期刊文献+
共找到225篇文章
< 1 2 12 >
每页显示 20 50 100
Kinetic, Isotherm and Thermodynamic Studies of the Adsorption of Thymol Blue onto Powdered Activated Carbons from <i>Garcinia cola Nut</i>Shells Impregnated with H<sub>3</sub>PO<sub>4</sub>and KOH: Non-Linear Regression Analysis 认领
1
作者 Idris-Hermann Tiotsop Kuete Donald Raoul Tchuifon Tchuifon +2 位作者 George Nche Ndifor-Angwafor Arnaud Tamo Kamdem Solomon Gabche Anagho 《封装与吸附期刊(英文)》 2020年第1期1-27,共27页
In this work, activated carbons (ACs) prepared by chemical activation of garcinia cola nut shell impregnated with H3PO4 (CBH2/1) and KOH (CBK1/1) were used to study the kinetics, equilibrium and thermodynamics of the ... In this work, activated carbons (ACs) prepared by chemical activation of garcinia cola nut shell impregnated with H3PO4 (CBH2/1) and KOH (CBK1/1) were used to study the kinetics, equilibrium and thermodynamics of the adsorption of thymol blue from aqueous solution. The characterization of ACs showed the BET measurements gave surface area and total pore volume respectively of 328.407 m2·g-1 and 0.1032 cm3·g-1 for CBH2/1 and 25.962 m2·g-1 and 0.03 cm3·g-1for CBK1/1;elemental analysis showed a high percentage of carbon in both ACs. Influence of parameters such as initial pH, contact time, adsorbent mass, initial concentration, ionic strength and the effect of temperature on the removal of thymol blue from aqueous solution were studied in batch mode. The studies showed that equilibrium adsorption was attained after 60 minutes for the two ACs, adsorption capacity increased with increasing concentration of thymol blue, and maximum adsorption capacity was obtained at an acidic environment with pH 2. Avrami’s non-linear kinetic expression was the best suited for describing the adsorption kinetics of thymol blue onto ACs, while equilibrium data showed that the three-parameter isotherms better described the adsorption process since R2 > 0.96, and the error functions were lowest for all of them. Maximum adsorption capacity values obtained using the three-parameter Fritz-Schlunder equation were 32.147 mg·g-1 for CBH2/1 and 67.494 mg·g-1 for CBK1/1. The values of the model parameters g and mFS respectively, obtained using the Redlich-Peterson and Fritz-Schlunder III isotherms below 1, showed that the adsorption of thymol blue by the ACs occurred on heterogeneous surfaces. Thermodynamic analyses of the data of the adsorption of thymol blue onto ACs revealed that the adsorption process was temperature dependent, endothermic and spontaneous. 展开更多
关键词 GARCINIA COLA Nut Shell Chemical Activation Elemental Analysis Non-Linear Regression ADSORPTION Isotherms ADSORPTION KINETIC Models
在线阅读 免费下载
基于衰减全反射红外光谱法的宣纸上国画颜料直接无损鉴别 认领
2
作者 宋丹丹 魏雁红 +1 位作者 郭文娟 谢樟华 《精细石油化工》 CAS 北大核心 2020年第3期56-60,共5页
利用衰减全反射红外光谱法(ATR-FTIR),对于宣纸上的花青与藤黄颜料进行无损测试。结果表明,ATR-FTIR技术可以直接测量出宣纸上的花青与藤黄的特征化学信息,并可利用特征吸收峰对该颜料进行鉴别。而且花青与藤黄的混合方式对检测结果影... 利用衰减全反射红外光谱法(ATR-FTIR),对于宣纸上的花青与藤黄颜料进行无损测试。结果表明,ATR-FTIR技术可以直接测量出宣纸上的花青与藤黄的特征化学信息,并可利用特征吸收峰对该颜料进行鉴别。而且花青与藤黄的混合方式对检测结果影响较小,使用ATR-FTIR技术对以宣纸为基底的画作进行直接无损测量,并确定花青与藤黄是否存在。 展开更多
