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The relative changes of a sea surface temperature in the South China Sea since the Pliocene 预览
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作者 Dongjie Bi Daojun Zhang +4 位作者 Shikui Zhai Xinyu Liu Chun Xiu Xiaofeng Liu Aibin Zhang 《海洋学报:英文版》 SCIE CAS CSCD 2019年第3期78-92,共15页
The reconstruction of sea surface temperature(SST) is a key issue in research on paleoceanography. The recently related studies are mainly concentrated on the Quaternary. The skeletons of a typical species of benthoni... The reconstruction of sea surface temperature(SST) is a key issue in research on paleoceanography. The recently related studies are mainly concentrated on the Quaternary. The skeletons of a typical species of benthonic foraminifer(Amphistegina radiata) in the top 0–375.30 m interval of Well 'Xike-1' reef core, Shidao Island, the Xisha Islands, are uniformly selected. The ratios of magnesium to calcium concentrations and other indicators are analyzed by an electron microprobe analysis(EMPA) with the purpose of estimating the paleo-SSTs since the Pliocene and further investigating the periodic change law of paleoclimate in the South China Sea(SCS).Meanwhile, the geologic significance of paleoclimatic events in the SCS is discussed with global perspectives. The results indicate that the paleo-SSTs reconstructed by the ratios of magnesium to calcium concentrations in the SCS show a general periodic trend of 'high–low–high–low' in values changes since the Pliocene. By comparison,the fluctuations of reconstructed paleo-SSTs are much stronger in the Quaternary. Moreover, the variations of the ratios of magnesium to calcium concentrations in the A. radiata skeletons have recorded a series of major paleoclimatic events since the Pliocene, of which the Quaternary glaciation events and the Arctic ice cap forming events during the late Pliocene are more significant. Thus, using the changes of the ratios of magnesium to calcium concentrations in the A. radiata skeletons from Well 'Xike-1' reef core to reflect the relative changes of paleo-SSTs is a relatively feasible and reliable way in the SCS, which is also proved by the correlation of drilling cores characteristics in this area. 展开更多
关键词 the ratios of magnesium to calcium CONCENTRATIONS benthonic FORAMINIFERA sea surface temperature PALEOCLIMATIC events
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The Belt and Road:Geographical pattern and regional risks
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作者 WU Shaohong LIU Lulu +4 位作者 LIU Yanhua GAO Jiangbo DAI Erfu FENG Aiqing WANG Wentao 《地理学报:英文版》 SCIE CSCD 2019年第4期483-495,共13页
Building the Belt and Road is initiatives of China to promote win-win international cooperation in the new era,aiming at green,health,intellect and peace and the joint developme nt with people of the coun tries along ... Building the Belt and Road is initiatives of China to promote win-win international cooperation in the new era,aiming at green,health,intellect and peace and the joint developme nt with people of the coun tries along the route.Systematic an alysis on envir on mental characteristics,evolutionary tendency and future risks are certainly the scie ntific fun dame ntals of sustainable development for the Belt and Road construction.Applied remote sensing monitoring,statistical analysis,this paper investigates the regional characteristics of climate,topography,soil,hydrology,vegetation cover and terrestrial ecosystems production,as well as socio-economic conditions.Based on the regional characteristics,the Belt and Road is divided into 9 sub-regions:Central and Eastern Europe sub-region with cold and humid climate,Mongolia and Russia sub-region with cold and arid climate,Central and West Asia arid sub-region,Southeast Asia sub-region with warm and humid climate,Pakistan arid sub-region,Bangladesh-India-Myanmar sub-region with warm and humid climate,Eastern China monsoon sub-region,Northwest China arid sub-region and Tibetan Plateau sub-region.Combining modeling simulation with seenario projections,natural disaster assessment methodology is used to assess the risk of extreme events including heat waves,droughts and floods in the coming 30 years(2021-2050).Results show that,on the basis of the regional framework,the western Eurasia would be a warming trend;both sides of Qinghai-Tibet Plateau in high temperature and heat waves risk;Central and Eastern Europe sub-region with cold and humid climate in high drought risk;Bangladesh-lndia-Myanmar sub-region with warm and humid climate as well as Eastern China in high risk of flooding. 展开更多
