 2019年第1期45-52,共8页
Background: The activities carried out by soldiers in the army involve great physical demands and require intense trainings to perform combat-specific tasks. Musculoskeletal injury is a potential threat to the health ... Background: The activities carried out by soldiers in the army involve great physical demands and require intense trainings to perform combat-specific tasks. Musculoskeletal injury is a potential threat to the health and physical integrity of the soldier. This study aimed to evaluate the prevalence of lower limb musculoskeletal injuries among soldiers and to propose a training protocol to prevent the most frequent injuries.Methods: This observational(cross-sectional) study recruited a sample of 103 soldiers who required medical attention,from a total 202 new battalion soldiers. The medical records(paper and online) had a form of running text. All data collected were recorded by the registered physicians of the battalion medical post. The records were analyzed by the following variables: medical diagnosis, injury site, mechanism, type of treatment, time loss, existence of previous injury,and recurring injury.Results: A total of 112 musculoskeletal injuries were diagnosed in 71 soldiers, and other types of diseases/injuries were diagnosed in the other soldiers. Joint pain accounted for 55.4% of the diagnoses. The knee was the most affected site, while trauma and overload were the most common mechanisms of injury. Drug treatment was used most frequently, accounting for 58% of the cases. The majority of the sample obtained a temporary leave of absence for1 to 6 days or not at all. Previous injuries and recurrence were not presented as risk factors for injury. With the data received, a protocol for the prevention of injuries to the lower limbs was proposed.Conclusions: This study indicated that the most frequent site of injury is the knee, and joint pain is the most common diagnosis. These results may support the necessity to develop a neuromuscular training protocol to prevent lower limb injuries, which we suggest to be applied in future studies. 展开更多
关键词 Physical therapy WOUNDS and injuries Primary prevention Lower EXTREMITY PROPRIOCEPTION Military personnel
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