关键词 衰减全反射红外光谱法 中国画颜料 花青 藤黄 无损鉴别
在线阅读 下载PDF
Morphological Diversity and Distribution of <i>Garcinia kola</i>Heckel (Clusiaceae) in Two Agro-Ecological Areas of Côte d’Ivoire 认领
3
作者 Any Olivier Komenan Kouamé Kévin Koffi +5 位作者 Ahou Anique Gbotto Moussa Kone Doffou Sélastique Akaffou Kouakou Laurent Kouakou Kouadio Ignace Kouassi Bi Irié Arsène Zoro 《美国植物学期刊(英文)》 2019年第10期1871-1887,共17页
The purpose of this study is to determine the morphological diversity and distribution of Garcinia kola Heckel (Clusiaceae) in two preferential agro-ecological growth areas in Cote d’Ivoire, for the sustainable manag... The purpose of this study is to determine the morphological diversity and distribution of Garcinia kola Heckel (Clusiaceae) in two preferential agro-ecological growth areas in Cote d’Ivoire, for the sustainable management of the species. Ninety-four (94) trees of G. kola were sampled in Affery (south) and Biankouma (west) and characterized on the basis of 13 quantitative characteristics of the fruit, the general appearance of a plant, leaves and seeds. This study revealed the existence of very significant variability and differences within the trees sampled for most characteristics. Very strong correlations were found among the characteristics of the fruits. On the basis of these characteristics, it emerged that the fruits of the Biankouma area are larger than those of Affery. Multivariate analyses show that diversity is structured with tree distribution into four distinct groups based on the following discriminating characteristics: fruit height (Hfr), leaf width (largF), seed mass (Mgr) and trunk diameter (Dm). These parameters can be used as a basis for selecting and maintaining the high variability of G. kola. Analysis of the geographical distribution of trees, based on the nearest neighbour model, revealed an aggregate distribution in both areas. 展开更多
关键词 GARCINIA kola Heckel Morphological Variability GEOGRAPHICAL DISTRIBUTION Discriminating Characteristics
在线阅读 免费下载
Hepatotoxicity associated with Garcinia cambogia:A case report 认领
4
作者 Muhammad Nadeem Yousaf Fizah S Chaudhary +1 位作者 Seyed Mohammad Hodanazari Charmian D Sittambalam 《世界肝病学杂志:英文版(电子版)》 2019年第11期735-742,共8页
BACKGROUND Herbal supplements(HS)for weight loss are perceived to be“safe”and“natural”,as advertised in ads,however,hepatotoxicity can be associated with consumption of some HS.Use of HS may be missed,as the patie... BACKGROUND Herbal supplements(HS)for weight loss are perceived to be“safe”and“natural”,as advertised in ads,however,hepatotoxicity can be associated with consumption of some HS.Use of HS may be missed,as the patient may not report these unless specifically asked about these products,since they are often not thought of as medications with potential side effects or interaction potential.CASE SUMMARY We reported a case of a 21-year-old female with morbid obesity who presented with abdominal pain for 1 wk associated with nausea,vomiting,anorexia and myalgias.She