关键词 the BELT and ROAD regional characteristics EXTREME EVENTS environmental change RISKS
Geochronology and geochemistry of Permo-Triassic sandstones in eastern Jilin Province(NE China):Implications for final closure of the Paleo-Asian Ocean 预览
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作者 Qingxiang Du Zuozhen Han +5 位作者 Xiaoli Shen Chao Han Zhigang Song Lihua Gao Mei Han Wenjian Zhong 《地学前缘:英文版》 CAS CSCD 2019年第2期683-704,共22页
In the eastern part of the Central Asian Orogenic Belt(CAOB) in northeastern(NE) China, scattered outcrops of molasse deposits mark the ending of an orogeny and are crucial for understanding the evolution of the Paleo... In the eastern part of the Central Asian Orogenic Belt(CAOB) in northeastern(NE) China, scattered outcrops of molasse deposits mark the ending of an orogeny and are crucial for understanding the evolution of the Paleo-Asian Ocean(PAO). However, the timing of tectonic events and the relationships among these strata remain controversial. To better constrain these geologic events, a comprehensive study of the detrital zircon U-Pb geochronology and geochemistry of the sandstones of the Kaishantun(KST) Formation and Kedao(KD) Group in eastern Jilin Province, NE China, was conducted. The KST Formation is traditionally considered a molasse deposit. The sandstones display low CIA, PIA and high ICV values and low Th/U and Rb/Sr ratios, which suggest that the rocks were derived from an immature intermediate-felsic igneous source and experienced a simple sedimentary recycling history with relatively weak chemical weathering. LA-ICP-MS U-Pb dating of detrital zircons from two samples of the KST Formation yields ages of 748-252 Ma, suggesting that the KST Formation was deposited between 254.5 Ma and 252 Ma in Late Permian. The zircons were mainly derived from the continental northern part of the North China Craton(NCC). In contrast, the U-Pb dating of detrital zircons from five samples of the KD Group yields ages of 2611-230 Ma, suggesting that the KD samples were deposited in the Early to Middle Triassic(ca. 248-233 Ma). The detrital zircon ages for the KD samples can be divided into groups with peaks at 2.5 Ga, 1.8 Ga, 800-1000 Ma, 500 Ma and 440-360 Ma, which suggest that the samples were derived from bidirectional provenances in the Jiamusi-Khanka Block and the NCC. These new data,combined with previously published results, suggest that at least three orogenic events occurred in central-eastern Jilin Province during the Early Permian(270-262 Ma), Early Triassic(254-248 Ma) and Middle-Late Triassic(242-227 Ma). The final closure of the PAO occurred during 242-227 Ma in the Middle-Late Triassic along the Changchun-Yanji sut 展开更多
关键词 DETRITAL zircon MOLASSE OROGENIC events Changchun-Yanji suture zone Paleo-Asian Ocean
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Risk Index Prediction of Civil Aviation Based on Deep Neural Network 预览
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作者 NI Xiaomei WANG Huawei CHE Changchang 《南京航空航天大学学报:英文版》 EI CSCD 2019年第2期313-319,共7页
Safety is the foundation of sustainable development in civil aviation.Although catastrophic accidents are rare,indicators of potential incidents and unsafe events frequently materialize.Therefore,a history of unsafe d... Safety is the foundation of sustainable development in civil aviation.Although catastrophic accidents are rare,indicators of potential incidents and unsafe events frequently materialize.Therefore,a history of unsafe data are considered in predicting safety risks.A deep learning method is adopted for extracting reactions in safety risks.The deep neural network(DNN)model for safety risk prediction is shown to extract complex data characteristics better than a shallow network model.Using extended unsafe data and monthly risk indices,hidden layers and iterations are determined.The effectiveness of DNN is also revealed in comparison with the traditional neural network.Through early risk detection using the method in the paper,airlines and the government can mitigate potential risk and take proactive measures to improve civil aviation safety. 展开更多