denied smoking tobacco,drinking alcohol,usage of illicit drugs,hormonal contraceptives,or energy drinks.There was no significant past medical or family illnesses.Her laboratory workup revealed acute liver failure.The workup for possible etiologies of acute liver failure was unremarkable.She was using a weight loss herbal supplement“Garcinia cambogia”for 4 wks.This case demonstrates the association of acute liver failure with Garcinia cambogia.CONCLUSION Medical reconciliation of HS should be performed in patients with suspected acute liver failure and early discontinuation of HS can prevent further progression of drug induced hepatoxicity. 展开更多
关键词 HEPATOTOXICITY Drug induced LIVER injury Acute LIVER failure HERBAL SUPPLEMENTS GARCINIA cambogia OBESITY Case report
在线阅读 免费下载
The preparation of Garcinia Glycosides solid dispersion and intestinal absorption by rat in situ single pass intestinal perfusion 认领
5
作者 Shengnan Li Jingchao Ji +4 位作者 Yinghui Chen Ye Chen Ju Liu Yang Wang Hongsheng Liu 《制药与生物制药研究杂志(英文)》 2019年第1期15-20,共6页
Garcinia Glycosides is a candidate drug obtained by structural modification of Gambogic Acid (GA), which was acquired through High Throughput Screening(HTS). As Garcinia Glycosides is an effective but insoluble anti-t... Garcinia Glycosides is a candidate drug obtained by structural modification of Gambogic Acid (GA), which was acquired through High Throughput Screening(HTS). As Garcinia Glycosides is an effective but insoluble anti-tumor drug, the aim of this study was to obtain a solid dispersion form Garcinia Glycosides by using solvent-melt method so that improve the solubility and dissolution rate. The solid dispersion was characterized by High Performance Liquid Chromatography (HPLC), infrared spectroscopy and evaluated the intestinal absorption of the drug by rat in situ single pass intestinal perfusion. The results showed the increase of solubility, dissolution velocity and absorption compared to other forms. This indicated that solid dispersion could greatly improve the relative bioavailability of Garcinia Glycosides in vivo. 展开更多
关键词 GARCINIA GLYCOSIDES solid dispersion INTESTINAL PERFUSION in SITU single-pass PERFUSION method
在线阅读 免费下载
New phenylpyridone derivatives from the Penicillium sumatrense GZWMJZ-313,a fungal endophyte of Garcinia multiflora 认领
6
作者 Yanchao Xu Liping Wang +7 位作者 Guoliang Zhu Mingxing Zuo Qianyu Gong Wenwen He Mingpeng Li Chunmao Yuan Xiaojiang Hao Weiming Zhu 《中国化学快报:英文版》 SCIE CAS CSCD 2019年第2期431-434,共4页
Citridones E-G (1-3), three new phenylpyridone derivatives together with two known curvularins (4 and 5) were isolated from the solid culture of the endophytic fungus Penicillium sumatrense GZWMJZ-313 in Garcinia mult... Citridones E-G (1-3), three new phenylpyridone derivatives together with two known curvularins (4 and 5) were isolated from the solid culture of the endophytic fungus Penicillium sumatrense GZWMJZ-313 in Garcinia multiflora. The structures of new compounds were determined in the light of spectroscopic data,X-ray and ECD calculation. Compounds 1 and 3 are racemates, while compound 2 is optically pure.Compounds 1 and 4 showed antibacterial and antifungal activities against Staphylococcus aureus,Pseudomonas aeruginosa, Clostridium perfringens, Escherichia coli and Candida albicans with MIC values ranging from 8 μg/mL to 64 μg/mL. 展开更多