关键词 unsafe EVENTS risk index NEURAL network DENOISING auto ENCODER
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Prevention of macrovascular complications in patients with type 2 diabetes mellitus: Review of cardiovascular safety and efficacy of newer diabetes medications 预览
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作者 Ravi Kant Kashif M Munir +1 位作者 Arshpreet Kaur Vipin Verma 《世界糖尿病杂志:英文版(电子版)》 2019年第6期324-332,共9页
Lack of conclusive beneficial effects of strict glycemic control on macrovascular complications has been very frustrating for clinicians involved in care of patients with diabetes mellitus (DM). Highly publicized cont... Lack of conclusive beneficial effects of strict glycemic control on macrovascular complications has been very frustrating for clinicians involved in care of patients with diabetes mellitus (DM). Highly publicized controversy surrounding cardiovascular (CV) safety of rosiglitazone resulted in major changes in United States Food and Drug Administration policy in 2008 regarding approval process of new antidiabetic medications, which has resulted in revolutionary data from several large CV outcome trials over the last few years. All drugs in glucagon-like peptide-1 receptor agonist (GLP-1 RA) and sodium-glucose cotransporter-2 (SGLT-2) inhibitor classes have shown to be CV safe with heterogeneous results on CV efficacy. Given twofold higher CV disease mortality in patients with DM than without DM, GLP-1 RAs and SGLT-2-inhibitors are important additions to clinician’s armamentarium and should be second line-therapy particularly in patients with T2DM and established atherosclerotic CV disease or high risks for CV disease. Abundance of data and heterogeneity in CV outcome trials results can make it difficult for clinicians, particularly primary care physicians, to stay updated with all the recent evidence. The scope of this comprehensive review will focus on all major CV outcome studies evaluating CV safety and efficacy of GLP-1 RAs and SGLT-2 inhibitors. 展开更多
关键词 Newer antidiabetic MEDICATIONS Glucagon-like peptide-1 receptor agonist Sodium-glucose cotransporter-2 inhibitors Type 2 DIABETES MELLITUS Macrovascular complications CARDIOVASCULAR outcome trials Major CARDIOVASCULAR events HEART failure PREVENTION of HEART disease
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Why would sea-level rise for global warming and polar ice-melt? 预览
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作者 Aftab Alam Khan 《地学前缘:英文版》 CAS CSCD 2019年第2期481-494,共14页
Two major causes of global sea level rise such as thermal expansion of the oceans and the loss of landbased ice for increased melting have been claimed by some researchers and recognized by the IPCC.However, other cli... Two major causes of global sea level rise such as thermal expansion of the oceans and the loss of landbased ice for increased melting have been claimed by some researchers and recognized by the IPCC.However, other climate threat investigators revealed that atmosphere-ocean modeling is an imperfect representation, paleo-data consist of proxy climate information with ambiguities, and modern observations are limited in scope and accuracy. It is revealed that global warming and polar ice-melt although a reality would not contribute to any sea level rise. Floating-ice of the polar region on melting would reoccupy same displaced volume by floating ice-sheets. Land-ice cover in the polar region on melting can reduce load from the crust to activate elastic rebound that would raise land for its isostatic equilibrium.Such characteristics would not contribute to sea level rise. Equatorial bulge, polar flattening, elevation difference of the spheroidal surface between equator and pole with lower in the pole, strong gravity attraction of the polar region and week gravity attraction of the equatorial region, all these phenomena would play dominant role in preventing sea level rise. Palaeo-sea level rise and fall in macro-scale(10-100 m or so) were related to marine transgression and regression in addition to other geologic events like converging and diverging plate tectonics, orogenic uplift of the collision margin, basin subsidence of the extensional crust, volcanic activities in the oceanic region, prograding delta buildup, ocean floor height change and sub-marine mass avalanche. This study also reveals that geophysical shape, gravity attraction and the centrifugal force of spinning and rotation of the earth would continue acting against sea level rise. 展开更多
关键词 Global warming POLAR ice-melt EQUATORIAL BULGE POLAR FLATTENING GEOLOGIC events Sea level rise
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Rockfall seismic features analysis based on in situ tests:frequency, amplitude, and duration
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作者 Liang FENG Veronica PAZZI +2 位作者 Emanuele INTRIERI Teresa GRACCHI Giovanni GIGLI 《山地科学学报:英文版》 SCIE CSCD 2019年第5期955-973,共19页
In the seismic event classification,determining the seismic features of rockfall is significantly important for the automatic classification of seismic events because of the huge amount of raw data recorded by seismic... In the seismic event classification,determining the seismic features of rockfall is significantly important for the automatic classification of seismic events because of the huge amount of raw data recorded by seismic stations in continuous monitoring. At the same time, the rockfall seismic features are still not completely understood.This study concentrates on the rockfall frequency content, amplitude(ground velocity), seismic waveform and duration analysis, of an artificial rockfall test at Torgiovannetto(a former quarry in Central Italy). A total of 90 blocks were released in the test, and their seismic signals and moving trajectories were recorded by four tri-axial seismic stations and four cameras, respectively. In the analysis processing,all the artificial rockfall signal traces were cut separately and the seismic features were extracted individually and automatically. In this study, the relationships between a) frequency content and impacted materials, b) frequency content and the distance between block releasing position and seismic station(source-receiver distance) were discussed. As a result, we found that the frequency content of rockfall focuses on 10-60 Hz and 80-90 Hz within a source-receiver distance of 200 m, and it is well correlated with impacted material and source-receiver distance. To evaluate the difference between earthquake and rockfall, 23 clear earthquake signals recorded in a seven month-long continuous seismic monitoring, carried out with the four seismic stations, were picked out, according to the Italian national earthquakes database(INGV). On these traces we performed the same analysis as in the artificial rockfall traces, and two parameters were defined to separate rockfall events from earthquake noise. The first one, the amplitude ratio, is related to the amplitude variation of rockfall between two stations and is greater than that of earthquakes, because of the higher attenuation occurring for rockfall events, which consists in high frequencies whereas for earthquakes it consists 展开更多
关键词 ROCKFALL SEISMIC noise ANALYSIS Fourier TRANSFORM SEISMIC events classification Time-series ANALYSIS SEISMIC monitoring
Clinical outcomes and predictive model of platelet reactivity to clopidogrel after acute ischemic vascular events
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作者 Qi Ma Guang-Zhong Chen +2 位作者 Yu-Hu Zhang Li Zhang Li-An Huang 《中华医学杂志:英文版》 SCIE CAS CSCD 2019年第9期1053-1062,共10页
Background:High on-treatment platelet reactivity (HTPR) has been suggested as a risk factor for patients with ischemic vascular disease.We explored a predictive model of platelet reactivity to clopidogrel and the rela... Background:High on-treatment platelet reactivity (HTPR) has been suggested as a risk factor for patients with ischemic vascular disease.We explored a predictive model of platelet reactivity to clopidogrel and the relationship with clinical outcomes.Methods:A total of 441 patients were included.Platelet reactivity was measured by light transmittance aggregometry after receiving dual antiplatelet therapy.HTPR was defined by the consensus cutoff of maximal platelet aggregation >46% by light transmittance aggregometry.CYP2C19 loss-of-function polymorphisms were identified by DNA microarray analysis.The data were compared by binary logistic regression to find the risk factors.The primary