关键词 PENICILLIUM sumatrense GARCINIA multiflora PYRIDONES ANTIBACTERIAL activities ENDOPHYTIC FUNGI
Garcinia xanthochymus extract protects PC12 cells from H2O2-induced apoptosis through modulation of PI3K/AKT and NRF2/HO-1 pathways 认领
7
作者 XU Jing GAN Sheng +4 位作者 LI Jun WAND De-Bing CHEN Yu HU Xin YANG Guang-Zhong 《中国天然药物:英文版》 SCIE CAS CSCD 2017年第11期825-833,共9页
关键词 GARCINIA xanthochymus Oxidative stress PC12 PI3K/AKT pathway Nrf2/HO-1 signaling PATHWAYS
云南藤黄育苗技术及其发展前景 认领 被引量:1
8
作者 付玉嫔 祁荣频 +3 位作者 李思广 司马永康 许林红 尹艾萍 《林业科技通讯》 2017年第2期35-37,共3页
云南藤黄(Garcinia yunnanensis Hu)是一种具有较大开发前景的野生水果和药用植物。通过对云南藤黄的特性和育苗技术研究,详述其生物生态学特性、育苗技术和移植方法,另外还介绍了其发展前景,为云南藤黄的人工培育提供技术指导。
关键词 云南藤黄 GARCINIA yunnanensis HU 育苗 药用资源
藤黄酸的提取分离 认领 被引量:1
9
作者 姜守刚 张星垚 +1 位作者 袁颖洁 祖元刚 《中国卫生标准管理》 2017年第3期106-108,共3页
藤黄酸(Gambogic acid),是由中药藤黄中提取出的物质,现已广泛的应用到临床当中,藤黄酸的临床要用价值为抗癌活性功能,临床实验研究后发现,藤黄酸能够有效对人体外部肝癌细胞进行杀灭作用,且随着藤黄酸使用时间与使用剂量的增加,药物... 藤黄酸(Gambogic acid),是由中药藤黄中提取出的物质,现已广泛的应用到临床当中,藤黄酸的临床要用价值为抗癌活性功能,临床实验研究后发现,藤黄酸能够有效对人体外部肝癌细胞进行杀灭作用,且随着藤黄酸使用时间与使用剂量的增加,药物的抗癌作用也在逐步增加,通过动物实验对藤黄酸进行用药效果研究后发现,藤黄酸对白血病小鼠的治疗效果显著,且能够对体外非致病性病原虫产生抑制作用,在临床上,藤黄酸被广泛应用于乳腺癌、淋巴瘤、皮肤癌、胃癌等疾病当中,且不会对患者的其他身体机能与身体健康造成损害。本文将藤黄酸的提取工艺进行分析,总结藤黄酸提取分离效果。 展开更多
关键词 藤黄 藤黄酸 提取分离
在线阅读 下载PDF
藤黄酸的抗肿瘤机制 认领 被引量:1
10
作者 张文典 徐祖敏 余忠华 《国际肿瘤学杂志》 CAS 2016年第4期293-295,共3页
目前发现藤黄酸可通过不同机制在多种肿瘤细胞中发挥抗肿瘤作用,包括诱导细胞凋亡,抑制端粒末端转移酶和拓扑异构酶活性,抑制热休克蛋白和通道蛋白表达,抑制肿瘤血管生成和转移,逆转肿瘤多药耐药,提示藤黄酸有望成为新型抗肿瘤药... 目前发现藤黄酸可通过不同机制在多种肿瘤细胞中发挥抗肿瘤作用,包括诱导细胞凋亡,抑制端粒末端转移酶和拓扑异构酶活性,抑制热休克蛋白和通道蛋白表达,抑制肿瘤血管生成和转移,逆转肿瘤多药耐药,提示藤黄酸有望成为新型抗肿瘤药物,且仍需进一步探索其在抗肿瘤领域的价值。 展开更多
关键词 藤黄属 抗肿瘤药 肿瘤
天然产物oblongifolin C诱导ROS和线粒体降解 认领 被引量:2
11
作者 程敏 许玮 +3 位作者 刘磊 谢伟东 徐宏喜 许乃寒 《世界中医药》 CAS 2016年第7期1141-1144,共4页
目的:探讨藤黄属植物中提取的多环多异戊烯基间苯三酚类天然小分子化合物oblongifolin C(OC)对细胞线粒体功能和细胞凋亡的影响。方法:以野生型和促凋亡基因bax/bak双敲除的小鼠胚胎成纤维细胞MEF和人结肠癌细胞HCT116为研究模型,... 目的:探讨藤黄属植物中提取的多环多异戊烯基间苯三酚类天然小分子化合物oblongifolin C(OC)对细胞线粒体功能和细胞凋亡的影响。方法:以野生型和促凋亡基因bax/bak双敲除的小鼠胚胎成纤维细胞MEF和人结肠癌细胞HCT116为研究模型,通过流式细胞术,共聚焦显微术和蛋白质免疫印迹法检测OC对ROS,线粒体功能和细胞凋亡的影响。结果:OC能够诱导细胞产生ROS,破坏线粒体结构,降低线粒体膜电位,最终造成线粒体降解和细胞内ATP耗竭,使细胞走向凋亡。结论:OC能通过多条途径诱导细胞凋亡,是一种极有抗癌潜力的天然化合物。 展开更多
关键词 藤黄 Oblongifolin C ROS 线粒体 凋亡
在线阅读 下载PDF
Cytotoxicity study of ethanol extract of the stem bark of asam kandis (Garcinia cowa Roxb.) on T47D breast cancer cell line 认领
12
作者 Elidahanum Husni Faras Nahari +2 位作者 Yan Wirasti Fatma Sri Wahyuni Dachriyanus 《亚太热带生物医学杂志:英文版》 2015年第3期249-252,共4页