endpoint was major adverse clinical events (MACEs),and patients were followed for a median time of 29 months.Survival curves were constructed with Kaplan-Meier estimates and compared by logrank tests between the patients with HTPR and non-HTPR.Results:The rate of HTPR was 17.2%.Logistic regression identified the following predictors of HTPR:age,therapy regimen,body mass index,diabetes history,CYP2C19^*2,or CYP2C19^*3 variant.The area under the curve of receiver operating characteristic for the HTPR predictive model was 0.793 (95% confidence interval:0.738–0.848).Kaplan-Meier analysis showed that patients with HTPR had a higher incidence of MACE than those with non-HTPR (21.1% vs.9.9%;χ^2 = 7.572,P = 0.010).Conclusions:Our results suggest that advanced age,higher body mass index,treatment with regular dual antiplatelet therapy,diabetes,and CYP2C19^*2 or CYP2C19^*3 carriers are significantly associated with HTPR to clopidogrel.The predictive model of HTPR has useful discrimination and good calibration and may predict long-term MACE. 展开更多
关键词 High on-treatment PLATELET REACTIVITY CLOPIDOGREL CYP2C19 Light TRANSMITTANCE AGGREGOMETRY ISCHEMIC vascular events
Biomarkers enhance the long-term predictive ability of the KAMIR risk score in Chinese patients with ST-elevation myocardial infarction
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作者 Jian-Jun Wang Yan Fan +5 位作者 Yan Zhu Jian-Dong Zhang Su-Mei Zhang Zhao-Fei Wan Hong-Ling Su Na Jiang 《中华医学杂志:英文版》 SCIE CAS CSCD 2019年第1期30-41,共12页
Background:The Global Registry of Acute Coronary Events (GRACE) score is recommended by current ST-elevation myocardial infarction (STEMI) guidelines.But it has inherent defects.The present study aimed to investigate ... Background:The Global Registry of Acute Coronary Events (GRACE) score is recommended by current ST-elevation myocardial infarction (STEMI) guidelines.But it has inherent defects.The present study aimed to investigate the more compatible risk stratification for Chinese patients with STEMI and to determine whether the addition of biomarkers to the Korea Acute Myocardial Infarction Registry (KAMIR) score could enhance its predictive value for long-term outcomes.Methods:A total of 1093 consecutive STEMI patients were included and followed up 48.2 months.Homocysteine,hypersensitive C-reactive protein (hs-CRP),and N-terminal pro-B-type natriuretic peptide (NT-proBNP) were detected.The KAMIR score and the GRACE score were calculated.The performance between the KAMIR and the GRACE was compared.The predictive power of the KAMIR alone and combined with biomarkers were assessed by the receiver-operating characteristic (ROC) curve.Results:The KAMIR demonstrated a better risk stratification and predictive ability than the GRACE (death:AUC = 0.802 vs.0.721,P<0.001;major adverse cardiovascular events (MACE):AUC = 0.683 vs.0.656,P<0.001).It showed that the biomarkers could independently predict death [homocysteine:HR= 1.019 (1.015–1.024),P<0.001;hs-CRP:HR= 1.052 (1.000–1.104),P= 0.018;NT-pro BNP:HR= 1.142 (1.004–1.280),P= 0.021] and MACE [homocysteine:HR= 1.019 (1.015–1.024),P<0.001;hs-CRP:HR= 1.012 (1.003–1.021),P= 0.020;NT-pro BNP:HR= 1.136 (1.104–1.168),P= 0.006].When they were used in combination with the KAMIR,the area under the ROC curve (AUC) significantly increased for death [homocysteine:AUC = 0.802 vs.0.890,Z = 5.982,P<0.001;hs-CRP:AUC = 0.802 vs.0.873,Z= 3.721,P<0.001;NT-pro BNP:AUC= 0.802 vs.0.871,Z = 2.187,P= 0.047;homocysteine,hs-CRP and NT-pro BNP:AUC = 0.802 vs.0.940,Z = 6.177,P<0.001] and MACE [homocysteine:AUC = 0.683 vs.0.771,Z= 6.818,P<0.001;hs-CRP:AUC= 0.683 vs.0.712,Z= 2.022,P= 0.031;NT-pro BNP:AUC= 0.683 vs.0.720,Z= 2.974,P= 0.003;homocysteine,hs-CRP and NT-pro BNP:AUC= 0.683 vs.0.789,Z= 6.900, 展开更多
关键词 ST-elevation MYOCARDIAL INFARCTION the Korea ACUTE MYOCARDIAL INFARCTION REGISTRY RISK SCORE the Global REGISTRY of ACUTE Coronary Events RISK SCORE homocysteine hypersensitive C-reactive protein N-terminal pro-B-type natriuretic peptide
How to Protect Physician Whistleblower—Patient Advocates—From Retaliation to Benefit Patients:A Legal Analysis Regarding Summary Suspension,Retaliation,Peer Review and Remedies 预览
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作者 Gil Mileikowsky MD Bartholomew Lee 《美中法律评论:英文版》 2019年第1期21-33,共13页
Public safety provides new statutory protections for whistleblowers:Legislation enacted in order to address medical error and failures of hospital quality systems has paradoxically created mechanisms that are used to ... Public safety provides new statutory protections for whistleblowers:Legislation enacted in order to address medical error and failures of hospital quality systems has paradoxically created mechanisms that are used to silence physicians and other caregivers who seek to protect patient safety by reporting breaches of professional quality and integrity.The laws enacted to protect patients can be and are currently misused to silence whistleblowers through punitive legal proceedings against patient safety advocates.Summary suspensions,deprivation of due process,and transfer of adjudicative authority to the hands of the institutions that most require oversight undermines transparency and patient advocacy.A modest set of statutory amendments,prophylactic and remedial,especially to prevent premature reporting of summary suspensions,can counteract these inequities and rebalance the House of Medicine so as to protect both patients and those who would seek to ensure their safety,so it may do no harm. 展开更多
关键词 PATIENT safety preventable adverse events due process SHAM peer review RETALIATION against WHISTLEBLOWER NPDB blacklisting Health Care Quality Improvement Act healthcare cost
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2018年国内外传染病领域重要事件回顾 预览
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作者 李硕 张云辉 +6 位作者 王永怡 李军 赵雅琳 闫晶晶 孙志杰 揣征然 姬军生 《传染病信息》 2019年第1期8-15,共8页
回首2018年,埃博拉病毒病在非洲死灰复燃,全球多个地区暴发霍乱,登革热病例数居高不下,尼帕病毒病在印度闪现,非洲猪瘟突然在中国多个地方出现等,使传染病工作者不断面临挑战。针对埃博拉病毒病的rVSV-ZEBOV疫苗及ZMapp、Remdesivir、mA... 回首2018年,埃博拉病毒病在非洲死灰复燃,全球多个地区暴发霍乱,登革热病例数居高不下,尼帕病毒病在印度闪现,非洲猪瘟突然在中国多个地方出现等,使传染病工作者不断面临挑战。针对埃博拉病毒病的rVSV-ZEBOV疫苗及ZMapp、Remdesivir、mAb114等多种药物的临床使用都取得较好的效果。首例免疫艾滋病的基因编辑婴儿诞生引起悍然大波。2018年中国国内上市药物数量和质量都有所提升,传染病领域主要涉及丙型肝炎、乙型肝炎以及艾滋病的药物呈现暴发式增长。本文仅对2018年传染病领域若干重点事件特别是我国的事件进行回顾。 展开更多
关键词 传染病 疫情 事件 回顾
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On a General Class of Semiparametric Hazards Regression Models for Recurrent Gap Times
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作者 Qin JIANG Hui ZHAO Hong QIN 《应用数学学报:英文版》 SCIE CSCD 2019年第3期549-563,共15页
In the article,we investigate a general class of semiparametric hazards regression models for recurrent gap times.The general class includes the proportional hazards model,the accelerated failure time model and the ac... In the article,we investigate a general class of semiparametric hazards regression models for recurrent gap times.The general class includes the proportional hazards model,the accelerated failure time model and the accelerated hazards models as special cases.The model is flexible in modelling recurrent gap times since a covariate effect is identified as having two separate components,namely a time-scale change on hazard progression and a relative hazards ratio.In order to infer the model parameters,the procedure is proposed based on estimating equations.The asymptotic properties of the proposed estimators are established and the finite sample properties are investigated via simulation studies.In addition,a lack of fit test is presented to assess the adequacy of the model and an application of data from a bladder cancer study is reported for illustration. 展开更多
关键词 GAP TIMES MODEL CHECKING RECURRENT events estimating equations SEMIPARAMETRIC MODEL
THE IMPACT OF MOUNTAIN TO BASIN WINDS ON THE DIURNAL VARIATION IN FOG OVER THE SICHUAN BASIN, CHINA
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作者 张福颖 刘海文 +3 位作者 朱玉祥 赵亮 段伯隆 傅宁 《热带气象学报:英文版》 SCIE 2019年第2期257-268,共12页
There is an increased demand for the accurate prediction of fog events in the Sichuan Basin(SCB) using numerical methods. A dense fog event that occurred over the SCB on 22 December 2016 was investigated. The results ... There is an increased demand for the accurate prediction of fog events in the Sichuan Basin(SCB) using numerical methods. A dense fog event that occurred over the SCB on 22 December 2016 was investigated. The results show that this dense fog event was influenced by the southwest of a low pressure with a weak horizontal pressure gradient and high relative humidity. This fog event showed typical diurnal variations. The fog began to form