Objective:To investigate the cytotoxic effect of ethanol extract of the stem bark of asam kandis[Garcinia cowa Roxb.(G.cowa)]on T47 D breast cancer cell line.Methods:The cytotoxicity of ethanol extract was carried o... Objective:To investigate the cytotoxic effect of ethanol extract of the stem bark of asam kandis[Garcinia cowa Roxb.(G.cowa)]on T47 D breast cancer cell line.Methods:The cytotoxicity of ethanol extract was carried out against human breast cancer cell line(T47D) by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide colorimetric assay.The extract was added at various concentrations(0.1.1,10 and 100 μg/mL).The level of cytotoxicity was determined by calculating the level of IC<sub>50</sub>,that was based on the percentage of the cell death after 24 h treatment with the extract.Cell morphological changes were observed by using inverted microscope.Results:The 3-(4.5-dimelhylthiazol-2-yl)-2.5-diphenyltelrazolium bromide assay showed that ethanol extract of G.cowa exhibited significant cytotoxic effect on T47 D with IC<sub>50</sub> value of(5.10+1.68) μg/mL.Morphological alteration of the cell lines after exposure to ethanol extract of G.cowa was observed under phase contrast microscope in a dosc-dependent manner.ConclusionsThe results suggest the possible use of ethanol extract of asam kandis for preparing herbal medicine for cancer-related ailments. 展开更多
关键词 GARCINIA cowa Roxb CYTOTOXICITY T47D BREAST CANCER cell LINE
Proteomics analysis of antimalarial targets of Garcinia mangostana Linn. 认领
13
作者 Wanna Chaijaroenkul Artitiya Thiengsusuk +2 位作者 Kanchana Rungsihirunrat Stephen Andrew Ward Kesara Na-Bangchang 《亚太热带生物医学杂志:英文版》 2014年第7期515-519,共5页
Objective:To investigate possible protein targets for antimalarial activity of Garcina mangostana Linn.(G.mangostana)(pericarp)in 3D7 Plasmodium falciparum clone using 2-dimensional electrophoresis and liquid chr... Objective:To investigate possible protein targets for antimalarial activity of Garcina mangostana Linn.(G.mangostana)(pericarp)in 3D7 Plasmodium falciparum clone using 2-dimensional electrophoresis and liquid chromatography mass-spectrometry(LC/MS/MS).Methods:3D7 Plasmodium falciparum was exposed to the crude ethanolic extract of G.mangostana Linn.(pericarp)at the concentrations of 12μg/mL(1C<sub>50</sub>level:concentration that inhibits parasite growth by 50%)and 30μg/mL(1C<sub>90</sub>level:concentration that inhibits parasite growth by 90%)for 12 h.Parasite proteins were separated by 2-dimensional electrophoresis and identified by LC/MS/MS.Results:At the IC<sub>50</sub>concentration,about 82%of the expressed parasite proteins were matched with the control(non-exposed),while at the IC<sub>90</sub>concentration,only 15%matched proteins were found.The selected protein spots from parasite exposed to the plant extract at the concentration of 12μg/mL were identified as eneymes that play role in glycolysis pathway,i.e.,phosphoglyeerate mutase putative,L-lactate dehydrogenase/glyceraldehyde-3-phosphate dehydrogenase,and fruetose-bisphosphate aldolase/phosphoglyeerate kinase.The proteosome was found in parasite exposed to 30μg/mL of the extract.Conclusions:Results suggest that proteins involved in the glycolysis pathway may be the targets for antimalarial activity of G.mangostana Linn.(pericarp). 展开更多
关键词 MALARIA PROTEOMICS GARCINIA mangostana Linn.