at 1800 UTC on 21 December 2016(0200 local standard time on 22 December 2016) and dissipated at 0600 UTC on 22 December 2016(1400 local standard time on 22 December 2016). The Weather Research and Forecasting model was able to partially reproduce the main features of this fog event and the diurnal variation in the local mountain to basin winds. The simulated horizontal visibility and liquid water content were used to characterize the fog. The mountain to basin winds had an important role in the diurnal variation of the fog event. The positive feedback mechanism between the fog and mountain to basin winds was good for the formation and maintain of the fog during the night. During the day, the mountain to basin wind displayed a transition from downslope flows to upslope flows. Water vapor evaporated easily from the warm, strong upslope winds, which resulted in the dissipation of fog during the day. The topography surrounding the SCB favored the lifting and condensation of air parcels in the lower troposphere as a result of the low height of the lifting condensation level. 展开更多
关键词 MOUNTAIN to BASIN winds FOG events WEATHER research and forecasting simulations TIBETAN PLATEAU
群体性事件的网络舆情及其治理模式研究--以成都七中实验学校事件为例 预览
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作者 罗静 《无线互联科技》 2019年第13期164-166,共3页
随着互联网技术的发展和网民用户数量的增加,过激言论、不良信息也随着自媒体的发展而不断涌现,信息传播群体间的“互动”在不断深化和升级。新的变化、新的舆论环境都会影响群体性舆情事件的主体意识。探索群体性事件舆情的形成过程,... 随着互联网技术的发展和网民用户数量的增加,过激言论、不良信息也随着自媒体的发展而不断涌现,信息传播群体间的“互动”在不断深化和升级。新的变化、新的舆论环境都会影响群体性舆情事件的主体意识。探索群体性事件舆情的形成过程,正确引导舆论的发展方向,有效应对舆论引发的危机,对维护社会稳定和群众安全有着重要指导意义。文章以成都七中实验学校事件为例,具体剖析舆论引导的重要性。 展开更多
关键词 事件 网络舆论 治理模式
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State-of-the-art: functional fluorescent probes for bioimaging and pharmacological research
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作者 Lu Lu Zhou-yue Wu +1 位作者 Xin Li Feng Han 《中国药理学报:英文版》 SCIE CAS CSCD 2019年第6期717-723,共7页
Cardiovascular diseases, neuropsychiatric disorders, and cancers seriously endanger human health. Mechanistic and pharmacological mechanisms of candidate drugs are central to the translational paradigm. Since many sig... Cardiovascular diseases, neuropsychiatric disorders, and cancers seriously endanger human health. Mechanistic and pharmacological mechanisms of candidate drugs are central to the translational paradigm. Since many signal transduction and molecular events are implicated in these diseases, a novel method to interrogate the key pharmacological mechanisms is required to accelerate innovative drug discovery. Much attention now focuses on the real-time visualization of molecular disease events to yield new insights to the pathogenesis of the diseases. This review focuses on recent advances in the development of chemical probes for imaging pathological events to facilitate the study of the underlying pharmacodynamics and toxicity involved. As reviewed here, optical imaging is now frequently viewed as an indispensable technique in the field of biological research. Promoting interdisciplinary collaboration among chemistry, biology and medicine, is necessary to further refine functional fluorescent probes for diagnostic and therapeutic applications. 展开更多
关键词 FLUORESCENT PROBE BIOIMAGING PHARMACOLOGICAL research molecular EVENTS
2019年全球会议行业前瞻(下) 预览
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作者 刘慧慧 《中国会展》 2019年第4期66-71,共6页
本文重点关注北美和欧洲在今年的会议发展趋势,分别从会议活动、策划预算和会议选址三个方面进行了分析。北美地区会议活动美国的内部团队和培训会议颇多,占北美总会议数量的30%。内部会议几乎是高层和董事会会议(该地区第二常见的会议... 本文重点关注北美和欧洲在今年的会议发展趋势,分别从会议活动、策划预算和会议选址三个方面进行了分析。北美地区会议活动美国的内部团队和培训会议颇多,占北美总会议数量的30%。内部会议几乎是高层和董事会会议(该地区第二常见的会议)数量的两倍。2018年北美策划人关注保持会议活动的水平,今年将着眼于提质增量。在我们列出的所有会议参数中,北美的调查受访者预测其中的会议数量。 展开更多
关键词 贸易展 参会人数 受访者 房价上涨 策划人 不列颠哥伦比亚
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Eocene foraminiferal biofacies in Kutch Basin (India) in context of palaeoclimate and palaeoecology
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作者 Sonal Khanolkar Pratul Kumar Saraswati 《古地理学报:英文版》 CSCD 2019年第3期209-224,共16页
The Eocene Epoch passed through multiple hyperthermal events and recorded highest temperatures in the Cenozoic. Very few studies from Eocene palaeotropical sites have recorded changes in shallow marine foraminiferal a... The Eocene Epoch passed through multiple hyperthermal events and recorded highest temperatures in the Cenozoic. Very few studies from Eocene palaeotropical sites have recorded changes in shallow marine foraminiferal assemblages. The present study investigates the foraminiferal biofacies of shallow marine successions from a palaeotropical site in western India (Kutch Basin) to understand the palaeoclimate and its impact on the ecology of foraminifera. The sections were biostratigraphically con strained using planktic and larger benthic foraminifera. Four biofacies are recognized by detrended correspondence analysis of the sample-wise distribution of foraminifera. Low diversity and dwarfed foraminifera characterize Bulimina-Chiloguembelino biofacies (SBZ5/6-SBZ10), corresponding to the interval of Paleocene-Eocene Thermal Maxima (PETM) and Eocene Thermal Maxima 2 (ETM 2). Rectilinear benthic foraminifera and biserial and triserial planktic foraminifera, typical of high runoff, upwelling or eutrophic conditions, are dominant taxa in this biofacies. The specialist taxa increased significantly in Asterigerina-Cibicides biofacies, corresponding to SBZ11 (Early Eocene Climatic Optimum, EECO), and the environment became oligotrophic. The Jenkinsina-Brizalina biofacies (E12) is distinguished by foraminiferal assemblage ecologically like that of Bulimina-Chiloguembelina biofacies. It is characterized by high abundance of rectilinear benthic foraminifera and bloom of triserial planktic foraminifera, suggesting eutrophy and high runoff at the initiation of Middle Eocene Climatic Optimum (MECO). The foraminifera were more diverse and abundant in Cibicides-Nonion biofacies. The highly diverse larger benthic foraminiferal assemblage in this biofacies, signify warm and clear-water oligotrophic sea that promoted the development of platform carbonate in Kutch Basin and other basins in western India. The EECO and MECO did not have an adverse impact on shallow marine foraminifera, and particularly the larger benthic foraminifera att 展开更多
关键词 Hyperthermal events Shallow marine Morphogroups Carbonate platform Stable isotopes EOCENE KUTCH BASIN
Hierarchical Research on Pragmatic Failures of Apology in Public Events Under the Vision of New Media 预览
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作者 Kiwi Zhu Rose Mary 《文学与艺术研究:英文版》 2019年第7期702-706,共5页
Under the new media,the dissemination and the influence of public events are often far more profound than traditional media.Therefore,it has gained a high degree of social attention.We take the apology mistakes in pub... Under the new media,the dissemination and the influence of public events are often far more profound than traditional media.Therefore,it has gained a high degree of social attention.We take the apology mistakes in public events as an example,sort out the types and causes of the mistakes into a context,and propose some relevant strategies. 展开更多
关键词 PUBLIC EVENTS apology PRAGMATIC FAILURE
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Modulating neuronal plasticity with choline 预览
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作者 Eunice W. M. Chin Eyleen L.K. Goh 《中国神经再生研究:英文版》 SCIE CAS CSCD 2019年第10期1697-1698,共2页
The American psychologist William James once wrote that nervous tissue seems to be endowed with a “very extraordinary” degree of plasticity. To be plastic means to be capable of being molded, receiving shape, or bei... The American psychologist William James once wrote that nervous tissue seems to be endowed with a “very extraordinary” degree of plasticity. To be plastic means to be capable of being molded, receiving shape, or being made to assume a desired form. This can be achieved consequential to changes in the internal and/or external environment. Being plastic, neurons are highly able to amend their structural and functional output, through alteration of their morphology, activation of intracellular signaling cascades, regulation of synaptic density and neurotransmitter release, or a combination of these events. 展开更多
关键词 The AMERICAN PSYCHOLOGIST TISSUE seems to be endowed COMBINATION of these EVENTS
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安阳市中招体育考试若干问题 预览
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作者 魏建翔 刘波 姜斌 《体育风尚》 2019年第6期260-260,262共2页
对安阳市毕业生做了调查,对其中招体育考试存在的不足做了研究,并提出相应建议,旨在为中招体育考试制度的进一步完善提供理论基础。
关键词 体育 考试 项目
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