Antimalarial activity and toxicity of Garcinia mangostana Linn. 认领 被引量:1
14
作者 Ratchanu Bunyong Wanna Chaijaroenkul +1 位作者 Tullayakorn Plengsuriyakarn Kesara Na-Bangchang 《亚太热带医药杂志:英文版》 SCIE 2014年第9期693-698,共6页
Objective:To investigate the antimalarial activity and toxicity of the crude ethanolic extract of its pericarp both in vitro and in vim.Methods:The antimalarial activity of Gareinja mangostana(G.mangostana)Linn.ext... Objective:To investigate the antimalarial activity and toxicity of the crude ethanolic extract of its pericarp both in vitro and in vim.Methods:The antimalarial activity of Gareinja mangostana(G.mangostana)Linn.extract against 3D7 and Kl Plasmodium falciparum(P.falciparum)clone were assessed using SYBR green I-based assay.A 4-day suppressive test of Plasmodium berghei{P.berghei)infected mouse was performed to investigate in vivo antimalarial activity.Results:The in vitro antimalarial activity was seleclive(SI】5?and classified as weak and good lo moderate activity against both 3D7 and K1 P.falciparum,clones with median IC<sub>50</sub>(range)values of 11.12(10.94-11.29)and 7.54(6.80-7.68)μg/mL,respectively.The extract was considered nontoxic to mice.The maximum tolerated doses for acute and subacute toxicity in mice were 5 000and 2 000 mg/kg,respectively.Median(range)parasite density on day 4 of the negative control group(25%Tween-80),mice treated with 250,500,1000,and 2 000 mg/kg body weight of the extract,and 10 mg/kg body weight of chloroquine for 14 d were 12.8(12.2-13.7),11.4(9.49-13.8),11.6(9.9-12.5),11.7(10.6-12.8),10.9(9.4-11.6)and 0(0-0)%respectively.Parasite density on day 4in the control group treated with Tween-80 was higher than the groups treated with chloroquine and all dose levels of the extract.Conclusions:G.mangostana linn,showed weak antimalarial activity of the extract both in vitro and in vivo could be due to limitation of absorption of the active compounds. 展开更多
关键词 GARCINIA mangostana LINN PLASMODIUM FALCIPARUM PLASMODIUM BERGHEI ANTIMALARIAL activity
中国产藤黄属植物中抗肿瘤活性化学成分的研究概况 认领 被引量:9
15
作者 付文卫 谭红胜 徐宏喜 《药学学报》 CAS CSCD 北大核心 2014年第2期166-174,共9页
藤黄属(Garcinia L.)植物具有广泛的药用价值,是天然[口山]酮类、苯甲酮类等化合物的主要资源之一,这类成分具有新颖多变的结构和显著的生物活性,特别在抗肿瘤方面的研究,成为近年来天然产物的研究热点之一。本文结合作者多年来... 藤黄属(Garcinia L.)植物具有广泛的药用价值,是天然[口山]酮类、苯甲酮类等化合物的主要资源之一,这类成分具有新颖多变的结构和显著的生物活性,特别在抗肿瘤方面的研究,成为近年来天然产物的研究热点之一。本文结合作者多年来在该领域的研究工作,对中国产藤黄属植物中具有显著抗肿瘤生物活性的化学成分和生物活性的研究进展进行介绍。 展开更多
关键词 藤黄属 化学成分 抗肿瘤活性 [口山]酮 苯甲酮
岭南山竹子叶化学成分研究 认领 被引量:5
16
作者 王宁 汤丽昌 +2 位作者 姚海萍 杨先会 邓世明 《广西植物》 CAS CSCD 北大核心 2013年第5期共5页
采用色谱技术分离岭南山竹子叶的化学成分,根据理化性质和波谱数据鉴定化合物的结构。从岭南山竹子叶提取物中分离了11个化合物,鉴定为异植物醇(Ⅰ),α-Tocospiro B(Ⅱ),正十一烷(Ⅲ),棕榈酸(Ⅳ),(+)-(3R)-3-hydroxy-4,4-dimethyl-4-but... 采用色谱技术分离岭南山竹子叶的化学成分,根据理化性质和波谱数据鉴定化合物的结构。从岭南山竹子叶提取物中分离了11个化合物,鉴定为异植物醇(Ⅰ),α-Tocospiro B(Ⅱ),正十一烷(Ⅲ),棕榈酸(Ⅳ),(+)-(3R)-3-hydroxy-4,4-dimethyl-4-butyrolactone(Ⅴ),苯甲酸(Ⅵ),3,4-Dihydroxy-acetophenone(Ⅶ),反式对羟基桂皮酸(Ⅷ),3-甲氧基-4-羟基-苯甲酸(Ⅸ),β-谷甾醇(Ⅹ),胡萝卜苷(Ⅺ)。以上化合物均为首次从该种植物中分离得到。 展开更多
关键词 藤黄属 岭南山竹子叶 化学成分
在线阅读 免费下载
岭南山竹子树皮化学成分研究 认领 被引量:5
17
作者 余辅松 邓世明 +3 位作者 李慧 姚海萍 杨先会 刘春宇 《中南药学》 CAS 2013年第4期241-244,共4页
目的研究藤黄属植物岭南山竹子树皮中的化学成分。方法利用硅胶、Sephadex LH-20等色谱法对山竹子树皮中的化学成分进行分离以及根据所获单体化合物的理化性质和光谱数据(紫外、核磁共振、质谱)鉴定其结构。结果从山竹子树皮中分离得... 目的研究藤黄属植物岭南山竹子树皮中的化学成分。方法利用硅胶、Sephadex LH-20等色谱法对山竹子树皮中的化学成分进行分离以及根据所获单体化合物的理化性质和光谱数据(紫外、核磁共振、质谱)鉴定其结构。结果从山竹子树皮中分离得到7个单体化合物,经鉴定分别为10-hydroxybotryococcene(1)、peplusol(2)、stigmast-4-en-3-one(3)、parvifiol(4)、1,2-benzenedicarboxylic acid bis(2-methyl heptyl)ester(5)、camboginol(6)、pedunxanthone C(7)。结论化合物1~7均为首次从该种植物中分离得到。 展开更多
关键词 藤黄属 岭南山竹子 化学成分
在线阅读 免费下载
Hydroxycitric acid does not promote inflammation or liver toxicity 认领 被引量:1
18
作者 Dallas L Clouatre Harry G Preuss 《世界胃肠病学杂志:英文版(电子版)》 SCIE CAS 2013年第44期8160-8162,共3页
Garcinia cambogia extract(GC)with its active component consisting of hydroxycitric acid(HCA)is widely utilized for weight loss.Various HCA salts are available,including calcium,magnesium,potassium and mixtures of the... Garcinia cambogia extract(GC)with its active component consisting of hydroxycitric acid(HCA)is widely utilized for weight loss.Various HCA salts are available,including calcium,magnesium,potassium and mixtures of these.Experimentally,these salts exhibit different properties with some,but not all,improving glucose tolerance and blood pressure.Recently,obesity-prone C57BL/6J mice were fed a high-fat diet(HFD,45 kcal%fat)with or without GC(1%,w/w)for 16 wk.The active arm reduced visceral fat,adipocyte size and serum glucose,yet purportedly also exhibited hepatic collagen accumulation,lipid peroxidation and increased mRNA levels of genes related to oxidative stress.The latter findings are at odds with a large body of animal and human studies that have been conducted on the safety and efficacy of HCA.This literature shows HCA to be protective against the liver toxicity associated with ethanol and dexamethasone administration,and to maintain serum aspartate aminotransferase,alanine aminotransferase and alkaline phosphatase at near normal levels.In both animal and clinical literature,elevated intakes of HCA per se have not led to signs of inflammation or hepatotoxicity.The compound has been found to reduce markers of inflammation in brain,intestines,kidney and serum. 展开更多
关键词 GARCINIA cambogia HEPATIC COLLAGEN HEPATIC INFLAMMATION HEPATIC oxidative stress Hydroxycitric acid Metabolic syndrome Tumor NECROSIS FACTOR-A Weight loss
在线阅读 免费下载
Garcinia Cambogia attenuates diet-induced adiposity but exacerbates hepatic collagen accumulation and inflammation 认领 被引量:1
19
作者 Young-Je Kim Myung-Sook Choi +3 位作者 Yong Bok Park Sang Ryong Kim Mi-Kyung Lee Un Ju Jung 《世界胃肠病学杂志:英文版(电子版)》 SCIE CAS 2013年第29期4689-4701,共13页
AIM: To investigate long-term effects of Garcinia Cambogia (GC), weight-loss supplement, on adiposity and non-alcoholic fatty liver disease in obese mice. METHODS: Obesity-prone C57BL/6J mice were fed a high-fat diet... AIM: To investigate long-term effects of Garcinia Cambogia (GC), weight-loss supplement, on adiposity and non-alcoholic fatty liver disease in obese mice. METHODS: Obesity-prone C57BL/6J mice were fed a high-fat diet (HFD, 45 kcal% fat) with or without GC (1%, w/w) for 16 wk. The HFD contained 45 kcal% fat, 20 kcal% protein and 35 kcal% carbohydrate. They were given free access to food and distilled water, and food consumption and body weight were measured daily and weekly, respectively. Data were expressed as the mean ± SE. Statistical analyses were performed using the statistical package for the social science software program. Student’s t test was used to assess the differences between the groups. Statistical significance was considered at P 【 0.05. RESULTS: There were no significant changes in body weight and food intake between the groups. However, the supplementation of GC significantly lowered visceral fat accumulation and adipocyte size via inhibition of fatty acid synthase activity and its mRNA expression in visceral adipose tissue, along with enhanced enzymatic activity and gene expression involved in adipose fatty acid β-oxidation. Moreover, GC supplementation resulted in significant reductions in glucose intolerance and the plasma resistin level in the HFD-fed mice. However, we first demonstrated that it increased hepatic collagen accumulation, lipid peroxidation and mRNA levels of genes related to oxidative stress (superoxide dismutase and glutathione peroxidase) and inflammatory responses (tumor necrosis factor-α and monocyte chemoattractant protein-1) as well as plasma alanine transaminase and aspartate transaminase levels, although HFD-induced hepatic steatosis was not altered. CONCLUSION: GC protects against HFD-induced obesity by modulating adipose fatty acid synthesis and β-oxidation but induces hepatic fibrosis, inflammation and oxidative stress. 展开更多
关键词 GARCINIA Cambogia Anti-adiposity Metabolic changes HEPATIC collagen accumulation HEPATIC INFLAMMATION HEPATIC oxidative stress
在线阅读 免费下载
Effect of Added Garcinia Fruit on Total Phenolic Compound Content, Antioxidant Properties and Quality Changes of the Southern Sour Curry Paste, Keang-hleung, during Storage 认领
20
作者 Preeyaporn Promjiam Sunisa Siripongvutikorn Worapong Usawakesmanee 《食品与营养科学(英文)》 2013年第8期812-820,共9页
The favorite soup for Thai particularly in the southern part is Southern sour curry or Keang-hleung soup. The ingredients used in the paste are turmeric rhizome, garlic, shallot and chili. However, for making the sour... The favorite soup for Thai particularly in the southern part is Southern sour curry or Keang-hleung soup. The ingredients used in the paste are turmeric rhizome, garlic, shallot and chili. However, for making the sour soup, the souring agent such as lime juice, tamarind pod or garcinia, fruit is added. This study aimed to compare quality changes, total phenolic compound and antioxidant properties of the pastes as affected of added garicia fruit during storage. It was found that the total phenolic compound content of basic paste without the garcinia, garcinia Keang-hleung paste and garcinia Keang-hleung paste without salt decreased as increased storage time. Moreover, the DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity and the ferric reducing power (FRAP) activity of the basic paste without the garcinia decreased as increased storage time. However, the DPPH radical scavenging activity and the FRAP activity of the garcinia Keang-hleung paste with and without salt increased during 2 months of storage period and then decreased as increased storage time. Total viable count (TVC) of all paste samples were in the range of 102 - 103 cfu/g. Yeast and mold counts of basic and garcinia Keang-hlueng paste were less than 30 cfu/g during storage. While, yeast and mold counts of garcinia Keang-hlueng paste without salt were less than 102 cfu/g during storage. Lactic acid bacteria counts of garcinia Keang-hlueng paste were less than 30 cfu/g during storage. While, lactic acid bacteria counts of the basic and garcinia Keang-hlueng paste without salt were less than 102 cfu/g during storage. However, Staphylococcus aureus, Bacilluus cereus, Clostridium perfringens, Salmonella spp., Escherichia coli and coliforms were not detected in all treatments throughout the storage period. 展开更多
关键词 Keang-hleung PASTE Southern SOUR CURRY GARCINIA Antioxidant Shelf-Life Thailand
在线阅读 免费下载
上一页 1 2 12 下一页 到第
使用帮助 返回顶部 意见反馈